Expression of inducible nitric oxide synthase is increased in rat Barrett's esophagus induced by duodenal contents reflux

Journal of Korean Medical Science

Volumn 20, Issue 1, 2005, Pages 56-60

  Jong, Dae Bae ^a   Ki, Hoon Jung ^a   Woo, Sup Ahn ^a   Sung, Han Bae ^a   Tae, Jung Jang ^a  

^a Dongguk University   (South Korea)

Author keywords

Barrett Esophagus; Inducible nitric oxide synthase

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA;

ANASTOMOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARRETT ESOPHAGUS; CONTROLLED STUDY; CYTOPLASM; DUODENUM; EPITHELIUM CELL; ESOPHAGUS; GASTROINTESTINAL REFLUX; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING;

EID: 14844317316     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2005.20.1.56     Document Type: Article

References (29)

1. Schmidt HH, Walter U. NO at work. Cell 1994; 78: 919-25.
2. Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994; 298: 249-58.
3. Lala PK, Orucevic A. Role of nitric oxide in tumor progression: Lessons from experimental tumors. Cancer Metastasis Rev 1998; 17: 91-106.
4. Nathan C, Xie Q. Regulation of biosynthesis of nitric oxide. J Biol Chem 1994; 269: 13725-8.
5. Wink DA, Vodovotz Y, Laval J, Laval F, Dewhirst MW, Mitchell JB. The multifaceted roles of nitric oxide in cancer. Carcinogenesis 1998; 19: 711-21.
6. Felley-Bosco E. Role of nitric oxide in genotoxicity: implication for carcinogenesis. Cancer Metastasis Rev 1998; 17: 25-37.
7. Rachmilewitz D, Karmeli F, Eliakim R, Stalnikowicz R, Ackerman Z, Amir G, Stamler JS. Enhanced gastric nitric oxide synthase activity in duodenal ulcer patients. Gut 1994; 35: 1394-7.
8. Singer II, Kawaka DW, Scott S Weidner JR, Mumford RA, Riehl TE, Stenson WF. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 1996; 111: 871-85.
9. Haswell-Elkins MR, Satarug S, Tsuda M, Mairiang E, Esumi H, Sithithaworn P, Mairiang P, Saitoh M, Yongvanit P, Elkins DB. Liver fluke infection and cholangiocarcinoma: model of endogenous nitric oxide and extragastric nitrosation in human carcinogenesis. Mutat Res 1994; 305: 241-52.
10. Wilson KT, Fu S, Ramanujam KS, Meltzer SJ. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res 1998; 58: 2929-34.
11. Takahashi M, Fukuda K, Ohata T, Sugimura T, Wakabayashi K. Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane. Cancer Res 1997; 57: 1233-7.
12. Goldstein SR, Yang GY, Chen X, Curtis SK, Yang CS. Studies of iron deposits, inducible nitric oxide synthase and nitrotyrosine in a rat model for esophageal adenocarcinoma. Carcinogenesis 1998; 19: 1445-9.
13. Kauer WK, Peters JH, DeMeester TR, Ireland AP, Bremner CG, Hagen JA. Mixed reflux of gastric and duodenal juices is more harmful to the esophagus and gastric juice alone. Ann Surg 1995; 222: 525-33.
14. Gillen P, Keeling P, Byrne PJ, Healy M, O'Moore RR, Hennessy TP. Implication of duodenogastric reflux in the pathogenesis of Barrett's esophagus. Br J Surg 1988; 75: 540-3.
15. Goldstein SR, Yang GY, Curtis SK, Reuhl KR, Liu BC, Mirvish SS, Newmark HL, Yang CS. Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen. Carcinogenesis 1997; 18: 2265-70.
16. Miwa K, Sahara H, Segawa M, Kinami S, Sato T, Miyazaki I, Hattori T. Reflux of duodenal or gastro-duodenal contents induces esophageal carcinoma in rats. Int J Cancer 1996; 67: 269-74.
17. Fera M, Brito MJ, Poulsom R, Riera E, Grande L, Hanby A, Wright NA. Duodenal-content reflux esophagitis induces the development of glandular metaplasia and adenosquamous carcinoma in rats. Carcinogenesis 2000; 21: 1587-91.
18. Jang TJ, Min SK, Bae JD, Jung KH, Lee JI, Kim JR, Ahn WS. Expression of cyclooxygenase-2, microsomal prostaglandin E synthase-1 and EP receptors is increased in rat esophageal squamous cell dysplasia and Barrett's metaplasia induced by duodenal contents reflux. Gut 2004; 53: 27-33.
19. Di Rosa M, Ialenti A, Ianaro A, Sautebin L. Interaction between nitric oxide and cyclooxygenase (COX) pathways. Prostaglandins Leukot Essent Fatty Acids 1996; 54: 229-38.
20. Clark GW, Smyrk TC, Mirvish SS, Anselmino M, Yamashita Y, Hinder RA, DeMeester TR, Birt DF. Effect of gastroduodenal juice and dietary fat on the development of Barrett's esophagus and esophageal neoplasia: an experimental rat model. Ann Surg Oncol 1994; 1: 252-61.
21. Chen X, Yang CS. Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention. Carcinogenesis 2001; 22: 1119-29.
22. Chhatwal VJ, Nagoi SS, Chan ST, Chia YW, Moochhala SM. Aberrant expression of nitric oxide synthase in human polyps, neoplastic colonie mucosa and surrounding peritumoral normal mucosa. Carcinogenesis 1994; 15: 2081-5.
23. Moochhala S, Chhatwal VJ, Chan ST, Ngoi SS, Chia YW, Rauff A. Nitric oxide synthase activity and expression in human colorectal cancer. Carcinogenesis 1996; 17: 1171-4.
24. Scott DJ, Hull MA, Cartwright EJ, Lam WK, Tisbury A, Poulsom R, Markham AF, Bonifer C, Coletta PL. Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the ApcMin/+ mouse. Gastroenterology 2001; 121: 889-99.
25. Ahn B, Ohshima H. Suppression of intestinal polyposis in ApcMin/+ mice by inhibiting nitric oxide production. Cancer Res 2001; 61: 8357-60.
26. Timoshenko AV, Lala PK, Chakraborty C. PGE2 mediated upregulation of iNOS in murine breast cancer cells through the activation of EP4 receptors. Int J Cancer 2004; 108: 384-9.
27. Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P. Mine oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci USA 1993; 90: 7240-4.
28. Salvemini D, Seibert K, Masferrer JL, Misko TP, Currie MG, Needleman P. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Invest 1994; 93: 1940-7.
29. Buttar NS, Wang KK, Leontovich O, Westcott JY, Pacifico RJ, Anderson MA, Krishnadath KK, Lutzke LS, Burgart LJ. Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus. Gastroenterology 2002; 122: 1101-12.