Liquid chromatography/tandem mass spectrometry for pharmacokinetic studies of 20(R)-ginsenoside Rg3 in dog

Rapid Communications in Mass Spectrometry

Volumn 19, Issue 6, 2005, Pages 813-817

  Li, Ke ^a   Chen, Xiaoyan ^a   Xu, Jinghua ^a   Li, Xin ^b   Zhong, Dafang ^a,b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RHODIUM COMPOUNDS;

DIOSCIN; ELECTROSPRAY IONIZATION INTERFACE; GINSENOSIDES; INTERNAL STANDARDS; LC-MS-MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; LIQUID-LIQUID EXTRACTION; PHARMACOKINETIC STUDIES; PLASMA SAMPLES;

PHARMACOKINETICS;

DRUG METABOLITE; GINSENOSIDE; GINSENOSIDE RG 2; GINSENOSIDE RG 3; PROTOPANAXADIOL; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STRUCTURE; FEMALE; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MEAN RESIDENCE TIME; NONHUMAN; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 14844307098     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1862     Document Type: Article

References (7)

1. Mochizuki M, Yoo YC, Matsuzawa K, Saiki I, Tonooka S, Samukawa KI, Azuma I. Bio. Pharm. Bull 1995; 18: 1197.
2. Shinkai K, Akedo H, Mukai M, Imamure F, Isoai A, Kobayashi M, Kitagawa I, Jpn. J. Cancer Res. 1996; 87: 357.
3. Wang H, Zou H, Kong L, Zhang Y, Pang H, Su C, Liu G, Hui M, Fu L. J. Chromatogr. B 1999; 731: 403.
4. Cai Z, Qian T, Wong RNS, Jiang ZH. Anal. Chim. Acta 2003; 492: 283.
5. Wang Y, Liu TH, Wang W, Wang BX. Acta Pharm. Sinica 2000; 35: 284.
6. Ma JS, Zhou JL, Fei XF, Sun Y, Wang BX. Acta Pharm. Sinica 2001; 36: 603.
7. Bae EA, Han MJ, Choo MK, Park SY, Kim DH. Biol. Pharm. Bull. 2002; 25: 58.