Glucose, lactate, and pyruvate concentrations in dogs with babesiosis

American Journal of Veterinary Research

Volumn 66, Issue 2, 2005, Pages 244-250

  Jacobson, Linda S ^a,b   Lobetti, Remo G ^a,c  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b Bryanston Veterinary Hospital ^*  (Canada)

^c Bryanston Veterinary Hospital   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BIOLOGICAL MARKER; CREATININE; GLUCOSE; LACTIC ACID; PYRUVIC ACID; UREA;

ACID BASE BALANCE; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BABESIOSIS; BLOOD ANALYSIS; BLOOD CELL COUNT; BLOOD SAMPLING; BLOOD SMEAR; CARBOHYDRATE METABOLISM; CLINICAL FEATURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DEATH; DISEASE SEVERITY; DOG DISEASE; FEMALE; HYPERLACTATEMIA; HYPOGLYCEMIA; LABORATORY TEST; MALE; NONHUMAN; PARASITEMIA; QUANTITATIVE ANALYSIS; SURVIVAL RATE;

ACID-BASE EQUILIBRIUM; ANIMALS; BABESIOSIS; BLOOD GAS ANALYSIS; BLOOD GLUCOSE; BLOOD PRESSURE DETERMINATION; DOG DISEASES; DOGS; HYPOGLYCEMIA; LACTIC ACID; PROSPECTIVE STUDIES; PYRUVIC ACID; URINALYSIS;

ANIMALIA; CANIS FAMILIARIS;

EID: 14844286947     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2005.66.244     Document Type: Article

References (60)

