Nicotinamide trials in diabetes intervention: Does a metabolite provide benefit? [3]

Medical Hypotheses

Volumn 64, Issue 5, 2005, Pages 1062-1063

  Gosteli, Jacques ^a  

^a Cerecon AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE DERIVATIVE; PYRIDINIUM DERIVATIVE;

ALLOXAN DIABETES MELLITUS; CELL PROLIFERATION; COMPLEX FORMATION; DIABETES MELLITUS; DNA SYNTHESIS; DRUG ACTIVITY; HUMAN; HYDROLYSIS; LETTER; NONHUMAN; OXIDATION KINETICS; PRIORITY JOURNAL; REDUCTION KINETICS; SKIN DISEASE;

EID: 15244348628     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.11.019     Document Type: Letter

References (10)

1. Gale EAM + ENDIT Group Members, European Nicotinamide Diabetes Intervention Trial. Lancet 2004;363:925-931
2. L.J. Fischer, J. Falany, and R. Fisher Characteristics of nicotinamide and N′-methylnicotinamide. Protection from alloxan diabetes in mice Toxicol Appl Pharmacol 70 1983 148 155
3. J. Hoshino, U. Kuehne, and H. Kroeger Methylation of nicotinamide in rat liver cytosol and its correlation with hepatocellular proliferation Biochim Biophys Acta 719 3 1982 518 526
4. J. Hoshino, U. Kuehne, and H. Kroeger Enhancement of DNA synthesis and cell proliferation by 1-methylnicotinamide in rat liver cells In culture Biochem Biophys Res Commun 105 4 1982 1446 1452
5. J. Gebicki, A. Sysa-Jedrzejowska, J. Adamus, A. Wozniacka, M. Rybak, and J. Zielonka 1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin Pol J Pharmacol 55 2003 109 112
6. A. Lazarow, J. Liambies, and A.J. Tausch Protection against diabetes with nicotinamide J Lab Clin Med 36 1950 249 258
7. M.S. El Ridi, M.M. Abdel Kader, and A. Habib The role of the liver and kidney in the metabolism of nicotinamide in pellagrins and nonpellagrins Acta Physiol Acad Sci Hung 17 1960 429 441
8. G. Pasquariello Tryptophan-nicotinic acid pathway in diabetes mellitus Acta Vitaminol 18 5 1964 225 234
9. T. Matsuura, I. Miyata, and H. Kurata Nicotinamide coenzyme levels in the livers of alloxan-diabetic rats Bitamin 37 1968 423 427
10. M.C. Thomas, C.B. Tikellis, and W.C. Burns Reduced tubular cation transport in diabetes: prevented by ACE inhibition Kidney Internat 63 6 2003 2152 2161