Phase II study of oral S-1 plus irinotecan in patients with advanced colorectal cancer: Hokkaido Gastrointestinal Cancer Study Group HGCSG0302

Japanese Journal of Clinical Oncology

Volumn 35, Issue 2, 2005, Pages 88-89

  Komatsu, Yoshito ^a   Yuuki, Satoshi ^a   Fuse, Nozomu ^a   Takei, Masaaki ^a   Kato, Takashi ^a   Miyagishima, Takuto ^a   Kudo, Mineo ^a   Kunieda, Yasuyuki ^a   Tateyama, Miki ^a   Wakahama, Osamu ^a   Meguro, Takashi ^a   Ohizumi, Hiroko ^a   Watanabe, Maso ^a   Akita, Hirotoshi ^a   Sakata, Yu ^b   Asaka, Masahiro ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Misawa City Hospital   (Japan)

Author keywords

Colorectal cancer; Irinotecan; Phase II study; S 1

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; IRINOTECAN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DRUG DERIVATIVE; OXONIC ACID; PYRIDINE DERIVATIVE; S 1 (COMBINATION); TEGAFUR;

ADVANCED CANCER; ARTICLE; BLOOD TOXICITY; CANCER CENTER; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; COLORECTAL CANCER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DISEASE COURSE; DRUG EFFICACY; DRUG SAFETY; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPAN; NEUTROPENIA; OPEN STUDY; OUTPATIENT CARE; PHASE 2 CLINICAL TRIAL; TREATMENT PLANNING; ADENOCARCINOMA; ADOLESCENT; ADULT; AGED; AMBULATORY CARE; COLORECTAL TUMOR; DRUG ADMINISTRATION; DRUG COMBINATION; MIDDLE AGED; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION;

ADENOCARCINOMA; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; AMBULATORY CARE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; COLORECTAL NEOPLASMS; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; HUMANS; MIDDLE AGED; OXONIC ACID; PYRIDINES; TEGAFUR;

EID: 15044344582     PISSN: 03682811     EISSN: None     Source Type: Journal    
DOI: 10.1093/jjco/hyi025     Document Type: Article

References (4)

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2. Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer. Lancet 2000;25:1041-7.
3. Komatsu Y, Takeda H, Takei M, Kato T, Tateyama M, Miyagishima T. A phase I and PK study of S-1 and irinotecan (CPT-11) in patients with advanced gastric cancer (AGC). Proc Am Soc Clin Oncol 2002;21:171 (abstract 683).
4. Wasserman E, Myara A, Lokiec F, Goldwasser F, Trivun F, Mahjoubi M. Severe CPT-11 toxicity in patients with Gilbert's syndrome: two case reports. Ann Oncol 1997;8:1049-51.