Endostatin induces acute endothelial nitric oxide and prostacyclin release

Biochemical and Biophysical Research Communications

Volumn 329, Issue 3, 2005, Pages 873-878

  Li, Chunying ^a   Harris, M Brennan ^a   Venema, Virginia J ^a   Venema, Richard C ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Endostatin; eNOS; Nitric oxide release; Phosphorylation

Indexed keywords

CYCLIC GMP; ENDOSTATIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROSTACYCLIN; SERINE; THREONINE; VASCULOTROPIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BLOOD VESSEL REACTIVITY; CELL ASSAY; CONTROLLED STUDY; COW; DEPHOSPHORYLATION; DRUG EFFECT; DRUG EXPOSURE; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; ENZYME PHOSPHORYLATION; EX VIVO STUDY; IMMUNOBLOTTING; LONG TERM EXPOSURE; MEDIATOR RELEASE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; RAT; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION;

EID: 14844301656     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.02.055     Document Type: Article

References (40)

1. M.S. O'Reilly, T. Boehm, Y. Shing, N. Fukai, G. Vasios, W.S. Lane, E. Flynn, J.R. Birkhead, B.R. Olsen, and J. Folkman Endostatin: an endogenous inhibitor of angiogenesis and tumor growth Cell 88 1997 277 285
2. M. Dhanabal, R. Ramchandran, M.J. Waterman, H. Lu, B. Knebelmann, M. Segal, and V.P. Sukhatme Endostatin induces endothelial cell apoptosis J. Biol. Chem. 274 1999 11721 11726
3. N. Yamaguchi, B. Anand-Apte, M. Lee, T. Sasaki, N. Fukai, R. Shapiro, I. Que, C. Lowik, R. Timpl, and B.R. Olsen Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding EMBO J. 18 1999 4414 4423
4. M. Dhanabal, R. Volk, R. Ramchandran, M. Simons, and V.P. Sukhatme Cloning, expression, and in vitro activity of human endostatin Biochem. Biophys. Res. Commun. 258 1999 345 352
5. A. Papapetropoulos, G. Garcia-Cardena, J.A. Madri, and W.C. Sessa Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells J. Clin. Invest. 100 1997 3131 3139
6. J.D. Hood, C.J. Meininger, M. Ziche, and H.J. Granger VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells Am. J. Physiol. 274 1998 H1054 H1058
7. Z.R. van der, T. Murohara, Z. Luo, F. Zollmann, J. Passeri, C. Lekutat, and J.M. Isner Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium Circulation 95 1997 1030 1037
8. L. Morbidelli, C.H. Chang, J.G. Douglas, H.J. Granger, F. Ledda, and M. Ziche Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium Am. J. Physiol. 270 1996 H411 H415
9. D. Shweiki, A. Itin, D. Soffer, and E. Keshet Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis Nature 359 1992 843 845
10. K.H. Plate, G. Breier, H.A. Weich, and W. Risau Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo Nature 359 1992 845 848
11. G. Breier, U. Albrecht, S. Sterrer, and W. Risau Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation Development 114 1992 521 532
12. W. Yang, J. Ando, R. Korenaga, T. Toyo-oka, and A. Kamiya Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells Biochem. Biophys. Res. Commun. 203 1994 1160 1167
13. R. Sarkar, R.C. Webb, and J.C. Stanley Nitric oxide inhibition of endothelial cell mitogenesis and proliferation Surgery 118 1995 274 279
14. A. RayChaudhury, H. Frischer, and A.B. Malik Inhibition of endothelial cell proliferation and bFGF-induced phenotypic modulation by nitric oxide J. Cell Biochem. 63 1996 125 134
15. J.E. Cartwright, A.P. Johnstone, and G.S. Whitley Endogenously produced nitric oxide inhibits endothelial cell growth as demonstrated using novel antisense cell lines Br. J. Pharmacol. 131 2000 131 137
16. O. Kosonen, H. Kankaanranta, P. Vuorinen, and E. Moilanen Inhibition of human lymphocyte proliferation by nitric oxide-releasing oxatriazole derivatives Eur. J. Pharmacol. 337 1997 55 61
17. E. Pipili-Synetos, A. Papageorgiou, E. Sakkoula, G. Sotiropoulou, T. Fotsis, G. Karakiulakis, and M.E. Maragoudakis Inhibition of angiogenesis, tumour growth and metastasis by the NO- releasing vasodilators, isosorbide mononitrate and dinitrate Br. J. Pharmacol. 116 1995 1829 1834
