5-fluorouracil and cisplatin as palliative treatment of advanced oesophageal squamous cell carcinoma: A multicentre randomised controlled trial

European Journal of Surgery

Volumn 164, Issue 11, 1998, Pages 849-857

  Levard, Hugues ^a   Pouliquen, Xavier ^b,i   Hay, Jean Marie ^c,i   Fingerhut, Abe ^d,i   Langlois Zantain, Odile ^e   Huguier, Michel ^f,i   Lozach, Patrick ^g,i   Testart, Jacques ^h,i   Yacher, Bernard ⁱ   Urbajtel, Michel ⁱ   Ley, Françoise ⁱ   Brassier, Didier ⁱ   Elhadad, André ⁱ   Sage, Michel ⁱ   Gayral, Franç ⁱ   Millat, Bertrand ⁱ   Chipponi, Jacques ⁱ   Flamant, Yves ⁱ   Zeitoun, Guy ⁱ   Grandjean, Michel ⁱ   Fagniez, Pierre Louis ⁱ   Rotman, Nelly ⁱ   Cabanis, Patrick ⁱ   Rouffet, François ⁱ   Bugnon, Pierre Yves ⁱ   Gautier Benoît, Claude ⁱ   Desrousseaux, Bernard ⁱ   Lenriot, Jean Pierre ⁱ   Paquet, Jean Chrisophe ⁱ   Rodary, Michel ⁱ   Lacaine, François ⁱ   Oberlin, Philippe ⁱ   Rea, Silvio ⁱ   Bokobza, Bernard ⁱ   Michot, Francis ⁱ   Téniére, Paul ⁱ   Pujol, Jean Paul ⁱ   Marre, Philippe ⁱ   Montariol, Thierry ⁱ   more..

^a Hop Intl de l'Univ de Paris   (France)

^b CENTRE HOSPITALIER VICTOR DUPOUY   (France)

^c HÔPITAL LOUIS MOURIER   (France)

^d CENTRE HOSPITALIER INTERCOMMUNAL   (France)

^e CENTRE HOSPITALIER   (France)

^f HÔPITAL TENON   (France)

^g CHU MORVAN   (France)

^h HÔPITAL CHARLES NICOLLE   (France)

ⁱ NONE

Author keywords

5FU; Antimetabolites; Chemotherapy; Cisplatin; Controlled trial; Oesophageal neoplasm; Oesophageal resection; Palliative resection; Squamous cell carcinoma; Swallowing function

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; EAR NOSE THROAT DISEASE; ESOPHAGUS CANCER; FEMALE; FRANCE; HUMAN; LIVER METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PALLIATIVE THERAPY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TREATMENT PLANNING;

EID: 15144352322     PISSN: 11024151     EISSN: None     Source Type: Journal    
DOI: 10.1080/110241598750005273     Document Type: Article

References (40)

