Analysis of the specificity and thermodynamics of the interaction between low affinity antibodies and carbohydrate antigens using fluorescence spectroscopy

Journal of Immunological Methods

Volumn 297, Issue 1-2, 2005, Pages 203-211

  Engström, Henrik A ^a   Andersson, Per Ola ^a   Ohlson, Sten ^a  

^a LINNAEUS UNIVERSITY   (Sweden)

Author keywords

Carbohydrate; Fluorescence; Monoclonal antibody; Specificity; Transient binding; Weak affinity

Indexed keywords

CARBOHYDRATE ANTIGEN; CELLOBIOSE; GLYCOSIDE; MALTOSE; MONOCLONAL ANTIBODY; PANOSE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; ARTICLE; BINDING AFFINITY; DISSOCIATION CONSTANT; ENTHALPY; ENTROPY; FLUORESCENCE SPECTROSCOPY; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; THERMODYNAMICS;

EID: 15244346043     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.12.010     Document Type: Article

References (20)

1. J.A. Berzofsky, and A.N. Schechter The concepts of crossreactivity and specificity in immunology Mol. Immunol. 18 1981 751
2. L.D. Causey, and D.S. Dwyer Detection of low affinity interactions between peptides and heat shock proteins by chemiluminescence of enhanced avidity reactions (CLEAR) Nat. Biotechnol. 14 1996 348
3. x determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells J. Biol. Chem. 264 1989 9476
4. C.P.J. Glaudemans, C.E. Miller, and E.M. Nashed The measurement of affinity between ligand and antibody using ligand-induced antibody fluorescence change Carbohydr. Res. 300 1997 169
5. M.E. Jolley, and C.P.J. Glaudemans The determination of binding constants for binding between carbohydrate ligands and certain proteins Carbohydr. Res. 33 1974 377
6. C. Jungar, M. Strandh, S. Ohlson, and C.F. Mandenius Analysis of carbohydrates using liquid chromatography-surface plasmon resonance immunosensing systems Anal. Biochem. 281 2000 151
7. K. Karjalainen High sensitivity, low affinity-paradox of T-cell receptor recognition Curr. Opin. Immunol. 6 1994 9
8. K.A. Kronis, and J.P. Carver Specificity of isolectins of wheat germ agglutinin for sialyloligosaccharides: a 360-MHz proton nuclear magnetic resonance binding study Biochemistry 21 1982 3050
9. L. Leickt, A. Grubb, and S. Ohlson Development of monoclonal antibodies against creatine kinase MB2 Scand. J. Clin. Lab. Invest. 62 2002 423
10. H. Ljungberg, S. Ohlson, and S. Nilsson Exploitation of a monoclonal antibody for weak affinity-based separation in capillary gel electrophoresis Electrophoresis 19 1998 461
11. A. Lundblad, K. Schroer, and D. Zopf Radioimmunoassay of a glucose-containing tetrasaccharide using a monoclonal antibody J. Immunol. Methods 68 1984 217
12. C.R. MacKenzie, T. Hirama, S.-J. Deng, D.R. Bundle, S.A. Narang, and N.M. Young Analysis by surface plasmon resonance of the influence of valence on the ligand binding affinity and kinetics of an anti-carbohydrate antibody J. Biol. Chem. 271 1996 1527
13. M. Mammen, S.-K. Choi, and G.M. Whitesides Polyvalent interactions in biological systems: implications for design and use of multivalent ligands and inhibitors Angew. Chem., Int. Ed. 37 1998 2754 (in English)
14. M.W. Nicholson, A.N. Barclay, M.S. Singer, S.D. Rosen, and P.A. van der Merwe Affinity and kinetic analysis of L-selectin (CD62L) binding to glycosylation-dependent cell-adhesion molecule-1 J. Biol. Chem. 273 1998 763
15. S. Ohlson, M. Bergstrom, P. Pahlsson, and A. Lundblad Use of monoclonal antibodies for weak affinity chromatography J. Chromatogr., A 758 1997 199
16. S. Ohlson, C. Jungar, M. Strandh, and C.F. Mandenius Continuous weak-affinity immunosensing Trends Biotechnol. 18 2000 49
17. B. Sigurskjold, E. Altman, and D. Bundle Sensitive titration microcalorimetric study of the binding of Salmonella O-antigenic oligosaccharides by a monoclonal antibody Eur. J. Biochem. 197 1991 239
18. M. Strandh, B. Persson, H. Roos, and S. Ohlson Studies of interactions with weak affinities and low-molecular-weight compounds using surface plasmon resonance technology J. Mol. Recognit. 11 1998 188
19. M. Strandh, H.S. Andersson, and S. Ohlson Weak affinity chromatography Methods Mol. Biol. 147 2000 7
20. D. Zopf, and S. Ohlson Weak-affinity chromatography Nature 346 1990 87