18. Y.T. Lau, and W.C. Ma Nitric oxide inhibits migration of cultured endothelial cells Biochem. Biophys. Res. Commun. 221 1996 670 674
19. J.S. Isenberg Nitric oxide modulation of early angiogenesis Microsurgery 24 2004 385 391
20. S. Donnini, and M. Ziche Constitutive and inducible nitric oxide synthase: role in angiogenesis Antioxid. Redox Signal. 4 2002 817 823
21. R.C. Venema Post-translational mechanisms of endothelial nitric oxide synthase regulation by bradykinin Int. Immunopharmacol. 2 2002 1755 1762
22. B.J. Michell, M.B. Harris, Z.P. Chen, H. Ju, V.J. Venema, M.A. Blackstone, W. Huang, R.C. Venema, and B.E. Kemp Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635 J. Biol. Chem. 277 2002 42344 42351
23. M.B. Harris, H. Ju, V.J. Venema, H. Liang, R. Zou, B.J. Michell, Z.P. Chen, B.E. Kemp, and R.C. Venema Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation J. Biol. Chem. 276 2001 16587 16591
24. S. Moncada Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin Br. J. Pharmacol. 76 1982 3 31
25. H. He, V.J. Venema, X. Gu, R.C. Venema, M.B. Marrero, and R.B. Caldwell Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src J. Biol. Chem. 274 1999 25130 25135
26. T. Murohara, J.R. Horowitz, M. Silver, Y. Tsurumi, D. Chen, A. Sullivan, and J.M. Isner Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin Circulation 97 1998 99 107
27. K. Ishii, H. Sheng, T.D. Warner, U. Forstermann, and F. Murad A simple and sensitive bioassay method for detection of EDRF with RFL-6 rat lung fibroblasts Am. J. Physiol. 261 1991 H598 H603
28. M.B. Harris, H. Ju, V.J. Venema, M. Blackstone, and R.C. Venema Role of heat shock protein 90 in bradykinin-stimulated endothelial nitric oxide release Gen. Pharmacol. 35 2000 165 170
29. V. Patel, C. Brown, A. Goodwin, N. Wilkie, and M.R. Boarder Phosphorylation and activation of p42 and p44 mitogen-activated protein kinase are required for the P2 purinoceptor stimulation of endothelial prostacyclin production Biochem. J. 320 1996 221 226
30. M.B. Harris, M.A. Blackstone, H. Ju, V.J. Venema, and R.C. Venema Heat-induced increases in endothelial NO synthase expression and activity and endothelial NO release Am. J. Physiol. Heart Circ. Physiol. 285 2003 H333 H340
31. W. Risau Mechanisms of angiogenesis Nature 386 1997 671 674
32. H.P. Gerber, V. Dixit, and N. Ferrara Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells J. Biol. Chem. 273 1998 13313 13316
33. H.P. Gerber, A. McMurtrey, J. Kowalski, M. Yan, B.A. Keyt, V. Dixit, and N. Ferrara Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation J. Biol. Chem. 273 1998 30336 30343
34. J. Folkman What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst. 82 1990 4 6
35. Y. Yokoyama, J.E. Green, V.P. Sukhatme, and S. Ramakrishnan Effect of endostatin on spontaneous tumorigenesis of mammary adenocarcinoma in a transgenic mouse model Cancer Res. 60 2000 4362 4365
36. G. Perletti, P. Concari, R. Giardini, E. Marras, F. Piccinini, J. Folkman, and L. Chen Antitumor activity of endostatin against carcinogen-induced rat primary mammary tumors Cancer Res. 60 2000 1793 1796
37. C. Urbich, A. Reissner, E. Chavakis, E. Dernbach, J. Haendeler, I. Fleming, A.M. Zeiher, M. Kaszkin, and S. Dimmeler Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin FASEB J. 16 2002 706 708
38. L. Jiang, V. Jha, M. Dhanabal, V.P. Sukhatme, and S.L. Alper Intracellular Ca(2+) signaling in endothelial cells by the angiogenesis inhibitors endostatin and angiostatin Am. J. Physiol. Cell Physiol. 280 2001 C1140 C1150
39. E. Spisni, C. Griffoni, S. Santi, M. Riccio, R. Marulli, G. Bartolini, M. Toni, V. Ullrich, and V. Tomasi Colocalization prostacyclin (PGI2) synthase-caveolin-1 in endothelial cells and new roles for PGI2 in angiogenesis Exp. Cell Res. 266 2001 31 43
40. L. Morbidelli, S. Donnini, F. Chillemi, A. Giachetti, and M. Ziche Angiosuppressive and angiostimulatory effects exerted by synthetic partial sequences of endostatin Clin. Cancer Res. 9 2003 5358 5369