Biodegradable additives modulate ganciclovir release rate from PLGA microspheres destined to intraocular administration

Letters in Drug Design and Discovery

Volumn 2, Issue 2, 2005, Pages 148-149

  Barcia, Emilia ^a   Herradón, Cristina ^a   Herrero Vanrell, Rocío ^a,b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b Faculty of Pharmacy   (Spain)

Author keywords

Alpha tocopherol; Cytomegalovirus retinitis; Ganciclovir; Glyceryl tricaprylate caprate; Intravitreal administration; Microspheres

Indexed keywords

ALPHA TOCOPHEROL; DRUG ADDITIVE; GANCICLOVIR; MICROSPHERE; MIGLYOL; POLYGLACTIN;

ARTICLE; BIODEGRADABILITY; DRUG FORMULATION; DRUG RELEASE; ENDOPHTHALMITIS; HUMAN CYTOMEGALOVIRUS; INTRAOCULAR DRUG ADMINISTRATION; PRIORITY JOURNAL; RETINA DETACHMENT; RETINITIS; SLOW DRUG RELEASE; VITREOUS HEMORRHAGE;

EID: 15244354391     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/1570180053175188     Document Type: Article

References (9)

1. Jabs, D.A. Retina. 1998, 18, 395-398.
2. Jacobson, M.A.; Mills, J. Ann. Intern. Med., 1998, 108, 585-594.
3. Whitley, R.J.; Jacobson, M.A.; Friedberg, D.M.; Holland, G.N.; Jabs, D.A.; Dieterich, D.T.; Hardy, W.D.; Polis, M.A.; Deutsch, T.A.; Feinberg, J.; Spector, S.A.; Walmsley, S.; Drew, W.L.; Powderly, W.O.; Griffiths, P.D.; Benson, C.A.; Kessler, H.A. Arch. Intern. Med., 1998, 158(9), 957-69.
4. Musch, D.C.; Martin, D.F.; Gordon, J.F. New Engl. J. Med., 1997, 337, 83-90.
5. Kunimatsu, S.; Fujino, Y.; Nagata, Y.; Ono, K.; Mochizuki, M.; Numaga, J.; Kawashima, H.: Araie, M. Br. J. Ophthalmol., 2002, 86(8), 869-71.
6. Barnard, D. Keneddy Inst. Ethics. J., 2002, 12(2), 159-74.
7. Herrero-Vanrell, R. and Refojo, M.F. Adv. Drug Deliv. Rev., 2001, 52, 5-16.
8. Veloso, A.A.S.; Zhu, Q.; Herrero-Vanrell, R.; Refojo, M.F. Invest. Ophthalmol. Vis. Sci., 1997, 38, 665-675.
9. Haas, A.L.; Boscoboinik, D.; Mojon, D.S.; Bohnke, M.; Azzi, A. Ophthalmic. Res., 1996, 25(3), 171-175.