1. Mizock BA. Alterations in carbohydrate metabolism during stress: a review of the literature. Am J Med 1995;98:75-84.
2. De Papp E, Drobatz KJ, Hughes D, et al. Plasma lactate concentration as a predictor of gastric necrosis and survival among dogs with gastric dilatation-volvulus: 102 cases (1995-1998). J Am Vet Med Assoc 1999;215:49-52.
3. Mizock BA, Falk JL. Lactic acidosis in critical illness. Crit Care Med 1992;20:80-93.
4. Breitschwerdt EB, Loar AS, Hribernik TN, et al. Hypoglycemia in four dogs with sepsis. J Am Vet Med Assoc 1981;178:1072-1076.
5. Griffiths J, Groves AC, Leung FY. Hypertriglyceridemia and hypoglycemia in gram-negative sepsis in the dog. Surg Gynecol Obstet 1973;136:897-903.
6. Hardie EM, Rawlings CA, George JW. Plasma-glucose concentrations in dogs and cats before and after surgery: comparison of healthy animals and animals with sepsis. Am J Vet Res 1985;46:1700-1704.
7. Marretta SM, Matthiesen DT, Nichols R. Pyometra and its complications. Probl Vet Med 1989;1:50-62.
8. Matthiesen DT, Marretta SM. Complications associated with the surgical treatment of prostatic abscessation. Probl Vet Med 1989;1:63-73.
9. Jacobs RM, Weiser MG, Hall RL, et al. Clinicopathologic features of canine parvoviral enteritis. J Am Anim Hosp Assoc 1980;16:809-814.
10. Barr SC, Gossett KA, Klei TR. Clinical, clinicopathologic, and parasitologic observations of trypanosomiasis in dogs infected with North American Trypanosoma cruzi isolates. Am J Vet Res 1991; 52:954-960.
11. Kitoh K, Watoh K, Chaya K, et al. Clinical, hematologic, and biochemical findings in dogs after induction of shock by injection of heartworm extract. Am J Vet Res 1994;55:1535-1541.
12. Macintire DK, Vincent-Johnson N, Dillon AR, et al. Hepatozoonosis in dogs: 22 cases (1989-1994). J Am Vet Med Assoc 1997;210:916-922.
13. Reina D, Habela M, Navarrete I, et al. Hypoglycaemia in experimental canine trichinellosis. Vet Parasitol 1989;33:289-296.
14. Elliott WH, Elliott DC. Glycolysis, the citric acid cycle, and the electron transport system:reactions involved in these pathways. In: Elliot WH, Elliot DC, eds. Biochemistry and molecular biology. Oxford: Oxford University Press, 1997;107-129.
15. Dennis SC, Gevers W, Opie LH. Protons in ischemia: where do they come from; where do they go to? J Mol Cell Cardiol 1991;23:1077-1086.
16. Hotchkiss RS, Karl IE. Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis. JAMA 1992;267:1503-1510.
17. Uilenberg G, Franssen F, Perie NM, et al. Three groups of Babesia canis distinguished and a proposal for nomenclature. Vet Q 1989;11:33-40.
18. Collett MG. Survey of canine babesiosis in South Africa. J S Afr Vet Assoc 2000;71:180-186.
19. Maegraith B, Gilles HM, Devakul K. Pathological processes in Babesia canis infections. Z Tropenmed Parasitol 1957;8:485-514.
20. Welzl C, Leisewitz AL, Jacobson LS, et al. Systemic inflammatory response syndrome and multiple organ damage/dysfunction in complicated canine babesiosis. J S Afr Vet Assoc 2001;72:158-162.
21. Molyneux ME, Taylor TE, Wirima JJ, et al. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q J Med 1989;71:441-459.
22. White NJ, Warrell DA, Chanthavanich P, et al. Severe hypeglycemia and hyperinsulinemia in falciparum malaria. N Engl J Med 1983;309:61-66.
23. Day NP, Phu NH, Mai NT, et al. The pathophysiologic and prognostic significance of acidosis in severe adult malaria. Crit Care Med 2000;28:1833-1840.
24. Davis TME, Benn JJ, Suputtamongkil Y, et al. Lactate turnover and forearm lactate metabolism in severe falciparum malaria. Endocrinol Metab 1996;3:105-115.
25. Wright IG, Waltisbuhl DJ, Mahoney DF, et al. Acute Babesia bovis infections: metabolic and blood gas changes during infection. Br Vet J 1982;138:61-69.
26. Keller N, Jacobson LS, Nel M, et al. Prevalence and risk factors of hypoglycemia in virulent canine babesiosis. J Vet Intern Med 2004;18:265-270.
27. Cohen RD, Woods HF. The clinical presentations and classifications of lactic acidosis. In: Cohen RD, Woods HF, eds. Clinical and biochemical aspects of lactic acidosis. Oxford: Blackwell Scientific Publications, 1976;40-63.
28. Mizock BA. The hepatosplanchnic area and hyperlactatemia: a tale of two lactates. Crit Care Med 2001;29:447-449.
29. Button C. Metabolic and electrolyte disturbances in acute canine babesiosis. J Am Vet Med Assoc 1979;175:475-479.
30. Leisewitz AL, Jacobson LS, De Morais HS, et al. The mixed acid-base disturbances of severe canine babesiosis. J Vet Intern Med 2001;15:445-452.
