Role of endothelium and K+ channels in dobutamine-induced relaxation in rat mesenteric artery

Clinical and Experimental Pharmacology and Physiology

Volumn 25, Issue 6, 1998, Pages 405-411

  Huang, Yu ^a,b   Kwok, Kai Hong ^a   Chan, Nickie Wai Kei ^a   Lau, Chi Wai ^a   Chen, Zhen Yu ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Dobutamine; Endothelium; K+ channel; Rat mesenteric artery; Relaxation; Tetrapentylammonium; Adrenoceptor

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; BETA ADRENERGIC RECEPTOR; CHARYBDOTOXIN; DOBUTAMINE; FORSKOLIN; IBERIOTOXIN; INDOMETACIN; METHYLENE BLUE; N(G) NITRO DEXTRO ARGININE; N(G) NITROARGININE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; POTASSIUM CHANNEL; PROSTACYCLIN; TETRAPENTYLAMMONIUM; TETRYLAMMONIUM;

ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; DRUG ANTAGONISM; DRUG INHIBITION; MALE; MESENTERIC ARTERY; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; RAT; VASODILATATION;

EID: 15144343818     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1998.tb02223.x     Document Type: Article

References (35)

1. Rasmussen H. The calcium messenger system. N. Engl. J. Med. 1986; 314: 1094-101.
2. Rubanyi G, Vanhoutte PM. Endothelium removal decreases relaxations of canine coronary arteries caused by β-adrenergic agonists and adenosine. J. Cardiovasc. Pharmacol. 1985; 7: 139-44.
3. Kamata K, Miyata N, Kasura Y. Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats. J. Pharmacol. Exp. Ther. 1989; 249: 890-4.
4. Gray DW, Marshall I. Novel signal transduction pathway mediating endothelium-dependent β-adrenoceptor vasorelaxation in rat thoracic aorta. Br. J. Pharmacol. 1992; 107: 684-90.
5. Grace GC, MacDonald PS, Dusting GJ. Cyclic nucleotide interactions involved in endothelium-dependent dilatation in rat aortic rings. Eur. J. Pharmacol. 1988; 148: 17-24.
6. Martin W, Villani GM, Jothianandan D, Furchgott RF. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J. Pharmacol. Exp. Ther. 1985; 232: 708-16.
7. Moncada S, Rees DD, Schultz R, Palmer RMJ. Development and mechanisms of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthase in vivo. Proc. Natl Acad. Sci. USA 1991; 88: 2166-70.
8. Konishi M, Su C. Role of the endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension 1983; 5: 881-6.
9. Ba ML, Ghaleh B, Giudicelli JF, Berdeaux A. Lack of importance of NO in β-adrenoceptor-mediated relaxation in large epicardial canine coronary arteries. Br. J. Pharmacol. 1994; 111: 981-2.
10. Nelson MT, Patlak JB, Worley JF, Standen NB. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am. J. Physiol. 1990; 259: C3-18.
11. Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 1995; 268: C799-822.
12. 2-adrenoceptor activation in rat aortic rings. Br. J. Pharmacol. 1996; 119: 505-10.
13. + channel blockers on β-adrenoceptor-mediated vasorelaxation of rat mesenteric artery. J. Cardiovasc. Pharmacol. 1997; 29: 515-19.
14. + channels in smooth muscle cells from basilar artery of guinea pig. Pfl gers Arch. 1995; 430: 984-93.
15. Randall MD, McCulloch AI. The involvement of ATP-sensitive potassium channels in β-adrenoceptor-mediated vasorelaxation in the rat isolated mesenteric arterial bed. Br. J. Pharmacol. 1995; 115: 607-12.
16. 1-adrenoceptor stimulation in dog. Am. J. Physiol. 1994; 266: H84-92.
17. Hsken BCP, Pfaffendorf M, van Zweiten PA. The influence of glucose and glibenclamide on vascular β-adrenoceptor-mediated responses. Br. J. Pharmacol. 1994; 112: P214.
18. Hsken BCP, Pfaffendorf M, van Zweiten PA. Contribution of ATP-sensitive potassium channels to β-adrenoceptor-mediated responses. Naunyn Schmiedebergs Arch. Pharmacol. 1997; 355: 97-102.
19. Nakashima M, Vanhoutte PM. Isoprenaline causes hyperpolarization through opening of ATP-sensitive potassium channels in vascular smooth muscle of the canine saphenous vein. J. Pharmacol. Exp. Ther. 1995; 272: 379-84.
20. O'Donnell SR, Wanstall JC. Beta-1 and beta-2 adrenoceptor-mediated responses in preparations of pulmonary artery and aorta from young and aged rats. J. Pharmacol. Exp. Ther. 1984; 228: 733-8.
21. Macdonald PS, Dubbin PN, Dusting GJ. β-Adrenoceptors on endothelial cells do not influence release of relaxing factor in dog coronary arteries. Clin. Exp. Pharmacol. Physiol. 1987; 14: 525-34.
22. Graves J, Poston L. β-Adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: A role for the endothelium and nitric oxide. Br. J. Pharmacol. 1993; 108: 631-7.
23. 2-adrenoceptors. Eur. J. Pharmacol. 1986; 130: 137-9.
24. 2-selective adrenoceptor antagonist (ICI 118 551). J. Cardiovasc. Pharmacol. 1983; 5: 430-7.
25. Stephenson JA, Summers RJ. Autoradiographic analysis of receptors on vascular endothelium. Eur. J. Pharmacol. 1988; 134: 35-43.
26. Molenaar P, Malta E, Jones CR, Buxton BR, Summers RJ. Autoradiographic localisation and function of β-adrenoceptors on the human internal mammary artery and saphenous vein. Br. J. Pharmacol. 1988; 95: 225-33.
27. Kuhn M, Otten A, Frolich JC, Forstermann U. Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells. J. Pharmacol. Exp. Ther. 1991; 256: 677-82.
28. + channels in arterial smooth muscle. Science 1989; 245: 177-80.
29. Brayden JE. Membrane hyperpolarization is a mechanism of endothelium-dependent cerebral vasodilation. Am. J. Physiol. 1990; 259: H668-73.
30. + channels. Nature 1990; 344: 770-3.
31. Archer SL, Huang JM, Hampl V, Nelson DP, Schultz PJ, Weir EK. Nitric oxide and cGMPcause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc. Natl Acad. Sci. USA 1994; 91: 7583-7.
32. + channels. J. Physiol. 1995; 486: 47-58.
33. + efflux. Naunyn Schmiedebergs Arch. Pharmacol. 1989; 337 (Suppl.): R64 (Abstract).
34. + channels by tetrapentylammonium ions. Circulation 1990; 82: III-134 (Abstract).
35. Langton PD, Nelson MT, Huang Y, Standen NB. Block of calcium-activated potassium channels in mammalian arterial myocytes by tetraethylammonium ions. Am. J. Physiol. 1991; 260: H927-34.