ICAM-1 contributes to but is not essential for tumor antigen cross-priming and CD8+ T cell-mediated tumor rejection in vivo

Journal of Immunology

Volumn 174, Issue 6, 2005, Pages 3416-3420

  Blank, Christian ^a,b   Brown, Ian ^a   Kacha, Aalok K ^a   Markiewicz, Mary A ^a   Gajewski, Thomas F ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD8 ANTIGEN; H2 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; KB ANTIGEN; LD ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; RAG2 PROTEIN; SERYLISOLEUCYLTYROSYLARGINYLGLYCYLLEUCINE; SYNTHETIC PEPTIDE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; CROSS PRESENTATION; EFFECTOR CELL; ENZYME LINKED IMMUNOSPOT ASSAY; IMMUNE RESPONSE; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; TUMOR CELL LINE; TUMOR GROWTH; TUMOR REJECTION;

EID: 14844344816     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.6.3416     Document Type: Article

References (26)

1. Van Seventer, G. A., Y. Shimizu, K. J. Horgan, and S. Shaw. 1990. The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells. J. Immunol. 144:4579.
2. Gaglia, J. L., E. A. Greenfield, A. Mattoo, A. H. Sharpe, G. J. Freeman, and V. K. Kuchroo. 2000. Intercellular adhesion molecule 1 is critical for activation of CD28-deficient T cells. J. Immunol. 165:6091.
3. + T cell proliferation requires phosphatidylinositol 3-kinase activity. J. Immunol. 166:6523.
4. Abraham, C., and J. Miller. 2001. Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1. J. Immunol. 167:5193.
5. Zuckerman, L. A., L. Pullen, and J. Miller. 1998. Functional consequences of costimulation by ICAM-1 on IL-2 gene expression and T cell activation. J. Immunol. 160:3259.
6. Smits, H. H., E. C. de Jong, J. H. Schuitemaker, T. B. Geijtenbeek, Y. van Kooyk, M. L. Kapsenberg, and E. A. Wierenga. 2002. Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development. J. Immunol. 168:1710.
7. + T cells are poorly costimulated by ICAM-1. Eur. J. Immunol. 29:45.
8. Chen, T., J. S. Goldstein, K. O'Boyle, M. C. Whitman, M. Brunswick, and S. Kozlowski. 1999. ICAM-1 co-stimulation has differential effects on the activation of CD4+ and CD8+ T cells. Eur. J. Immunol. 29:809.
9. + T cell activation and cytolytic function in the absence of LFA-1 cannot be restored by increased TCR signaling. J. Immunol. 163:4826.
10. Reiss, Y., and B. Engelhardt. 1999. T cell interaction with ICAM-1-deficient endothelium in vitro: transendothelial migration of different T cell populations is mediated by endothelial ICAM-1 and ICAM-2. Int. Immunol. 11:1527.
11. Reiss, Y., G. Hoch, U. Deutsch, and B. Engelhardt. 1998. T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells. Eur. J. Immunol. 28:3086.
12. Turner, J., J. G. Rhee, D. F. Fabian, and A. T. Lefor. 1997. Expression of ICAM-1 enhances in vivo lymphocyte adhesion in a murine fibrosarcoma. J. Surg. Oncol. 66:39.
13. Sartor, W. M., N. Kyprianou, D. F. Fabian, and A. T. Lefor. 1995. Enhanced expression of ICAM-1 in a murine fibrosarcoma reduces tumor growth rate. J. Surg. Res. 59:66.
14. Lefor, A. T., and D. F. Fabian. 1998. Enhanced cytolytic activity of tumor infiltrating lymphocytes (TILs) derived from an ICAM-1 transfected tumor in a murine model. J. Surg. Res. 75:49.
15. Schmits, R., T. M. Kundig, D. M. Baker, G. Shumaker, J. J. Simard, G. Duncan, A. Wakeham, A. Shahinian, A. van der Heiden, M. F. Bachmann, et al. 1996. LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J. Exp. Med. 183:1415.
16. Sha, W. C., C. A. Nelson, R. D. Newberry, D. M. Kranz, J. H. Russell, and D. Y. Loh. 1988. Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature 335:271.
17. Philpott, K. L., J. L. Viney, G. Kay, S. Rastan, E. M. Gardiner, S. Chae, A. C. Hayday, and M. J. Owen. 1992. Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells. Science 256:1448.
18. Sligh, J. E., Jr., C. M. Ballantyne, S. S. Rich, H. K. Hawkins, C. W. Smith, A. Bradley, and A. L. Beaudet. 1993. Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. USA 90:8529.
19. Kranz, D. M., S. Tonegawa, and H. N. Eisen. 1984. Attachment of an antireceptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA 81:7922.
20. Fallarino, F., C. Uyttenhove, T. Boon, and T. F. Gajewski. 1999. Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12. Int. J. Cancer 80:324.
21. + TCR-transgenic T cells. J. Immunol. 161:5268.
22. + T lymphocytes in the P815 tumor system in vitro. J. Immunol. 156:465.
23. Spiotto, M. T., P. Yu, D. A. Rowley, M. I. Nishimura, S. C. Meredith, T. F. Gajewski, Y. X. Fu, and H. Schreiber. 2002. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity 17:737.
24. Seliger, B., U. Wollscheid, F. Momburg, T. Blankenstein, and C. Huber. 2001. Characterization of the major histocompatibility complex class I deficiencies in B16 melanoma cells. Cancer Res. 61:1095.
25. Kikuchi, T., T. Joki, Y. Akasaki, Y., Abe, and T. Ohno. 1999. Induction of antitumor immunity using intercellular adhesion molecule 1 (ICAM-1) transfection in mouse glioma cells. Cancer Lett. 142:201.
26. Hallahan, D. E., and S. Virudachalam. 1997. Intercellular adhesion molecule 1 knockout abrogates radiation induced pulmonary inflammation. Proc. Natl. Acad. Sci. USA 94:6432.