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Volumn 142, Issue 6, 2005, Pages

Thyroid hormone replacement therapy in primary hypothyroidism: A randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DEOXYPYRIDINOLINE; LEVOTHYROXINE SODIUM; LIOTRIX; THYROTROPIN; LIOTHYRONINE; THYROXINE;

EID: 14844339782     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-142-6-200503150-00007     Document Type: Article
Times cited : (139)

References (40)
  • 1
    • 0003020857 scopus 로고
    • Hypothyroidism
    • De Groot LJ, ed. Philadelphia: WB Saunders
    • Utiger RD. Hypothyroidism. In: De Groot LJ, ed. Endocrinology. 3rd ed. Philadelphia: WB Saunders; 1995:752-68.
    • (1995) Endocrinology. 3rd Ed. , pp. 752-768
    • Utiger, R.D.1
  • 3
    • 14944340334 scopus 로고
    • Conversion of T4 to T3 and its relation to hormonal activity
    • Reinwein D, ed. Stuttgart: F.K. Schattaner Verlag
    • Morreale de Escobar G. Conversion of T4 to T3 and its relation to hormonal activity. In: Reinwein D, ed. Regulation of Thyroid Function, vol 1. Stuttgart: F.K. Schattaner Verlag; 1976:109-29.
    • (1976) Regulation of Thyroid Function , vol.1 , pp. 109-129
    • Morreale De Escobar, G.1
  • 4
    • 0028861989 scopus 로고
    • Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats
    • PMID: 8675653
    • Escobar-Morreale HF, Obregon MJ, Escobar del Rey F, Morreale de Escobar G. Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats. J Clin Invest. 1995;96:2828-38. [PMID: 8675653]
    • (1995) J Clin Invest , vol.96 , pp. 2828-2838
    • Escobar-Morreale, H.F.1    Obregon, M.J.2    Escobar Del Rey, F.3    Morreale De Escobar, G.4
  • 5
    • 0029938145 scopus 로고    scopus 로고
    • Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat
    • PMID: 8641203
    • Escobar-Morreale HF, Escobar del Rey F, Obregón MJ, de Escobar G Escobar. Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat. Endocrinology. 1996;137:2490-502. [PMID: 8641203]
    • (1996) Endocrinology , vol.137 , pp. 2490-2502
    • Escobar-Morreale, H.F.1    Escobar Del Rey, F.2    Obregón, M.J.3    De Escobar, G.4
  • 6
    • 0014953297 scopus 로고
    • Controlled clinical trial of combined triiodothyronine and thyroxine in the treatment of hypothyroidism
    • PMID: 4097650
    • Smith RN, Taylor SA, Massey JC. Controlled clinical trial of combined triiodothyronine and thyroxine in the treatment of hypothyroidism. Br Med J. 1970;4:145-8. [PMID: 4097650]
    • (1970) Br Med J , vol.4 , pp. 145-148
    • Smith, R.N.1    Taylor, S.A.2    Massey, J.C.3
  • 7
    • 18744419707 scopus 로고    scopus 로고
    • Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism
    • PMID: 9971866
    • Bunevicius R, Kazanavicius G, Zalinkevicius R, Prange AJ Jr. Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism. N Engl J Med. 1999;340:424-9. [PMID: 9971866]
    • (1999) N Engl J Med , vol.340 , pp. 424-429
    • Bunevicius, R.1    Kazanavicius, G.2    Zalinkevicius, R.3    Prange Jr., A.J.4
  • 8
    • 0033920253 scopus 로고    scopus 로고
