Asymmetric synthesis of novel tetrahydroquinoline derivatives with a sugar building block and their bioactivities

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 7, 2005, Pages 1821-1824

  Liu, Hong Min ^a   Liu, Feng Wu ^a   Zou, Da Peng ^a   Dai, Gui Fu ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Asymmetric synthesis; Bioactivity; Building block; Carbohydrates; Tetrahydroquinoline

Indexed keywords

QUINOLINE DERIVATIVE; SUCROSE;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; STEREOCHEMISTRY;

EID: 15044349585     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.024     Document Type: Article

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29. x, BIO-TEK INSTRUMENT, INC), respectively. OD values were achieved by subtracting the absorbance at 630 nm from the 570 nm absorbance
30. 3 cells/well). The next day test substances were freshly dissolved in DMSO resulting in 10 mg/mL stock solutions. Stock solutions were diluted in culture medium and added (200 μL/well) at various concentrations to the wells, resulting in seven final concentrations between 1 and 100 μg/mL. 48 or 72 h later the MTT-test was performed