Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring

Journal of Medicinal Chemistry

Volumn 41, Issue 19, 1998, Pages 3727-3735

  Tucker, John A ^a   Allwine, Debra A ^a   Grega, Kevin C ^a   Barbachyn, Michael R ^a,b   Klock, Jennifer L ^a   Adamski, Jenifer L ^a   Brickner, Steven J ^a,c   Hutchinson, Douglas K ^a   Ford, Charles W ^a   Zurenko, Gary E ^a   Conradi, Robert A ^a   Burton, Phillip S ^a   Jensen, Randy M ^a  

^a Animal Health Discovery Research   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; EPEREZOLID; LINEZOLID; N [[3 (4 ACETYLPHENYL) 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 (2 PYRIMIDINYL)] 1 PIPERAZINYL]PHENYL 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 (3 PYRIDAZINYL)] 1 PIPERAZINYL]PHENYL 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [3 (6 METHYLPYRIDAZINYL)]] 1 PIPERAZINYL]PHENYL 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [4 [4 (5 CYANO 2 PYRIDINYL) 1 PIPERAZINYL] 3 FLUOROPHENYL] 2 OXO 1,3 OXAZOLIDIN 5 YL)METHYL]ACETAMIDE; OXAZOLIDINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; CLINICAL TRIAL; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHASE 3 CLINICAL TRIAL; STAPHYLOCOCCUS INFECTION; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; ANTI-BACTERIAL AGENTS; CACO-2 CELLS; ENTEROCOCCUS FAECALIS; HUMANS; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; OXAZOLES; OXAZOLIDINONES; PERMEABILITY; PIPERAZINES; PYRIDINES; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZENES;

EID: 15144354135     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980274l     Document Type: Article

References (34)

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