    • Mental improvement after replacement therapy with thyroxine plus triiodothyronine: Relationship to cause of hypothyroidism
    • PMID: 11343593
    • Bunevicius R, Prange AJ. Mental improvement after replacement therapy with thyroxine plus triiodothyronine: relationship to cause of hypothyroidism. Int J Neuropsychopharmacol. 2000;3:167-174. [PMID: 11343593]
    • (2000) Int J Neuropsychopharmacol , vol.3 , pp. 167-174
    • Bunevicius, R.1    Prange, A.J.2
  • 9
    • 10744221589 scopus 로고    scopus 로고
    • Combined thyroxine/liothyronine treatment does not improve well-being, quality of life, or cognitive function compared to thyroxine alone: A randomized controlled trial in patients with primary hypothyroidism
    • PMID: 14557419
    • Walsh JP, Shiels L, Lim EM, Bhagat CI, Ward LC, Stuckey BG, et al. Combined thyroxine/liothyronine treatment does not improve well-being, quality of life, or cognitive function compared to thyroxine alone: a randomized controlled trial in patients with primary hypothyroidism. J Clin Endocrinol Metab. 2003;88:4543-50. [PMID: 14557419]
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4543-4550
    • Walsh, J.P.1    Shiels, L.2    Lim, E.M.3    Bhagat, C.I.4    Ward, L.C.5    Stuckey, B.G.6
  • 10
    • 0345060920 scopus 로고    scopus 로고
    • Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: A randomized controlled trial
    • PMID: 14665656
    • Clyde PW, Harari AE, Getka EJ, Shakir KM. Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: a randomized controlled trial. JAMA. 2003;290:2952-8. [PMID: 14665656]
    • (2003) JAMA , vol.290 , pp. 2952-2958
    • Clyde, P.W.1    Harari, A.E.2    Getka, E.J.3    Shakir, K.M.4
  • 11
    • 0242288746 scopus 로고    scopus 로고
    • Does a combination regimen of thyroxine (T4) and 3,5,3′- triiodothyronine improve depressive symptoms better than T4 alone in patients with hypothyroidism? Results of a double-blind, randomized, controlled trial
    • PMID: 14557420
    • Sawka AM, Gerstein HC, Marriott MJ, MacQueen GM, Joffe RT. Does a combination regimen of thyroxine (T4) and 3,5,3′-triiodothyronine improve depressive symptoms better than T4 alone in patients with hypothyroidism? Results of a double-blind, randomized, controlled trial. J Clin Endocrinol Metab. 2003; 88:4551-5. [PMID: 14557420]
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4551-4555
    • Sawka, A.M.1    Gerstein, H.C.2    Marriott, M.J.3    MacQueen, G.M.4    Joffe, R.T.5
  • 12
    • 0242288751 scopus 로고    scopus 로고
    • In search of the impossible dream? Thyroid hormone replacement therapy that treats all symptoms in all hypothyroid patients
    • PMID: 14557418
    • Kaplan MM, Sarne DH, Schneider AB. In search of the impossible dream? Thyroid hormone replacement therapy that treats all symptoms in all hypothyroid patients [Editorial]. J Clin Endocrinol Metab. 2003;88:4540-2. [PMID: 14557418]
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4540-4542
    • Kaplan, M.M.1    Sarne, D.H.2    Schneider, A.B.3
  • 13
    • 0033545344 scopus 로고    scopus 로고
    • Thyroid hormone replacement-one hormone or two?