31. Nel M, Lobetti RG, Keller N, et al. Prognostic value of blood lactate, blood glucose, and hematocrit in canine babesiosis. J Vet Intern Med 2004;18:471-476.
32. Jacobson LS, Clark IA. The pathophysiology of canine babesiosis: new approaches to an old puzzle. J S Afr Vet Assoc 1994;65:134-145.
33. Jacobson LS, Lobetti RG, Vaughan-Scott T. Blood pressure changes in dogs with babesiosis. J S Afr Vet Assoc 2000;71:14-20.
34. Czok R, Lamprecht W. Pyruvate, phosphoenolpyruvate and D-glycerate-2-phosphate. In: Bergmeyer HU, ed. Methods of enzymatic analysis. New York: Academic Press Inc, 1974; 1446-1451.
35. Moore DJ, Williams MC. Disseminated intravascular coagulation: a complication of Babesia canis infection in the dog. J S Afr Vet Assoc 1979;50:265-275.
36. Adams J, Hazard P. Comparison of blood lactate concentrations in arterial and peripheral venous blood. Crit Care Med 1988;16:913-914.
37. Oliva PB. Lactic acidosis. Am J Med 1970;48:209-225.
38. Deshpande SA, Platt M. Association between blood lactate and acid-base status and mortality in ventilated babies. Arch Dis Child Fetal Neonatal Ed 1997;76:F15-F20.
39. English M, Sauerwein R, Waruiru C, et al. Acidosis in severe childhood malaria. QJM 1997;90:263-270.
40. Bakker J, Gris P, Coffernils M, et al. Serial blood lactate levels can predict the development of multiple organ failure following septic shock. Am J Surg 1996;171:221-226.
41. Howerton TL, Shell LG. Neurologic manifestations of altered serum glucose. Prog Vet Neurol 1992;3:57-64.
42. Davis TME, Looareesuwan S, Pukrittayakamee S, et al. Glucose turnover in severe falciparum malaria. Metabolism 1993;42:334-340.
43. Holloway PA, Krishna S, White NJ. Plasmodium berghei: lactic acidosis and hypoglycaemia in a rodent model of severe malaria; effects of glucose, quinine, and dichloroacetate. Exp Parasitol 1991;72:123-133.
44. Groves AC, Woolf LI, O'Regan PJ, et al. Impaired gluconeogenesis in dogs with E. coli bacteraemia. Surgery 1974;76:533-541.
45. Gilbert VE. Blood pyruvate and lactate during febrile human infections. Metabolism 1968;17:943-951.
46. Krishna S, Supanaranond W, Pukrittayakamee S, et al. Dichloroacetate for lactic acidosis in severe malaria: a pharmacokinetic and pharmacodynamic assessment. Metabolism 1994;43:974-981.
47. Reyers F, Leisewitz AL, Lobetti RG, et al. Canine babesiosis in South Africa - more than one disease. Does this serve as a model for falciparum malaria? Ann Trop Med Parasitol 1998;92:503-511.
48. Hauptman JG, Tvedten H. Osmolal and anion gaps in dogs with acute endotoxic shock. Am J Vet Res 1986;47:1617-1619.
49. Huckabee WE. Abnormal resting lactate. II. Lactic acidosis. Am J Med 1961;6:840-848.
50. Meszaros K, Lang CH, Bagby GJ, et al. Tumor necrosis factor increases in vivo glucose utilization of macrophage-rich tissues. Biochem Biophys Res Commun 1987;149:1-6.
51. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;101:1644-1655.
52. Basson PA, Pienaar JG. Canine babesiosis: a report on the pathology of three cases with special reference to the 'cerebral' form. J S Afr Vet Med Assoc 1965;36:333-341.
53. Taylor JH, Guthrie AJ, Van der Walt JG, et al. The effect of Babesia canis induced haemolysis on the canine haemoglobin oxygen dissociation curve. J S Afr Vet Assoc 1993;64:141-143.
54. Lobetti R, Dvir E, Pearson J. Cardiac troponins in canine babesiosis. J Vet Intern Med 2002;16:63-68.
55. Elased KM, Playfair J. Reversal of hypoglycaemia in murine malaria by drugs that inhibit insulin secretion. Parasitology 1996;112:515-521.
56. Dekker E, Romijn JA, Waruiru C, et al. The relationship between glucose production and plasma glucose concentration in children with falciparum malaria. Trans R Soc Trop Med Hyg 1996;90:654-657.
57. McGuinness OP. The impact of infection on gluconeogenesis in the conscious dog. Shock 1994;2:336-343.
58. Malherbe WD. Clinico-pathological studies of Babesia canis infection in dogs. I. The influence of the infection on bromsulphalein retention in the blood. J S Afr Vet Med Assoc 1965;36:25-29.
59. Krishna S, Waller DW, Ter Kuile F, et al. Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance. Trans R Soc Trop Med Hyg 1994; 88:67-73.
60. Gore DC, Jahoor F, Hibbert JM, et al. Lactic acidosis during sepsis is related to increased pyruvate production, not deficits in tissue oxygen availability. Ann Surg 1996;224:97-102.