Scyllo-inositol in normal aging human brain: 1H magnetic resonance spectroscopy study at 4 Tesla

NMR in Biomedicine

Volumn 18, Issue 1, 2005, Pages 51-55

  Kaiser, Lana G ^a   Schuff, Norbert ^a   Cashdollar, Nathan ^a   Weiner, Michael W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

4T; Aging; Human brain; Myo inositol; Scyllo inositol; Spectroscopy; Taurine; White matter

Indexed keywords

BIOMEDICAL ENGINEERING; MAGNETIC RESONANCE SPECTROSCOPY; METABOLITES;

CORONA RADIATA; METABOLITE SPECTRA; MYO-INOSITOL; SCYLLO-INOSITOL;

BRAIN;

CHOLINE; GLUTAMIC ACID; GLUTAMINE; INOSITOL; INOSITOL DERIVATIVE; N ACETYLASPARTIC ACID; SCYLLOINOSITOL; TAU PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; CEREBROSPINAL FLUID; COMPUTER SIMULATION; CONSTANTS AND COEFFICIENTS; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; HUMAN EXPERIMENT; IMAGE ANALYSIS; IN VIVO STUDY; MALE; MEASUREMENT; METABOLITE; NEUROIMAGING; NORMAL HUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REGRESSION ANALYSIS; WHITE MATTER;

ADAPTATION, PHYSIOLOGICAL; ADULT; AGED; AGING; BRAIN; FEMALE; HUMANS; INOSITOL; INTERNAL CAPSULE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED; PROTONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STATISTICS; TISSUE DISTRIBUTION;

ILEX COOKII;

EID: 14844322307     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/nbm.927     Document Type: Article

References (26)

1. 13C NMR. Magn. Reson. Med. 1998; 39: 313-316.
2. Lien Y-HH, Michaelis T, Moats RA, Ross BD. Scyllo inositol depletion in hepatic encephalopathy. Life Sci. 1994; 54: 1507-1512.
3. Meyerhoff DJ, Fein G, Weiner MW. Elevated scyllo inositol in adult human brain. In Proceedings of ISMRM, 4th Scientific Meeting, New York, 1996; 954.
4. Michaelis T, Helms G, Merboldt K-D, Hanicke W, Bruhn H, Frahm J. Identification of scyllo-inositol in proton NMR spectra of human brain in vivo. NMR Biomed. 1993; 6: 105-109.
5. Frahm J, Bruhn H, Hanicke W, Merboldt KD, Mursch K, Markakis E. Localized proton NMR spectroscopy of brain tumors using short-echo time STEAM sequences. J. Comput. Assist. Tomogr. 1991; 15: 915-919.
6. 1H NMR spectroscopy of the human brain at 7 T. Magn. Reson. Med. 2001; 46: 451-456.
7. Hoult DI, Lauterbur PC. The sensitivity of the zeumatographic experiment involving human samples. J. Magn. Reson. 1979; 34: 425-433.
8. Vadnal R, Parthasarathy L, Parthasarathy R. Promising effects of the natural sugar: myo-inositol. Nutr. Neurosci. 1998; 1: 21-33.
9. Garcia-Perez A, Burg MB. Renal medullary organic osmolytes. Physiol. Rev. 1991; 71: 1081-1115.
10. Downes CP. Macphee CH. Myo-inositol metabolites as cellular signals. Eur. J. Biochem. 1990; 193: 1-18.
11. 1H MR spectroscopy study at 4 Tesla. Neurobiol. Aging 2004 (in press).
12. Seeger U, Klose U, Mader I, Grodd W, Nagele T. Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases. Magn. Reson. Med. 2003; 49: 19-28.
13. Groenen PM, Merkus HM, Sweep FC, Wevers RA, Janssen FS, Steegers-Theunissen RP. Kinetics of myo-inositol loading in women of reproductive age. Ann. Clin. Biochem. 2003; 40: 79-85.
14. Frahm J, Merboldt K-D, Hänicke W. Localized proton spectroscopy using stimulated echoes. J. Magn. Reson. 1987; 72 502-508.
15. Matson GB. An integrated program for amplitude-modulated RF pulse generation and re-mapping with shaped gradients. Magn. Reson. Imag. 1994; 12: 1205-1225.
16. 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn. Reson. Med. 1999; 41: 649-656.
17. 1H-MRS using water as an internal standard. Magn. Reson. Imag. 1993; 11: 107-118.
18. Seeger U, Klose U, Seitz D, Nagele T, Lutz O, Grodd W. Proton spectroscopy of human brain with very short echo time using high gradient amplitudes. Magn. Reson. Imag. 1998; 16: 55-62.
19. Young K, Govindaraju V, Soher BJ, Maudsley AA. Automated spectral analysis I: formation of a priori information by spectral simulation. Magn. Reson. Med. 1998; 40: 812-815.
20. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed. 2000; 13: 129-153.
21. Smith SA, Levante TO, Meier BH, Ernst RR. Computer simulations in magnetic resonance. An object oriented programming approach. J. Magn. Reson. A 1994; 106: 75-105.
22. Sherman W, Stewart M, Kurien M, Goodwin S. The measurement of myo-inositol, myo-inosose-2 and scyllo-inositol in mammalian tissues. Biochim. Biophys. Acta 1968; 158: 197-205.
23. Fisher SK, Novak JE, Agranoff BW. Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance. J. Neurochem. 2002; 82: 736-754.
24. Chang L, Ernst T, Poland RE, Jenden DJ. In vivo proton magnetic resonance spectroscopy of the normal aging human brain. Life Sci. 1996; 58: 2049-2056.
25. Firbank MJ, Harrison RM, O'Brien JT. A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease. Dement. Geriatr. Cogn. Disord. 2002; 14: 64-76.
26. 1H spectroscopy at 1.5 and 4.0 Tesla. Magn. Reson. Med. 2000; 44: 185-192.