Surface modification of poly(ether urethane urea) with modified dehydroepiandrosterone for improved in vivo biostability

Journal of Biomedical Materials Research - Part A

Volumn 73, Issue 1, 2005, Pages 108-115

  Christenson, Elizabeth M ^a   Wiggins, Michael J ^a   Anderson, James M ^a,b   Hiltner, Anne ^a  

^a Case Western Reserve University   (United States)

^b Case Western Reserve University   (United States)

Author keywords

Biodegradation; Dehydroepiandrosterone; in vivo; Poly(ether urethane); Surface modification

Indexed keywords

ADDITIVES; ATTENUATION; CHEMICAL MODIFICATION; DEGRADATION; DERIVATIVES; FATTY ACIDS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; ION IMPLANTATION; OPTICAL MICROSCOPY; POLYURETHANES; SOLUBILITY; SURFACE CHEMISTRY; SURFACE TREATMENT; SYNTHESIS (CHEMICAL);

BIOSTABILITY; DEHYDROEPIANDROSTERONE (DHEA); POLYURETHANE ADDITIVES; POLYURETHANE FILMS;

UREA;

BIOMATERIAL; CRYSTALLIN; POLY(ETHER URETHANE UREA); POLYMER; PRASTERONE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; BIODEGRADATION; CELL ACTIVITY; CHEMICAL MODIFICATION; DOWN REGULATION; FILM; IMPLANT; INFRARED SPECTROSCOPY; MACROPHAGE; MATERIAL COATING; MICROSCOPY; NONHUMAN; RAT; SURFACE PROPERTY; SYNTHESIS;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; DEHYDROEPIANDROSTERONE; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; POLYURETHANES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 14844360820     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.30271     Document Type: Article

References (19)

1. Gogolewski S. In vitro and in vivo molecular stability of medical polyurethanes: A review. Trends Polym Sci 1991;1:47-61.
2. Stokes K, McVenes R. Polyurethane elastomer biostability. J Biomater Appl 1995;9:321-354.
3. Szycher M, Reed A. Biostable polyurethane elastomers. Med Device Technol 1992;3:42-51.
4. Zhao Q, Agger M, Fitzpatrick M, Anderson J, Hiltner A, Stokes K, Urbanski P. Cellular interactions with biomaterials: In vivo cracking of pre-stressed Pellethane 2363-80A. J Biomed Mater Res 1990;24:621-637.
5. Lelah M, Cooper S. Polyurethanes in medicine. Boca Raton, FL: CRC Press; 1986.
6. Zhao Q, Topham N, Anderson J, Hiltner A, Lodoen G, Payet C. Foreign-body giant cells and polyurethane biostability: In vivo correlation of cell adhesion and surface cracking. J Biomed Mater Res 1991;25:177-183.
7. Wu Y, Sellitti C, Anderson J, Hiltner A, Lodoen G, Payet C. An FTIR-ATR investigation of in vivo poly(ether urethane) degradation. J Appl Polym Sci 1992;46:201-211.
8. Schubert M, Wiggins M, Schaefer M, Hiltner A, Anderson J. Oxidative biodegradation mechanisms of biaxially strained poly(ether urethane urea) elastomers. J Biomed Mater Res 1995;29:337-347.
9. Schubert M, Wiggins M, Hiltner A, Anderson J. Role of oxygen in biodegradation of poly(ether urethane urea) elastomers. J Biomed Mater Res 1997;34:519-530.
10. Szycher M. Biostability of polyurethane elastomers: A critical review. J Biomed Appl 1988;3:297-401.
11. Schubert M, Wiggins M, Anderson J, Hiltner A. Comparison of two antioxidants for poly(ether urethane urea) in an accelerated in vitro biodegradation system. J Biomed Mater Res 1997;34:493-505.
12. Renier M, Wu Y, Anderson J, Hiltner A, Lodoen G, Payet C. Characterization of extractable species from poly(etherurethane urea) (PEUU) elastomers. J Biomed Mater Res 1994;5:511-529.
13. Araghiniknam M, Chung S, Nelson-White T, Eskelson C, Watson R. Antioxidant activity of dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sci 1996;59:147-157.
14. Rom W, Harkin T. Dehydroepiandrosterone inhibits the spontaneous release of superoxide radical by alveolar macrophages in vitro in asbestosis. Environ Res 1991;55:145-150.
15. Loria R, Padgett D, Huynh P. Regulation of the immune response by dehydroepiandrosterone and its metabolites. J Endocrinol 1996;150:S209-S220.
16. Uozumi K, Uematsu T, Otsuka M, Nakano S, Takatsuka Y, Iwahashi M, Hanada S, Arima T. Serum dehydroepiandrosterone and DHEA-sulfate in patients with adult T-cell leukemia and human T-lymphotropic virus type I carriers. Am J Hematol 1996;53:165-168.
17. Skolnick A. Scientific verdict still out on DHEA. JAMA 1996;276:1365-1367.
18. Collier T, Tan J, Shive M, Hasan S, Hiltner A, Anderson J. Biostability of poly(ether urethane urea) containing dehydroepiandrosterone. J Biomed Mater Res 1998;41:192-201.
19. Tanzi M, Maritovani D, Petrini P, Guidoin R, Laroche G. Chemical stability of poly(ether urethanes) versus poly(carbonate urethanes). J Biomed Mater Res 1997;36:550-559.