Mammaglobin a in breast cancer: Existence of multiple molecular forms

International Journal of Cancer

Volumn 114, Issue 4, 2005, Pages 623-627

  O'Brien, Neil A ^a,b,c   O'Donovan, Norma ^a   Ryan, Bríd ^a,b,c   Hill, Arnold D K ^b,c   McDermott, Enda ^b,c   O'Higgins, Niall ^b,c   Duffy, Michael J ^a,b,c  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c Dublin Molecular Medicine Centre   (Ireland)

Author keywords

Breast cancer; Breast specific; Lipophilin; Mammaglobin; Tumor marker

Indexed keywords

HORMONE RECEPTOR; MAMMAGLOBIN; TUMOR MARKER;

ARTICLE; BREAST CANCER; BREAST FIBROADENOMA; CANCER GRADING; CELL PROLIFERATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE; METASTASIS; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; TUMOR GROWTH; TUMOR VOLUME; WESTERN BLOTTING;

BLOTTING, WESTERN; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROADENOMA; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPHATIC METASTASIS; MACROMOLECULAR SUBSTANCES; MYELIN PROTEINS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; PROGNOSIS; PROTEOLIPIDS; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL; UTEROGLOBIN;

EID: 14844312052     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20780     Document Type: Article

References (18)

1. Duffy MJ. Clinical uses of tumor markers: a critical review. Crit Rev Clin Lab Sci 2001;38:225-62.
2. Watson MA, Fleming TP. Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer Res 1996;56:860-5.
3. Becker RM, Darrow C, Zimonjic DB, Popescu NC, Watson MA, Fleming TP. Identification of mammaglobin B, a novel member of the uteroglobin gene family. Genomics 1998;54:70-8.
4. Colpitts TL, Billing-Medel P, Friedman P, Granados EN, Hayden M, Hodges S, Menhart N, Roberts L, Russell J, Stroupe SD. Mammaglobin is found in breast tissue as a complex with BU101. Biochemistry 2001;40:11048-59.
5. Jiang Y, Harlocker SL, Molesh DA, Dillon DC, Stolk JA, Houghton RL, Repasky EA, Badaro R, Reed SG, Xu J. Discovery of differentially expressed genes in human breast cancer using subtracted cDNA libraries and cDNA microarrays. Oncogene 2002;21:2270-82.
6. Houghton RL, Dillon DC, Molesh DA, Zehentner BK, Xu J, Jiang J, Schmidt C, Frudakis A, Repasky E, Maltez Filho A, Nolasco M, Badaro R, et al. Transcriptional complementarity in breast cancer: application to detection of circulating tumor cells. Mol Diagn 2001; 6:79-91.
7. Miksicek RJ, Myal Y, Watson PH, Walker C, Murphy LC, Leygue E. Identification of a novel breast- and salivary gland-specific, mucin-like gene strongly expressed in normal and tumor human mammary epithelium. Cancer Res 2002;62:2736-40.
8. Carter D, Douglass JF, Cornellison CD, Retter MW, Johnson JC, Bennington AA, Fleming TP, Reed SG, Houghton RL, Diamond DL, Vedvick TS. Purification and characterization of the mammaglobin/ lipophilin B complex, a promising diagnostic marker for breast cancer. Biochemistry 2002;41:6714-22.
9. Watson MA, Darrow C, Zimonjic DB, Popescu NC, Fleming TP. Structure and transcriptional regulation of the human mammaglobin gene, a breast cancer associated member of the uteroglobin gene family localized to chromosome 11q13. Oncogene 1998;16:817-24.
10. O'Brien N, Maguire TM, O'Donovan N, Lynch N, Hill AD, McDermott E, O'Higgins N, Duffy MJ. Mammaglobin a: a promising marker for breast cancer. Clin Chem 2002;48:1362-4.
11. Watson MA, Dintzis S, Darrow CM, Voss LE, DiPersio J, Jensen R, Fleming TP. Mammaglobin expression in primary, metastatic, and occult breast cancer. Cancer Res 1999;59:3028-31.
12. Fanger GR, Houghton RL, Retter MW, Hendrickson RC, Babcook J, Dillon DC, Durham MD, Reynolds LD, Johnson JC, Carter D, Fleming TP, Roche PC, et al. Detection of mammaglobin in the sera of patients with breast cancer. Tumor Biol 2002;23:212-21.
13. Han JH, Kang Y, Shin HC, Kim HS, Kang YM, Kim YB, Oh SY. Mammaglobin expression in lymph nodes is an important marker of metastatic breast carcinoma. Arch Pathol Lab Med 2003;127:1330-4.
14. Span PN, Waanders E, Manders P, Heuvel JM, Foekens JA, Watson MA, Beex LM, Sweep FJ. Mammaglobin is associated with low grade, steroid receptor-positive breast tumours from postmenopausal patients, and has independent prognostic value for relapse-free survival time. J Clin Oncol 2004;22:691-698.
15. Chen G, Gharib TG, Huang CC, Taylor JM, Misek DE, Kardia SL, Giordano TJ, Iannettoni MD, Orringer MB, Hanash SM, Beer DG. Discordant protein and mRNA expression in lung adenocarcinomas. Mol Cell Proteomics 2002;1:304-13.
16. Guan XF, Hamedani MK, Adeyinka A, Walker C, Kemp A, Murphy LC, Watson PH, Leygue E. Relationship between mammaglobin expression and estrogen receptor status in breast tumors. Endocrine 2003;21:245-50.
17. Marchetti A, Buttitta F, Bertacca G, Zavaglia K, Bevilacqua G, Angelucci D, Viacava P, Naccarato A, Bonadio A, Barassi F, Felicioni L, Salvatore S, et al. mRNA markers of breast cancer nodal metastases: comparison between mammaglobin and carcinoembryonic antigen in 248 patients. J Pathol 2001;195:186-90.
18. Zehentner BK, Dillon DC, Jiang Y, Xu J, Bennington A, Molesh DA, Zhang X, Reed SG, Persing D, Houghton RL. Application of a multigene reverse transcription-PCR assay for detection of mammaglobin and complementary transcribed genes in breast cancer lymph nodes. Clin Chem 2002;48:1225-31.