1. Ajani J, Mc Murtrey M, Rich T et al. Combined modality therapy with effective prolonged systemic component for the locally advanced squamous cell carcinoma of the oesophagus. (Abstract). Proc Am Soc Clin Oncol 1987; 6: 82.
2. Akiyama H, Tsurumaru M, Kawamura T, Ono Y. Principles of surgical treatment for carcinoma of the oesophagus. Ann Surg 1981; 194: 438-446.
3. Alberts AS, Burger W, Greef F et al. Severe complications of 5 fluorouracil and cisplatin with concomitant radiotherapy in inoperable non-metastatic squamous cell esophageal cancer after intubation. Early termination of a prospective randomized trial. Eur J Cancer 1992; 45: 1005-1006.
4. Andersen AP, Bersal P, Edsmyr F et al. Irradiation, chemotherapy and surgery in esophageal cancer: a randomized clinical study. Radiother Oncol 1984; 2: 179-188.
5. Cancer Research Campaign Working Party. Trials and tribulations: thoughts on the organisation of multicentric clinical studies. BMJ 1990; 281: 918-920.
6. Carey HW, Hilgenberg AD, Wilkins EW et al. Evaluation of the long term follow-up of neo adjuvant chemotherapy with 5-fluorouracil and cisplatin with surgical resection and possible postoperative radiotherapy and/or chemotherapy in squamous cell carcinoma of the oesophagus. Cancer Invest 1993; 11: 99-105.
7. Coia R, Soffen EM, Schultheiss TE, Martin EE, Hanks GE. Swallowing function in patients with esophageal cancer treated with concurrent radiation and chemotherapy. Cancer 1993; 71: 281-286.
8. De Besi P, Sileni WC, Salvagho L et al. Phase II study of cisplatin, 5FU and allopurinol in advanced esophageal cancer. Cancer Treat Rep 1986; 70: 909-910.
9. Earlam R, Cunha-Melo JR. Oesophageal squamous cell carcinoma: I. A critical review of surgery. Br J Surg 1980; 67: 381-390.
10. Earlam R. Epidemiology of oesophageal cancer from the European point of view. In: Siewert R, Hoelscger AH, eds. Diseases of the oesophagus. Berlin, Springer Verlag 1988: 11-17.
11. Elias D, Spielmann M, Kac J et al. Cancers épidermoï'des de l'œsophage: l'association chimiothérapie puis chirurgie est-elle bénéfique? (Squamous-cell carcinoma of the oesophagus: is combined chemotherapy and surgery of help?). Bull Cancer 1989; 76: 717-727.
12. Fink U, Ries G, Siewert JR. Perioperative Chemotherapie bei Plattenepithel-carzinomen des Ooesophagus. (Perioperative chemotherapy in sqamous-cell carcinoma of the oesophagus). Langenbecks Arch Chir 1987; 372: 145-148.
13. Forastiere AA, Gennis M, Orringer MB, Agha FP. Cisplatin, vinblastine and mitoguazone chemotherapy for epidermoid and adenocarcinoma of the oesophagus. J Clin Oncol 1987; 5: 1143-1149.
14. Gisselbrecht C, Calvo F, Mignot L et al. Fluorouracil (F), Adriamycin (A) and Cisplatin (P) (FAP): combination chemotherapy of advanced esophageal carcinoma. Cancer 1983; 52: 975-977.
15. Herskovic A, Martz K, Al Sharraf M et al. Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med 1992; 326: 1593-1598.
16. Iizuka T, Kakegawa T, Ide H et al. Phase II evaluation of cisplatin and 5 fluorouracil in advanced squamous cell carcinoma of the oesophagus: a Japanese Esophageal Oncology Group Trial. Jpn J Clin Oncol 1992; 22: 172-176.
17. Kasai M, Mori S, Watanabe T. Follow-up results after resection of thoracic esophageal carcinoma. World J Surg 1978; 2: 543-551.
18. Kelsen D. Treatment of advanced esophageal cancer. Cancer 1982; 50: 2576-2581.
19. Kelsen D, Hilaris B, Coonley C et al. Cisplatin. Vindesine and Bleomycin chemotherapy of localregional and advanced esophageal carcinoma. Am J Med 1983; 75: 645-652.
20. Kelsen DP, Minsky B, Smith M et al. Preoperative therapy for esophageal cancer: a randomized comparison of chemotherapy versus radiation therapy. J Clin Oncol 1990; 8: 1352-1361.
