Alterations of the MEN1 gene in sporadic parathyroid tumors

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 8, 1998, Pages 2627-2630

  Farnebo, Filip ^a   Teh, Bin Tean ^a   Kytölä, Soili ^b   Svensson, Ann ^a   Phelan, Catherine ^a   Sandelin, Kerstin ^a   Thompson, Norman W ^c   Höög, Anders ^a   Weber, Günther ^a   Farnebo, Lars Ove ^a   Larsson, Catharina ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN; PROTEIN MEN1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHROMOSOME 11Q; CLINICAL ARTICLE; FEMALE; GENE DELETION; GENE EXPRESSION; GENE INSERTION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MALE; MISSENSE MUTATION; MULTIPLE ENDOCRINE NEOPLASIA; NUCLEOTIDE SEQUENCE; PARATHYROID TUMOR; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; AUTORADIOGRAPHY; CHROMOSOMES, HUMAN, PAIR 11; FEMALE; HUMANS; IN SITU HYBRIDIZATION; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; MUTATION; PARATHYROID NEOPLASMS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RNA, MESSENGER;

EID: 15144346400     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.8.2627     Document Type: Article

References (17)

1. Horowitz JM, Yandell DW, Park SH, et al. 1989 Point mutational inactivation of the retinoblastoma antioncogene. Science. 243:937-940.
2. Latif F, Tory K, Gnarra J, et al. 1993 Identification of the von Hippel-Lindau disease tumor supressor gene. Science. 260:1317-1320.
3. Larsson C, Skogseid B, Öberg K, Nakamura Y, Nordenskjöld M. 1988 Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature. 332:85-87.
4. Chandrasekharappa SC, Guru SC, Manickam P, et al. 1997 Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science. 276:404-407.
5. The European Consortium on MEN1. 1997 Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. Hum Mol Genet. 6:1177-1183.
6. Agarwal SK, Kester MB, Debelenko LV, et al. 1997 Germline mutations of the MEN1 gene in familial endocrine neoplasia type 1 and related states. Hum Mol Genet. 6:1169-1175.
7. Teh BT, Zedenius J, Kytölä S, et al. Thymic carcinoids in multiple endocrine neoplasia type 1. Ann Surg. In press.
8. Thakker RV, Bouloux P, Wooding C, et al. 1989 Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11. N Engl J Med. 318:658-662.
9. Byström C, Larsson C, Blomberg C, et al. 1990 Localization of the MEN1 gene within a small region of 11q13 by deletion mapping in tumors. Proc Natl Acad Sci USA. 87:1968-1972.
10. Friedman E, De Marco L, Gejman P, et al. 1992 Allelic loss from chromosome 11 in parathyroid tumors. Cancer Res. 52:6804-6809.
11. Heppner C, Kester MB, Agarwal SK, et al. 1997 Somatic mutations of the MEN1 gene in parathyroid tumors. Nat Genet. 16:375-378.
12. Olson Jr JA, DeBenedetti MK, Baumann DS, Wells Jr SA. 1996 Parathyroid autotransplantation during thyroidectomy. Results of long-term follow-up. Ann Surg. 223:472-478.
13. Farnebo F, Enberg U, Grimelius L, et al. 1997 Tumor specific decreased expression of the calcium sensing receptor (CaR) mRNA in sporadic primary hyperparathyroidism. J Clin Endocrinol Metab. 82:3481-3486.
14. The European Consortium on MEN. 1 1997 Construction of a 1.2 Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene. Genomics. 44:94-100.
15. Tokunaga K, Nakamura Y, Sakata K, et al. 1987 Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res. 47:5616-5619.
16. Gailani MR, Ståhle-Bäckdahl M, Leffell DJ, et al. 1997 The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nat Genet. 14:78-81.
17. Luan X, Shi G, Zohouri M, et al. 1997 The FHIT gene is alternatively spliced in normal and renal cell carcinoma. Oncogene. 15:79-86.