Value of C-reactive protein levels and IL-6 in predicting events levels in women at increased cardiovascular risk

Maturitas

Volumn 50, Issue 4, 2005, Pages 239-246

  Vitale, Cristiana ^c   Gebara, Otavio ^a   Mercuro, Giuseppe ^b   Wajngarten, Mauricio ^c   Silvestri, Antonello ^c   Rossini, Paola ^c   Ramires, Josè Antonio ^a   Fini, Massimo ^c   Rosano, Giuseppe M C ^c  

^a Cardiovascular Research Unit   (Italy)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Atherosclerosis; Hormone replacement therapy; Inflammation

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; INTERLEUKIN 6;

AGED; ARTICLE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR RISK; CARDIOVASCULAR SYMPTOM; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEALTH STATUS; HORMONE SUBSTITUTION; HUMAN; MULTIVARIATE ANALYSIS; OUTPATIENT; POSTMENOPAUSE; PROTEIN BLOOD LEVEL; TRANSIENT ISCHEMIC ATTACK; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT OUTCOME; UNSTABLE ANGINA PECTORIS;

ANGINA;

EID: 14944377919     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2003.09.032     Document Type: Article

References (29)

1. Barrett-Connor E., Grady D. Hormone replacement therapy, heart disease, and other considerations. Annu. Rev. Public Health. 19:1998;55-72
2. Marchien van Baal W., Kenemans P., Emeis J.J., Schalkwijk C.G., Mijatovic V., van der Mooren M.J., et al. Long-term effects of combined hormone replacement therapy on markers of endothelial function and inflammatory activity in healthy postmenopausal women. Fertil. Steril. 71:1999;663-670
3. Hulley S., Grady D., Bush T., Furberg C., Herrington D., Riggs B., et al. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA. 280:1998;605-613
4. Ridker P.M., Hennekens C.H., Rifai N., Buring J.E., Manson J.E. Hormone replacement therapy and increased plasma concentration of C-reactive protein. Circulation. 100:1999;713-716
5. Cushman M., Legault C., Barrett-Connor E., Stefanick M.L., Kessler C., Judd H.L. Effect of postmenopausal hormones on inflammation-sensitive proteins the postmenopausal estrogen/progestin interventions (PEPI) study. Circulation. 100:1999;717-722
6. Danesh J., Whineup P., Walker M., Lennon L., Thomson A., Appleby P., et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. BMJ. 321:2000;199-204
7. Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., Hennekens C.H. Inflammation, aspirin and the risk of cardiovascular disease in apparently healthy men. N. Engl. J. Med. 340:1999;115-126
8. Ridker P.M., Glynn R.J., Hennekens C.H. C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation. 97:1998;2007-2011
9. Bermudez E.A., Rifai N., Buring J., Manson J.E., Ridker P.M. Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women. Arterioscler. Thromb. Vasc. Biol. 22(10):2002;1668-1673
10. Baumann H., Gauldie J. The acute phase response. Immunol. Today. 25:1994;74-80
11. De Maat M.P., Pietersma A., Kofflard M., Sluiter W., Kluft C. Association of plasma fibrinogen levels with coronary artery disease, smoking and inflammatory markers. Atherosclerosis. 121:1996;185-191
12. Ikeda U., Ito T., Shimada K. Interleukin-6 and acute coronary syndrome. Clin. Cardiol. 24(11):2001;701-704
13. Straub R.H., Hense H.W., Andus T., Schölmerich J., Riegger G.A.J., Schunkert H. Hormone replacement therapy and interrelation between serum interleukin-6 and body mass index in postmenopausal women: a population-based study. J Clin Endocrinol Metabol. 85(3):2000;1340-1344
14. Wood D., De Backer G., Faergeman O. Prevention of coronary heart disease in clinical practice. Recommendations of the second Joint Task Force of European and other Societies on Coronary Prevention. Eur. Heart J. 19:1998;1434-1503
15. Pradhan A.D., Manson J.E., Rossouw J.E., Siscovick D.S., Mouton C.P., Rifai N., et al. Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study. JAMA. 288(8):2002;980-987
16. Ross R. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340:1999;115-126
17. Libby P., Ridker P.M., Maseri A. Inflammation and atherosclerosis. Circulation. 105:2002;1135-1143
18. Yeh E.T.H., Anderson V., Pasceri V., Willerson J.T. C-reactive protein linking inflammation to cardiovascular complications. Circulation. 104:2001;974-975
19. Volpato S, Guralnik JM, Ferrucci L, Balfour J, Chaves P, Fried LP, Harris TB. Cardiovascular disease, interleukin-6, and risk of mortality in older women the women's health and aging study. Circulation 2001;103:947.
20. Garcia-Moll X., Zouridakis E., Cole D., Kaski J.C. C-reactive protein in patients with chronic stable angina: differences in baseline serum concentration between women and men. Eur. Heart J. 21:2000;1598-1606
21. Wilcox J.G., Hatch I.E., Gentzschein E., Stanczyk F.Z., Lobo R.A. Endothelin levels decrease after oral and non-oral estrogen in postmenopausal women with increased cardiovascular risk factors. Fertil. Steril. 67:1997;273-277
22. Baumann H., Gauldie J. Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation. Mol. Biol. Med. 7:1990;147-159
23. Biasucci LM, Vitelli A, Liuzzo G, Altamura S, Caligiuri G, Monaco C, Rebuzzi AG, Ciliberto G, Elevated Levels of Interleukin-6 in Unstable Angina. Circulation 1996;94:874-7.
24. Le J., Vilcek J. Interleukin 6: a multifunctional cytokine regulating immune reactions and the acute phase protein sequence. Lab. Invest. 61:1989;588-602
25. Fuster V., Badimon L., Badimon J., Chesebro J.H. The pathogenesis of coronary artery disease and the acute coronary syndromes. N. Engl. J. Med. 326:1992;310-318
26. Sturk A., Hack C.E., Aarden L.A., Mieke B., Koster R.R.W., Sanders G.T.B. Interleukin-6 release and the acute-phase reaction in patients with acute myocardial infarction: a pilot study. J. Lab. Clin. Med. 119:1992;574-579
27. Cioffi M., Esposito K., Vietri M.T., Gazzerro P., D'Auria A., Ardovino I., et al. Cytokine pattern in postmenopause. Maturitas. 41(3):2002;187-192
28. Saucedo R., Rico G., Basurto L., Ochoa R., Zarate A. Transdermal estradiol in menopausal women depresses interleukin-6 without affecting other markers of immune response. Gynecol. Obstet. Invest. 53(2):2002;114-117
29. Silvestri A., Gebara O., Vitale C., Wajngarten M., Leonardo F., Ramires J.A., et al. Increased levels of C-reactive protein after oral hormone replacement therapy may not be related to an increased inflammatory response. Circulation. 107(25):2003;3165-3169