Artecoll: A long-lasting injectable wrinkle filler material: Report of a controlled, randomized, multicenter clinical trial of 251 subjects

Plastic and Reconstructive Surgery

Volumn 114, Issue 4, 2004, Pages 964-976

  Cohen, Steven R ^a,b,c   Holmes, Ralph E ^a,b,c  

^a University of California ^*  (United States)

^b Departments of Cognitive Science and Neurosciences   (United States)

^c Artes Medical   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN IMPLANT; FILLER; IMMUNOGLOBULIN G; MICROSPHERE; POLY(METHYL METHACRYLATE); ARTECOLL; COLLAGEN; DRUG DERIVATIVE;

ABSCESS; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EDEMA; ERYTHEMA; FEMALE; FLU LIKE SYNDROME; FOOD AND DRUG ADMINISTRATION; GRANULOMA; HERPES LABIALIS; HUMAN; HYPERSENSITIVITY; IMMUNOGLOBULIN BLOOD LEVEL; INFECTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; UNITED STATES; VISUAL IMPAIRMENT; WRINKLE; COMPARATIVE STUDY; ESTHETICS; FOLLOW UP; MIDDLE AGED; PATIENT SATISFACTION; RHYTIDOPLASTY; SAFETY; SUBCUTANEOUS DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; COLLAGEN; DEVICE APPROVAL; ESTHETICS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, SUBCUTANEOUS; MALE; MIDDLE AGED; PATIENT SATISFACTION; POLYMETHYL METHACRYLATE; RHYTIDOPLASTY; TREATMENT OUTCOME;

EID: 14944360075     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000133169.16467.5F     Document Type: Article

References (16)

1. Alster, T. S., and West, T. B. Human-derived and new synthetic injectable materials for soft-tissue augmentation: Current status and role in cosmetic surgery. Plast. Reconstr. Surg. 105: 2515, 2000.
2. Kinney, B. M., and Hughes, C. E., III. Soft tissue fillers: An overview. Aesthetic Surg. J. 21: 469, 2001.
3. Rubin, J. P., and Yaremchuk, M. J. Complications and toxicities of implantable biomaterials used in facial reconstructive and aesthetic surgery: A comprehensive review of the literature. Plast. Reconstr. Surg. 100: 1, 1997.
4. Lemperle, G., Romano, J. J., and Busso, M. Soft tissue augmentation with Artecoll: 10-year history, indications, technique, and potential side effects. Dermatol. Surg. 29: 573, 2003.
5. Lemperle, G., Holmes, R. E., Cohen, S. R., and Lemperle, S. M. A classification of facial wrinkles. Plast. Reconstr. Surg. 108: 1736, 2001.
6. Tan, C. Y., Statham, B., Marks, R., and Payne, P. A. Skin thickness measurement by pulses ultrasound: Its reproducibility, validation, and variability. Br. J. Dermatol. 106: 675, 1982.
7. Knapp, T. R., Kaplan, E. N., and Daniels, J. R. Injectable collagen for soft-tissue augmentation. Plast. Reconstr. Surg. 60: 398, 1977.
8. Lemperle, G., Hazan-Gauthier, N., and Lemperle, M. PMMA microspheres (Artecoll) for skin and soft-tissue augmentation: Part II. Clinical investigations. Plast. Reconstr. Surg. 96: 627, 1995.
9. Lemperle, G., Ott, H., Charrier, U., Hecker, J., and Lemperle, M. PMMA microspheres for intradermal implantation: Part I. Animal research. Ann. Plast. Surg. 26: 57, 1991.
10. McClelland, M., Egbert, B., Hanko, V., Berg, R. A., and DeLustro, F. Evaluation of Artecoll polymethylmethacrylate implant for soft-tissue augmentation: Biocompatibility and chemical characterization. Plast. Reconstr. Surg. 100: 1466, 1997.
11. Judet, J. Protheses en resins acrylic. Mem. Acad. Chir. 73: 561, 1947.
12. Morhenn, V. B., Lemperle, G., and Gallo, R. L. Phagocytosis of different particulate dermal filler substances by human macrophages and skin cells. Dermatol. Surg. 28: 484, 2002.
13. Lemperle, G., Morhenn, V. B., Pestonjamasp, V., and Gallo, R. L. Migration studies and histology of injectable microspheres of different sizes in mice. Plast. Reconstr. Surg. 113: 1380, 2004.
14. Lemperle, G., Morhenn, V. B., and Charrier, U. Human histology and persistence of various injectable filler substances for soft tissue augmentation. Dermatol. Surg. 28: 484, 2002.
15. Requena, C., Izquierdo, M. J., Navarro, M., et al. Adverse reactions to injectable aesthetic microimplants. Am. J. Dermatopathol. 23: 197, 2000.
16. Manuskiatti, W., and Fitzpatrick, R. E. Treatment response of keloidal and hypertrophic sternotomy scars: Comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. Arch. Dermatol. 138: 1149, 2002.