Hyperbranched polymer-drug conjugates with high drug payload for enhanced cellular delivery

Pharmaceutical Research

Volumn 21, Issue 12, 2004, Pages 2185-2195

  Kolhe, Parag ^a   Khandare, Jayant ^a   Pillai, Omathanu ^b   Kannan, Sujatha ^b   Lieh Lai, Mary ^b   Kannan, Rangaramanujam ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

Author keywords

Cell entry; Dendrimers; Hyperbranched polymers; Ibuprofen; Polyglycerol; Polyol

Indexed keywords

CISPLATIN; DICYCLOHEXYLCARBODIIMIDE; ESTER; FLUORESCEIN ISOTHIOCYANATE; GLYCEROL DERIVATIVE; IBUPROFEN; METHANOL; POLYGLYCEROL; POLYMER; POLYOL; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER THERAPY; CARBON NUCLEAR MAGNETIC RESONANCE; CELLULAR DISTRIBUTION; CHEMICAL BOND; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOSOL; DIAGNOSTIC IMAGING; DIALYSIS MEMBRANE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG RELEASE; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SIDE EFFECT; ULTRAVIOLET SPECTROPHOTOMETRY;

CELL LINE, TUMOR; CELL MEMBRANE; DRUG DELIVERY SYSTEMS; FLUORESCEIN-5-ISOTHIOCYANATE; GLYCEROL; HUMANS; PHARMACEUTICAL PREPARATIONS; POLYMERS;

EID: 15244346848     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-004-7670-x     Document Type: Article

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