Effects of cidofovir on cell death and replication of feline herpesvirus-1 in cultured feline corneal epithelial cells

American Journal of Veterinary Research

Volumn 66, Issue 2, 2005, Pages 217-222

  Sandmeyer, Lynne S ^a,b   Keller, Charlotte B ^a   Bienzle, Dorothee ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CIDOFOVIR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAT DISEASE; CELL COUNT; CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOPATHOLOGY; DRUG EFFICACY; DRUG MECHANISM; EPITHELIUM CELL; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IN VITRO STUDY; NONHUMAN; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CATS; CELL CULTURE TECHNIQUES; CELL DEATH; CELL SURVIVAL; CYTOPATHOGENIC EFFECT, VIRAL; CYTOSINE; DNA, VIRAL; EPITHELIUM, CORNEAL; HERPESVIRIDAE; IMMUNOHISTOCHEMISTRY; KERATIN-3; KERATINS; PHOSPHONIC ACIDS; POLYMERASE CHAIN REACTION; VIRUS REPLICATION;

ANIMALIA; FELIDAE; FELINE HERPESVIRUS 1; FELIS CATUS; HERPES; HERPESVIRIDAE; HERPESVIRUS 1; HUMAN HERPESVIRUS 1;

EID: 14844288317     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2005.66.217     Document Type: Article

References (34)

1. Nasisse MP, Guy JS, Davidson MG, et al. Experimental ocular herpesvirus infection in the cat. Sites of virus replication, clinical features and effects of corticosteroid administration. Invest Ophthalmol Vis Sci 1989;30:1758-1768.
2. Bistner SI, Carlson JH, Shively JN, et al. Ocular manifestations of feline herpesvirus infection. J Am Vet Med Assoc 1971;159:1223-1237.
3. Andrew SE. Ocular manifestations of feline herpesvirus. J Feline Med Surg 2001;3:9-16.
4. Nasisse MP. Feline herpesvirus ocular disease. Vet Clin North Am Small Anim Pract 1990;20:667-680.
5. De Clercq E. Comparative efficacy of antiherpes drugs in different cell lines. Antimicrob Agents Chemother 1982;21:661-663.
6. De Clercq E. The antiviral spectrum of (E)-5-(2-bromovinyl)-2′-deoxyuridine. J Antimicrob Chemother 1984;14(suppl A):85-95.
7. Stiles J. Feline herpesvirus. Vet Clin North Am Small Anim Pract 2000;30:1001-1014.
8. Sandmeyer LS, Keller, CB, Bienzle D. Culture of feline corneal epithelial cells and infection with feline herpesvirus-1 as an investigative tool. Am J Vet Res 2005;66:205-209.
9. Sandmeyer LS, Keller, CB, Bienzle D. Effect of interferon-α on cell death and replication of feline herpesvirus-1 in cultured feline corneal epithelial cells. Am J Vet Res 2005;66:217-222.
10. De Clercq E, Holy A. Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice. Antimicrob Agents Chemother 1991;35:701-706.
11. De Clercq E, Naesens L, De Bolle L, et al. Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8. Rev Med Virol 2001;11:381-395.
12. Gilliam SE, Field HJ. The effect of (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine (HPMPC) on bovine herpesvirus-1 (BHV-1) infection and reactivation in cattle. Antiviral Res 1993;20:21-32.
13. Gibson JS, Slater JD, Field HJ. The activity of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine (HPMPC) against equine herpesvirus-1 (EHV-1) in cell cultures, mice and horses. Antiviral Res 1992;19:219-232.
14. Kaufman HE, Varnell ED, Thompson HW. Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis. Arch Ophthalmol 1998;116:777-780.
15. Gordon YJ, Romanowski EG, Araullo-Cruz T. HPMPC, a broad-spectrum topical antiviral agent, inhibits herpes simplex virus type 1 replication and promotes healing of dendritic keratitis in the New Zealand rabbit ocular model. Cornea 1994;13:516-520.
16. Romanowski EG, Bartels SP, Gordon YJ. Comparative antiviral efficacies of cidofovir, trifluridine, and acyclovir in the HSV-1 rabbit keratitis model. Invest Ophthalmol Vis Sci 1999;40:378-384.
17. Maggs DJ, Clarke HE. In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1. Am J Vet Res 2004;65:399-403.
18. Ho HT, Woods KL, Bronson JJ, et al. Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonyl-methoxy)propyl]cytosine. Mol Pharmacol 1992;41:197-202.
19. Xiong X, Smith JL, Chen MS. Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation. Antimicrob Agents Chemother 1997; 41:594-599.
20. Cihlar T, Chen MS. Identification of enzymes catalyzing two-step phosphorylation of cidofovir and the effect of cytomegalovirus infection on their activities in host cells. Mol Pharmacol 1996; 50:1502-1510.
21. Aduma P, Connelly MC, Srinivas RV, et al. Metabolic diversity and antiviral activities of acyclic nucleoside phosphonates. Mol Pharmacol 1995;47:816-822.
22. Naesens L, de Clereq E. Therapeutic potential of HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogues as broad-spectrum antiviral agents. Nucleosides Nucleotides 1997;16:983-992.
23. Soike KF, Huang JL, Zhang JY, et al. Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonyl-methoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys. Antiviral Res 1991; 16:17-28.
24. Geggel HS, Gipson IK. Removal of viable sheets of conjunctival epithelium with dispase II. Invest Ophthalmol Vis Sci 1985;26:15-22.
25. Cooper D, Sun TT. Monoclonal antibody analysis of bovine epithelial keratins. Specific pairs as defined by coexpression. J Biol Chem 1986;261:4646-4654.
26. Grant RL, Acosta D. Comparative toxicity of tetracaine, proparacaine and cocaine evaluated with primary cultures of rabbit corneal epithelial cells. Exp Eye Res 1994;58:469-478.
27. Trocme SD, Hallberg CK, Gill KS, et al. Effects of eosinophil granule proteins on human corneal epithelial cell viability and morphology. Invest Ophthalmol Vis Sci 1997;38:593-599.
28. Schmidt NJ. Cell culture procedures for diagnostic virology. In: Schmidt NJ, Emmons RW, eds. Diagnostic procedures for viral, rickettsial, and chlamydial infections. 6th ed. Washington, DC: American Public Health Association, 1989;51-100.
29. Reed LJ, Muench HA. A simple method estimating fifty percent endpoints. Am J Hyg 1938;27:243-297.
30. VanDevanter DR, Warrener P, Bennett L, et al. Detection and analysis of diverse herpesviral species by consensus primer PCR. J Clin Microbiol 1996;34:1666-1671.
31. SAS/STAT user's guide, version 8. Cary, NC: SAS Institute Inc, 1999;3884.
32. SAS procedures guide, version 8. Cary, NC: SAS Institute Inc, 1999;1675.
33. Cox DR, Snell EJ. Special logistic analysis. In: Cox DR, Snell EJ, eds. Analysis of binary data. 2nd ed. London: Chapman and Hall, 1989;26-105.
34. Neyts J, Snoeck R, Schols D, et al. Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine. Virology 1990;179:41-50.