Pharmacokinetics of azithromycin after intravenous and intramuscular administration to goats

Journal of Veterinary Pharmacology and Therapeutics

Volumn 28, Issue 1, 2005, Pages 51-55

  Carceles C M ^a   Font, A ^a   Espuny, A ^a   Fernández Varón, Emilia ^a   Serrano, J M ^b   Escudero, E ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN;

ADOLESCENT; AGAR GEL DIFFUSION; APPARENT VOLUME OF DISTRIBUTION AT STEADY STATE; ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; FEMALE; FIRST ORDER KINETICS; GOAT; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; SINGLE DRUG DOSE; STEADY STATE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; AZITHROMYCIN; CROSS-OVER STUDIES; GOATS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; MALE;

CAPRA HIRCUS;

EID: 14844356068     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2004.00626.x     Document Type: Article

References (23)

1. Ballow, C.H. & Amsden, G.W. (1992) Azithromycin: the first azalide antibiotic. The Annals of Pharmacotherapy, 26, 1253-1261.
2. Bright, G.M., Nagel, A.A., Bordner, J. et al. (1988) Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-aza-9a homoerythromycin A derivatives: a new class of macrolide antibiotics, the azalides. Journal of Antibiotics, 41, 1029-1047.
3. Davila, D. & Kolacny-Babic, L. (1991) Pharmacokinetics of azithromycin after single oral dosing of experimental animals. Biopharmaceutics and Drug Disposition, 12, 505-514.
4. Davis, J.L., Gardner, S.Y., Jones, S.L., Schwabenton, B.A. & Papich, M.G. (2002) Pharmacokinetics of azithromycin in foals after I.V. and oral dose and disposition into phagocytes. Joural of Veterinary Pharmacology and Therapeutics, 25, 99-104.
5. Fiese, E.F. & Steffen, S.H. (1990) Comparison of the acid stability of azithromycin and erythromycin A. Journal of Antimicrobial Chemotherapy, 25(Suppl. A), 39-47.
6. Foulds, G., Shepard, R.M. & Johnson, R.B. (1990) The pharmacokinetics of azithromycin in human serum and tissues. Journal of Antimicrobial Chemotherapy, 25(Suppl. A), 73-82.
7. Gibaldi, M. & Perrier, P. (1982) Pharmacokinetics, 2nd edn. Marcel Dekker, New York.
8. Girard, A.E., Girad, D., English, A.R., Goots, T.D., Comochowski, C.R., Faiella, J.A., Haskel, S.L. & Retsema J.A. (1987) Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with and extended half-life and excellent tissue distribution. Antomicrobial Agents and Chemotherapy, 31, 1948-1954.
9. Girard, A.E., Girard, D. & Retsema, J.A. (1990) Correlation of the extravascular pharmacokinetics of azithromycin with in vivo efficacy in models of localised infection. Journal of Antomicrobial Chemothrerapy, 25(Suppl. A), 61-71.
10. Hunter, R.P., Lynch, M.J., Ericson, J.F., Millas, W.J., Fletcher, A.M., Ryan, N.I. & Olson J.A. (1995) Pharmacokinetics, oral bioavailability and tissue distribution of azithromycin in cats. Journal of Veterinary Pharmacology and Therapeutics, 18, 38-46.
11. Jacks, S., Giguere, S., Gronwall, P.R., Brown, M.P. & Merritt, K.A. (2001) Pharmacokinetics of azithromycin and concentration in body fluids and broncoalveolar cells in foals. American Journal of Veterinary Research, 62, 1870-1875.
12. Lalak, N.J. & Morris, D.L. (1993) Azithromycin clinical pharmacokinetics. Clinical Pharmacokinetics, 25, 370-374.
13. Peters, D.H., Freidel, H.A. & McTavish, D. (1992) Azithromycin. A review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy. Drugs, 44, 750-799.
14. Prescott, J.F., Baggot J.D. & Walker, R.D. (2000) Antimicrobial Therapy, 3rd edn. Saunders, Philadelphia.
15. Rapp, R.P. (1998) Pharmacokinetics and pharmacodynamics of intravenous and oral azithromycin: enhance tissue activity and minimal drug interactions. Annals of Pharmacotherapy, 32, 785-793.
16. Retsema, J., Girard, A., Shelkley, W., Manousos, M., Anderson, M., Bright, G.M., Borovoy, R., Brennan, L. & Mason, R. (1987) Spectrum and mode of action of azithromycin (CP-62.993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrobial Agents and Chemotherapy, 31, 1939-1947.
17. Retsema, J.A., Girard, A.E., Girard, D. & Milisen, W.P. (1990) Relationship of high tissue concentrations of azithromycin to bactericidal activity and efficacy in vivo. Journal of Antimicrobial Chemotherapy, 25(Suppl. A), 83-89.
18. Riedel, K.D., Wildfever, A., Laufen, H. & Zimmermann, T. (1992) Equivalence of a high-performance liquid Chromatographic assay and a bioassay of azithromycin in human serum samples. Journal of Chromatography, 576, 358-362.
19. Ripa, S., Ferrante, L. & Prenna, M. (1996) A linear model for the pharmacokinetics of azithromycin in healthy volunteers. Chemotherapy, 42, 402-409.
20. Shepard, R.M. & Falkner, F.C. (1990) Pharmacokinetics of azithromycin in rats and dogs. Journal of Antimicrobial Chemotherapy, 25(Suppl. A), 49-60.
21. Shumaker, R.C. (1986) PKCALC: a basic interactive computer program for statistical and pharmacokinetic analysis of data. Drugs Metabolism Reviews, 17, 331-348.
22. Stamler, D.A., Edelstein, M.A.C. & Edelstein, P.H. (1994) Azithromycin Pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophages. Antimicrobial Agents and Chemotherapy, 38, 217-222.
23. Yamaoka, K., Nakagawa, T. & Uno, T. (1978) Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. Journal of Pharmacokinetics and Biopharmaceutics, 6, 165-175.