    • PMID: 9971874
    • Toft AD. Thyroid hormone replacement-one hormone or two? [Editorial]. N Engl J Med. 1999;340:469-70. [PMID: 9971874]
    • (1999) N Engl J Med , vol.340 , pp. 469-470
    • Toft, A.D.1
  • 14
    • 0025366287 scopus 로고
    • Thyroidal and peripheral production of 3,5,3′-triiodothyronine in humans by multicompartmental analysis
    • PMID: 2333963
    • Pilo A, Iervasi G, Vitek F, Ferdeghini M, Cazzuola F, Bianchi R. Thyroidal and peripheral production of 3,5,3′-triiodothyronine in humans by multicompartmental analysis. Am J Physiol. 1990;258:E715-26. [PMID: 2333963]
    • (1990) Am J Physiol , vol.258
    • Pilo, A.1    Iervasi, G.2    Vitek, F.3    Ferdeghini, M.4    Cazzuola, F.5    Bianchi, R.6
  • 15
    • 3042598173 scopus 로고    scopus 로고
    • Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma
    • PMID: 15163309
    • Botella-Carretero JI, Gomez-Bueno M, Barrios V, Caballero C, Garcia-Robles R, Sancho J, et al. Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma. Endocr Relat Cancer. 2004;11:345-56. [PMID: 15163309]
    • (2004) Endocr Relat Cancer , vol.11 , pp. 345-356
    • Botella-Carretero, J.I.1    Gomez-Bueno, M.2    Barrios, V.3    Caballero, C.4    Garcia-Robles, R.5    Sancho, J.6
  • 16
    • 0031057078 scopus 로고    scopus 로고
    • Estimation of tissue hypothyroidism by a new clinical score: Evaluation of patients with various grades of hypothyroidism and controls
    • PMID: 9062480
    • Zulewski H, Muller B, Exer P, Miserez AR, Staub JJ. Estimation of tissue hypothyroidism by a new clinical score: evaluation of patients with various grades of hypothyroidism and controls. J Clin Endocrinol Metab. 1997;82:771-6. [PMID: 9062480]
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 771-776
    • Zulewski, H.1    Muller, B.2    Exer, P.3    Miserez, A.R.4    Staub, J.J.5
  • 18
    • 0025287962 scopus 로고
    • Spanish version of the Nottingham Health Profile: Translation and preliminary validity
    • PMID: 2343954
    • Alonso J, Anto JM, Moreno C. Spanish version of the Nottingham Health Profile: translation and preliminary validity. Am J Public Health. 1990;80:704-8. [PMID: 2343954]
    • (1990) Am J Public Health , vol.80 , pp. 704-708
    • Alonso, J.1    Anto, J.M.2    Moreno, C.3
  • 19
    • 0028566721 scopus 로고
    • The Spanish version of the Nottingham Health Profile: A review of adaptation and instrument characteristics
    • PMID: 7866356
    • Alonso J, Prieto L, Anto JM. The Spanish version of the Nottingham Health Profile: a review of adaptation and instrument characteristics. Qual Life Res. 1994;3:385-93. [PMID: 7866356]
    • (1994) Qual Life Res , vol.3 , pp. 385-393
    • Alonso, J.1    Prieto, L.2    Anto, J.M.3
  • 20
    • 0032505341 scopus 로고    scopus 로고
    • Population reference values of the Spanish version of the Health Questionnaire SF-36
    • PMID: 9834913
    • Alonso J, Regidor E, Barrio G, Prieto L, Rodriguez C, de la Fuente L. [Population reference values of the Spanish version of the Health Questionnaire SF-36]. Med Clin (Barc). 1998;111:410-6. [PMID: 9834913]
    • (1998) Med Clin (Barc) , vol.111 , pp. 410-416
    • Alonso, J.1    Regidor, E.2    Barrio, G.3    Prieto, L.4    Rodriguez, C.5    De La Fuente, L.6
  • 21
    • 0032211585 scopus 로고    scopus 로고
    • Translating health status questionnaires and evaluating their quality: The IQOLA Project approach. International Quality of Life Assessment
    • PMID: 9817108
    • Bullinger M, Alonso J, Apolone G, Leplege A, Sullivan M, Wood-Dauphinee S, et al. Translating health status questionnaires and evaluating their quality: the IQOLA Project approach. International Quality of Life Assessment. J Clin Epidemiol. 1998;51:913-23. [PMID: 9817108]
    • (1998) J Clin Epidemiol , vol.51 , pp. 913-923
    • Bullinger, M.1    Alonso, J.2    Apolone, G.3    Leplege, A.4    Sullivan, M.5    Wood-Dauphinee, S.6
  • 22
    • 0027168511 scopus 로고
    • The SF36 health survey questionnaire: An outcome measure suitable for routine use within the NHS?