21. Kish JA, Weaver A, Jacobs J, Cummings G. Al-Sharraf M. Cisplatin and 5 fluorouracil infusion in patients with recurrent and disseminated epidermoid cancer of the head and neck. Cancer 1984; 53: 1819-1824.
22. Loisou LA, Grigg D, Atkinson M, Robertson C, Bown SG. A prospective comparison of laser therapy and intubation in endoscopic palliation for malignant dysphagia. Gastroenterology 1991; 100: 1303-1310.
23. Lund O, Kimose HH, Aagaard MT, Hasenkam JM, Erlandsen M. Risk stratification and long-term results after surgical treatment of carcinomas of the thoracic oesophagus and cardia. A 25-year retrospective study. J Thorac Cardiovasc Surg 1990; 99: 200-209.
24. Mercke C, Albertsson M, Hambraeus G et al. Cisplatin and 5FU combined with radiotherapy in surgery in the treatment of squamous cell carcinoma of the oesophagus. Palliative effects and tumour response. Acta Oncol 1991; 30: 617-622.
25. Muir CS, Epidémiologie du cancer de l'œsophage en France et dans le monde (Epidemiology of oesophageal carcinoma in France). Gastroenterol Clin Biol 1981; 5: 239-242.
26. Müller JM, Erasmi H, Stelzner M, Zieren U, Pichlmaier H. Surgical therapy of oesophageal carcinoma. Br J Surg 1990; 77: 845-857.
27. Murray GD, Statistical aspects of research methodology. Br J Surg 1991; 78: 777-781.
28. Popp MB, Hawley D, Reising J et al. Improved survival in squamous esophageal cancer. Preoperative chemotherapy and irradiation. Arch Surg 1986; 121: 1330-1335.
29. Postlethwait RW. Carcinoma of the thoracic esophagus. Surg Clin North Am 1983; 63: 933-940.
30. Pouliquen X, Levard H, Hay JM, Mc Gee K, Fingerhut A, Langlois-Zantin O, and the French Associations for Surgical Research. 5-Fluorouracil and Cisplatin therapy-after palliative surgical resection of squamous cell carcinoma of the oesophagus. A multicenter trial. Ann Surg 1966; 223: 127-133.
31. Roth A, Pass HI, Flanagan MM, Graeber GM, Rosenberg JC, Steinberg S. Randomized clinical trial of preoperative and postoperative adjuvant chemotherapy with Cisplatin, Vindesine and Bleomycin for carcinoma of the oesophagus. J Thorac Cardiovasc Surg 1988; 96: 242-248.
32. Saikia TK. Intermediate-dose methotrexate and cisplatin in the treatment of advanced epidermoid esophageal carcinoma. Response rate and disease-free survival. Cancer 1989; 64: 371-373.
33. Schwartz D, Flamant R, Lellouch J Clinical trials. London: Academic Press, 1980.
34. Scitz JF, Giovannini M, Padault-Cesana J et al. Inoperable non-metastatic squamous cell carcinoma of the oesophagus managed by concomitant chemotherapy (5 fluorouracil and cisplatin) and radiation therapy. Cancer 1990; 66: 214-219.
35. Shields W, Rosen ST, Hellerstein SM, Tsang TK, Ujiki GT, Kies MS. Multimodality approach to treatment of carcinoma of the oesophagus. Arch Surg 1984; 119: 558-562.
36. Skinner DB. Surgical treatment for esophageal carcinoma. Semin Oncol 1984; 11: 136-143.
37. Stewart FM, Harkins BJ, Hahn S, Daniel TM. Cisplatin, 5 fluorouracil, mitomycin C and concurrent radiation therapy with and without esophagectomy for esophageal carcinoma. Cancer 1989; 64: 622-628.
38. Ténière P, Hay JM, Fingerhut A, Fagniez PL, French University Association for Surgical Research. Post-operative radiation therapy does not increase survival after curative resection for squamous cell carcinoma of the middle and lower oesophagus as shown by a multicenter controlled trial. Surg Gynecol Obstet 1991; 173: 123-130.
39. Wara M, Mauch PM, Thomas AN, Philllips TL. Palliation for carcinoma of the esophagus. Radiology 1976; 121: 717-720.
40. Wu Y, Kuo-Chun H. Chinese experience in the surgical treatment of carcinoma of the esophagus. Ann Surg 1979; 190: 361-365.