Editorial overview: Maternal thyrotropin receptor-blocking antibodies and the fetus: Current perspectives

Current Opinion in Endocrinology and Diabetes

Volumn 12, Issue 1, 2005, Pages 1-3

  Brown, Rosalind S ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MATERNAL ANTIBODY; THYROTROPIN RECEPTOR; THYROTROPIN RECEPTOR ANTIBODY;

BRAIN DEVELOPMENT; EDITORIAL; FETUS DEVELOPMENT; HUMAN; HYPOTHYROIDISM; PREGNANCY; THYROID GLAND; THYROTROPIN RELEASE; TRANSCRIPTION REGULATION;

EID: 14944350856     PISSN: 10683097     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.med.0000152668.83803.e7     Document Type: Editorial

References (15)

1. Blizzard RM, Chandler RW, Landing BH, et al. Maternal autoimmunization to thyroid as a probable cause of athyrotic cretinism. N Engl J Med 1960; 263:327-336.
2. Matsuura N, Konishi J, Harada S, et al. The prediction of thyroid function in infants born to mothers with chronic thyroiditis. Endocrinol Jpn 1989; 36:865-871.
3. Brown RS, Bellisario RL, Botero D, et al. Incidence of transient congenital hypothyroidism due to maternal thyrotropin receptor-blocking antibodies in over one million babies. J Clin Endocrinol Metab 1996; 81:1147-1151.
4. Baker JR Jr: Dissecting the immune response to the thyrotropin receptor in autoimmune thyroid disease. J Clin Endocrinol Metab 1993; 77:16-18.
5. Evans C, Jordan NJ, Owens G, et al. Potent thyrotrophin receptor-blocking antibodies: a cause of transient congenital hypothyroidism and delayed thyroid development. Eur J Endocrinol 2004; 150:265-268.
6. Brown RS, Shalhoub V, Coulter S, et al. Developmental regulation of thyrotropin receptor gene expression in the fetal and neonatal rat thyroid: relation to thyroid morphology and to thyroid-specific gene expression. Endocrinology 2000; 141:340-345.
7. Beamer WG, Cresswell LA: Defective thyroid ontogenesis in fetal hypothyroid (hyt/hyt) mice. Anat Rec 1982; 202:387-393.
8. Biebermann H, Schoneberg T, Krude H, et al. Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism. J Clin Endocrinol Metab 1997; 82:3471-3480.
9. McKenzie JM, Zakarija M: Fetal and neonatal hyperthyroidism and hypothyroidism due to maternal TSH receptor antibodies. Thyroid 1992; 2:155-159.
10. Radetti G, Persani L, Moroder W, et al. Transplacental passage of anti-thyroid auto-antibodies in a pregnant woman with auto-immune thyroid disease. Prenat Diagn 1999; 19:468-471.
11. Kung AW, Jones BM: A change from stimulatory to blocking antibody activity in Graves' disease during pregnancy. J Clin Endocrinol Metab 1998; 83: 514-518.
12. Kung AW, Lau KS, Kohn LD: Epitope mapping of TSH receptor-blocking antibodies in Graves' disease that appear during pregnancy. J Clin Endocrinol Metab 2001; 86:3647-3653.
13. Utiger RD: Vanishing hypothyroidism. N Engl J Med 1992; 326:562-563.
14. Chazenbalk GD, Pichurin P, Chen CR, et al. Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor. J Clin Invest 2002; 110:209-217.
15. Matsuura N, Konishi J: Transient hypothyroidism in infants born to mothers with chronic thyroiditis: a nationwide study of twenty-three cases. The Transient Hypothyroidism Study Group. Endocrinol Jpn 1990; 37:369-379.