    • PMID: 8518640
    • Garratt AM, Ruta DA, Abdalla MI, Buckingham JK, Russell IT. The SF36 health survey questionnaire: an outcome measure suitable for routine use within the NHS? BMJ. 1993;306:1440-4. [PMID: 8518640]
    • (1993) BMJ , vol.306 , pp. 1440-1444
    • Garratt, A.M.1    Ruta, D.A.2    Abdalla, M.I.3    Buckingham, J.K.4    Russell, I.T.5
  • 25
    • 0002942461 scopus 로고
    • Mental state assessment of young and elderly adults in behavioral neurology
    • Mesulam MM, ed. Philadelphia: FA Davis
    • Weintraub S, Mesulam M. Mental state assessment of young and elderly adults in behavioral neurology. In: Mesulam MM, ed. Principles of Behavioral Neurology. Philadelphia: FA Davis; 1985:71-122.
    • (1985) Principles of Behavioral Neurology , pp. 71-122
    • Weintraub, S.1    Mesulam, M.2
  • 28
    • 0032607560 scopus 로고    scopus 로고
    • Recommended standards for pattern electroretinograms and visual evoked potentials
    • The International Federation of Clinical Neurophysiology. PMID: 10590976
    • Celesia GG, Brigell MG. Recommended standards for pattern electroretinograms and visual evoked potentials. The International Federation of Clinical Neurophysiology. Electroencephalogr Clin Neurophysiol Suppl. 1999;52:53-67. [PMID: 10590976]
    • (1999) Electroencephalogr Clin Neurophysiol Suppl , vol.52 , pp. 53-67
    • Celesia, G.G.1    Brigell, M.G.2
  • 29
    • 0032614553 scopus 로고    scopus 로고
    • Short-latency auditory evoked potentials
    • The International Federation of Clinical Neurophysiology. PMID: 10590977
    • Pratt H, Aminoff M, Nuwer MR, Starr A. Short-latency auditory evoked potentials. The International Federation of Clinical Neurophysiology. Electroencephalogr Clin Neurophysiol Suppl. 1999;52:69-77. [PMID: 10590977]
    • (1999) Electroencephalogr Clin Neurophysiol Suppl , vol.52 , pp. 69-77
    • Pratt, H.1    Aminoff, M.2    Nuwer, M.R.3    Starr, A.4
  • 30
    • 0028691960 scopus 로고
    • Review of nonparametric methods for the analysis of crossover studies
    • PMID: 7889227
    • Tudor G, Koch GG. Review of nonparametric methods for the analysis of crossover studies. Stat Methods Med Res. 1994;3:345-81. [PMID: 7889227]
    • (1994) Stat Methods Med Res , vol.3 , pp. 345-381
    • Tudor, G.1    Koch, G.G.2
  • 32
    • 0032729203 scopus 로고    scopus 로고
    • Tissue-specific patterns of changes in 3,5,3′-triiodo-L-thyronine concentrations in thyroidectomized rats infused with increasing doses of the hormone. Which are the regulatory mechanisms?
