Properties of average-conductance cationic channels that mediate cholinergic excitation of guinea-pig ileum myocytes under conditions close to the physiological norm

Neurophysiology

Volumn 36, Issue 4, 2004, Pages 247-253

  Dresvyannikov, A V ^a   Zholos, A V ^a   Shuba, M F ^a  

^a BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

Author keywords

Carbachol; GTP S; Guinea pig ileum; M receptors; Myocytes; Unitary cationic channels

Indexed keywords

CALCIUM ION; CATION CHANNEL; CESIUM; DIVALENT CATION; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MAGNESIUM ION; SODIUM;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHOLINERGIC STIMULATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTRIC CONDUCTIVITY; GUINEA PIG; ILEUM; ION CURRENT; MUSCLE CELL; NONHUMAN; NORMAL VALUE; PATCH CLAMP; PIPETTE; PROBABILITY; PROTEIN STABILITY; SMOOTH MUSCLE FIBER;

EID: 15044357731     PISSN: 00902977     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11062-004-0003-1     Document Type: Article

References (17)

1. R. Inoue and G. Isenberg, "Acetylcholine activates nonselective cation channels in guinea pig ileum through a G protein," Am. J. Physiol., 258, Part 1, 1173-1178 (1990).
2. H. D. Yan, H. Okamoto, T. Unno, et al., "Effects of G-protein-specific antibodies and G beta gamma subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells," Br. J. Pharmacol., 139, 605-615 (2003).
3. S. Komori and T. B. Bolton, "Calcium release induced by inositol 1,4,5-trisphosphate in single rabbit intestinal smooth muscle cells," J. Physiol., 433, 495-517 (1991).
4. A. V. Zholos and T. B. Bolton, "Effects of protons on muscarinic receptor cationic current in single visceral smooth muscle cells," Am. J. Physiol., 272, Part 1, 215-223 (1997).
5. A. V. Zholos and T. B. Bolton, "Effects of divalent cations on muscarinic receptor cationic current in smooth muscle from guinea-pig small intestine," J. Physiol., 486, Part 1, 67-82 (1995).
6. A. V. Zholos and T. B. Bolton, " novel GTP-dependent mechanism of ileal muscarinic metabotropic channel desensitization," Br. J. Pharmacol., 119, 997-1012 (1996).
7. H. Akbulut, Z. Goren, E. Iskender, et al., "Subtypes of muscarinic receptors in rat duodenum: A comparison with rabbit vas deferens, rat atria, guinea-pig ileum and gallbladder by using imperialine," Gen. Pharmacol., 32, 505-511 (1999).
8. L. V. Baidan, A. V. Zholos, and J. D. Wood, "Modulation of calcium currents by G-proteins and adenosine receptors in myenteric neurons cultured from adult guinea-pig small intestine" Br. J. Pharmacol., 116, 1882-1886 (1995).
9. T. B. Bolton and A. V. Zholos, "Activation of M2 muscarinic receptors in guinea-pig ileum opens cationic channels modulated by M3 muscarinic receptors," Life Sci., 60, 1121-1128 (1997).
10. S. Chen, R. Inoue, and Y. Ito, "Pharmacological characterization of muscarinic receptor-activated cation channels in guinea-pig ileum," Br. J. Pharmacol., 109, 793-801 (1993).
11. R. Inoue, H. Morita, H. Yanagida, et al., "Potentiating actions of lanthanum on ACh-induced cation current in guinea-pig ileal smooth muscle cells," J. Smooth Muscle Res., 34, 69-81 (1998).
12. A. V. Zholos and T. B. Bolton, "Muscarinic receptor subtypes controlling the cationic current in guinea-pig ileal smooth muscle," Br. J. Pharmacol., 122, 885-893 (1997).
13. K. Loffelholz, "Muscarinic receptors and cell signaling," Prog. Brain Res., 109, 191-194 (1996).
14. S. A. Prestwich and T. B. Bolton, "G-protein involvement in muscarinic receptor-stimulation of inositol phosphates in longitudinal smooth muscle from the small intestine of the guinea-pig," Br. J. Pharmacol., 114, 119-126 (1995).
15. J. C. Rhee, P. L. Rhee, M. K. Park, et al., "Muscarinic receptors controlling the carbachol-activated nonselective cationic current in guinea pig gastric smooth muscle cells," Jpn. J. Pharmacol., 82, 331-337 (2000).
16. T. Unno, S. C. Kwon, H. Okamoto, et al., "Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle," Br. J. Pharmacol., 139, 337-350 (2003).
17. A. V. Zholos, A. A. Zholos, and T. B. Bolton," G-protein-gated TRP-like cationic channel activated by muscarinic receptors: Effect of potential on single-channel gating," J. Gen. Physiol., 123, 581-598 (2004).