Methyldibromo glutaronitrile contact allergy: Effect of single versus repeated daily exposure

Contact Dermatitis

Volumn 52, Issue 2, 2005, Pages 88-92

  Jensen, C D ^a,b   Johansen, J D ^b   Menne T ^b   Andersen, K E ^a,b  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Allergic contact dermatitis; Contact allergy; Methyldibromo glutaronitrile; Repeated daily application; Use test

Indexed keywords

2 BROMO 2 BROMOMETHYLGLUTARONITRILE; ALLERGEN; COSMETIC; NITRILE; UNCLASSIFIED DRUG;

ADULT; AGED; ALLERGIC REACTION; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTACT ALLERGY; CONTACT DERMATITIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EXPOSURE; FEMALE; FOREARM; HUMAN; MALE; PATCH TEST; RANDOMIZED CONTROLLED TRIAL; SENSITIZATION;

ADULT; AGED; AGED, 80 AND OVER; DERMATITIS, ALLERGIC CONTACT; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; NITRILES; PATCH TESTS; PRESERVATIVES, PHARMACEUTICAL; TREATMENT OUTCOME;

EID: 14844293179     PISSN: 01051873     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-1873.2005.00505.x     Document Type: Article

References (17)

1. Friedmann P S, Moss C, Shuster S, Simpson J M. Quantitative relationships between sensitizing dose of DNCB and reactivity in normal subjects. Clin Exp Immunol 1983: 53: 709-715.
2. Hextall J M, Alagaratnam N J, Glendinning A K et al. Dose-time relationships for elicitation of contact allergy to para-phenylenediamine. Contact Dermatitis 2002: 47: 96-99.
3. Andersen K E, Johansen J D, Bruze M et al. The time-dose-response relationship for elicitation of contact dermatitis in isoeugenol allergic individuals. Toxicol Appl Pharmacol 2001: 170: 166-171.
4. Johansen J D, Frosch P J, Svedman C et al. Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen. Contact Dermatitis 2003: 48: 310-316.
5. Lindelöf B. Regional variations of patch test response in nickel-sensitive patients. Contact Dermatitis 1992: 26: 202-203.
6. Kraus A L, Stotts J, Altringer L A, Allgood G S. Allergic contact dermatitis from propyl gallate: dose response comparison using various application methods. Contact Dermatitis 1990: 22: 132-136.
7. Marzulli F N, Maibach H I. Effects of vehicles and elicitation concentration in contact dermatitis testing. I. Experimental contact sensitization in humans. Contact Dermatitis 1976: 2: 325-329.
8. de Groot A C, de Cock P A, Coenraads P J et al. Methyldibromoglutaronitrile, is an important contact allergen in The Netherlands. Contact Dermatitis 1996: 34: 118-120.
9. van Ginkel C J, Rundervoort G J. Increasing incidence of contact allergy to the new preservative 1,2-dibromo-2, 4-dicyanobutane (methyldibromoglutaronitrile). Br J Dermatol 1995: 132: 918-920.
10. Tosti A, Vincenzi C, Trevisi P, Guerra L. Euxyl K 400: incidence of sensitization, patch test concentration and vehicle. Contact Dermatitis 1995: 33: 193-195.
11. Vigan M, Brechat P. Sensitization to Euxyl K400: a prospective study in 1217 patients. Eur J Dermatol 1996: 6: 175-177.
12. Wilkinson J D, Shaw S, Andersen K E et al. Monitoring levels of preservative sensitivity in Europe. A 10-year overview (1991-2000). Contact Dermatitis 2002: 46: 207-210.
13. Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for Consumers concerning methyldibromo glutaronitrile, Colipa no P77 2002.
14. Wahlberg J E. Patch testing. In: Textbook of Contact Dermatitis, Rycroft, R J G, Menné, T, Frosch, P J, Lepoittevin, J-P (eds), 3rd edition. Berlin: Springer-Verlag, 2001: 435-468.
15. McFadden J P, Wakelin Sh, Holloway D B, Basketter D A. The effect of patch duration on the elicitation of paraphenylenediamine contact allergy. Contact Dermatitis 1998: 39: 79-81.
16. Zachariae C, Rastogi S, Devantier C, Menné T, Johansen J D. Methyldibromo glutaronitrile: clinical experience and exposure-based risk assessment. Contact Dermatitis 2003: 48: 150-154.
17. Gerberick G F, Robinson M K. A skin sensitization risk assessment approach for evaluation of new ingredients and products. Am J Contact Dermat 2000: 11: 65-73.