    • PMID: 10403175
    • Escobar-Morreale HF, Obregón MJ, Escobar del Rey F, Morreale de Escobar G. Tissue-specific patterns of changes in 3,5,3′-triiodo-L- thyronine concentrations in thyroidectomized rats infused with increasing doses of the hormone. Which are the regulatory mechanisms? Biochimie. 1999;81:453-62. [PMID: 10403175]
    • (1999) Biochimie , vol.81 , pp. 453-462
    • Escobar-Morreale, H.F.1    Obregón, M.J.2    Escobar Del Rey, F.3    Morreale De Escobar, G.4
  • 33
    • 2942716790 scopus 로고    scopus 로고
    • Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14:1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism
    • PMID: 15163340
    • Siegmund W, Spieker K, Weike AI, Giessmann T, Modess C, Dabers T, et al. Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14:1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism. Clin Endocrinol (Oxf). 2004;60:750-7. [PMID: 15163340]
    • (2004) Clin Endocrinol (Oxf) , vol.60 , pp. 750-757
    • Siegmund, W.1    Spieker, K.2    Weike, A.I.3    Giessmann, T.4    Modess, C.5    Dabers, T.6
  • 34
    • 0036426814 scopus 로고    scopus 로고
    • Psychological well-being in patients on 'adequate' doses of 1-thyroxine: Results of a large, controlled community-based questionnaire study
    • PMID: 12390330
    • Saravanan P, Chau WF, Roberts N, Vedhara K, Greenwood R, Dayan CM. Psychological well-being in patients on 'adequate' doses of 1-thyroxine: results of a large, controlled community-based questionnaire study. Clin Endocrinol (Oxf). 2002;57:577-85. [PMID: 12390330]
    • (2002) Clin Endocrinol (Oxf) , vol.57 , pp. 577-585
    • Saravanan, P.1    Chau, W.F.2    Roberts, N.3    Vedhara, K.4    Greenwood, R.5    Dayan, C.M.6
  • 35
    • 0036428317 scopus 로고    scopus 로고
    • Psychological wellbeing in patients
    • PMID: 12390329
    • Ladenson PW. Psychological wellbeing in patients. Clin Endocrinol (Oxf). 2002;57:575-6. [PMID: 12390329]
    • (2002) Clin Endocrinol (Oxf) , vol.57 , pp. 575-576
    • Ladenson, P.W.1
  • 36
    • 0345600946 scopus 로고    scopus 로고
    • Combined T4 and T3 therapy-back to the drawing board
    • PMID: 14665664
    • Cooper DS. Combined T4 and T3 therapy-back to the drawing board [Editorial]. JAMA. 2003;290:3002-4. [PMID: 14665664]
    • (2003) JAMA , vol.290 , pp. 3002-3004
    • Cooper, D.S.1
  • 37
    • 0023103073 scopus 로고
    • Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans
    • PMID: 3821822
    • Fish LH, Schwartz HL, Cavanaugh J, Steffes MW, Bantle JP, Oppenheimer JH. Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans. N Engl J Med. 1987;316:764-70. [PMID: 3821822]
    • (1987) N Engl J Med , vol.316 , pp. 764-770
    • Fish, L.H.1    Schwartz, H.L.2    Cavanaugh, J.3    Steffes, M.W.4    Bantle, J.P.5    Oppenheimer, J.H.6
  • 38
    • 0019960694 scopus 로고
    • Bioavailabiliry of thyroid hormones from oral replacement preparations
    • PMID: 7121261
    • LeBoff MS, Kaplan MM, Silva JE, Larsen PR. Bioavailabiliry of thyroid hormones from oral replacement preparations. Metabolism. 1982;31:900-5. [PMID: 7121261]
    • (1982) Metabolism , vol.31 , pp. 900-905
    • LeBoff, M.S.1    Kaplan, M.M.2    Silva, J.E.3    Larsen, P.R.4
  • 39
    • 2342519483 scopus 로고    scopus 로고
    • Thyroxine plus low-dose, slow-release triiodothyronine replacement in hypothyroidism: Proof of principle
    • PMID: 15142360
    • Hennemann G, Docter R, Visser TJ, Postema PT, Krenning EP. Thyroxine plus low-dose, slow-release triiodothyronine replacement in hypothyroidism: proof of principle. Thyroid. 2004;14:271-5. [PMID: 15142360]
    • (2004) Thyroid , vol.14 , pp. 271-275
    • Hennemann, G.1    Docter, R.2    Visser, T.J.3    Postema, P.T.4    Krenning, E.P.5
  • 40
    • 0036658669 scopus 로고    scopus 로고
    • Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for Graves' disease
    • PMID: 12374459
    • Bunevicius R, Jakubonien N, Jurkevicius R, Cernicat J, Lasas L, Prange AJ Jr. Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for Graves' disease. Endocrine. 2002;18:129-33. [PMID: 12374459]
    • (2002) Endocrine , vol.18 , pp. 129-133
    • Bunevicius, R.1    Jakubonien, N.2    Jurkevicius, R.3    Cernicat, J.4    Lasas, L.5    Prange Jr., A.J.6


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