Challenging dose-response dogma

Scientist

Volumn 19, Issue 3, 2005, Pages 22-23

  Calabrese, Edward J ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; CARCINOGEN; LEAD; MERCURY; TOXIN;

ARTICLE; CANCER RISK; DOSE RESPONSE; GOVERNMENT; HOMEOPATHY; HORMESIS; HUMAN; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; NONHUMAN; PUBLIC HEALTH; RISK ASSESSMENT; SAFETY;

EID: 15044365178     PISSN: 08903670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. E.J. Calabrese, L.A. Baldwin, "Toxicology rethinks its central belief - Hormesis demands a reappraisal of the way risks are assessed," Nature, 421:691-2, 2003.
2. E.J. Calabrese, "Hormesis: from marginalization to mainstream. A case for hormesis as the default dose-response model in risk assessment," Toxicol Appl Pharm, 197:125-36, 2004.
3. E.J. Calabrese, L.A. Baldwin, "Hormesis: U-shaped dose-response and their centrality in toxicology," Trends Pharmacol Sci, 22:285-91, 2001.
4. T. Sukata et al., "Detailed low-dose study of 1,1-B IS(p-chlorophenyl)-2,2,2-trichloroethane carcinogenesis suggests the possibility of a hormetic effect." Int J Cancer, 99:112-8, 2002.
5. E.J. Calabrese, R. Blain, "The hormesis database: an overview," Toxicol Appl Pharm. 2005, in press.