FISH analysis of all fetal nucleated cells in maternal whole blood: Improved specificity by the use of two Y-chromosome probes

Journal of Histochemistry and Cytochemistry

Volumn 53, Issue 3, 2005, Pages 319-322

  Mergenthaler, Susanne ^b   Babochkina, Tatiana ^b   Kiefer, Vivian ^b   Lapaire, Olaf ^a   Holzgreve, Wolfgang ^a,b   Hahn, Sinuhe ^a,b  

^a UNIVERSITY WOMEN S HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Carnoy; Entire fetal cell population; FISH; Noninvasive prenatal diagnosis

Indexed keywords

CONFERENCE PAPER; CONTROLLED STUDY; CYTOGENETICS; FETUS; FETUS CELL; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALE; MATERNAL BLOOD; NONINVASIVE PRENATAL DIAGNOSIS; NUCLEOTIDE SEQUENCE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UMBILICAL CORD BLOOD; X CHROMOSOME; Y CHROMOSOME;

EID: 14844285385     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.4A6404.2005     Document Type: Conference Paper

References (9)

1. Bianchi DW, Romero R (2003) Biological implications of bi-directional fetomaternal cell traffic: a summary of a National Institute of Child Health and Human Development-sponsored conference. J Matern Fetal Neonatal Med 14:123-129
2. Bianchi DW, Simpson JL, Jackson LG, Elias S, Holzgreve W, Evans MI, Dukes KA, et al. (2002) Fetal gender and aneuploidy detection using fetal cells in maternal blood: analysis of NIFTY I data. National Institute of Child Health and Development Fetal Cell Isolation Study. Prenat Diagn 22:609-615
3. Bianchi DW, Williams JM, Sullivan LM, Hasnon FW, Klinger KW, Shuber AP (1997) PCR quantification of fetal cells in maternal blood in normal and aneuploid pregnancies. Am J Hum Genet 61:822-829
4. Hahn S, Holzgreve W (2002) Prenatal diagnosis using fetal cells and cell-free fetal DNA in maternal blood: what is currently feasible? Clin Obstet Gynecol 45:649-656
5. Hamada H, Arinami T, Kubo T, Hamaguchi H, Iwasaki H (1993) Fetal nucleated cells in maternal peripheral blood: frequency and relationship to gestational age. Hum Genet 91:427-432
6. Hamada H, Arnami T, Sohda S, Hamaguchi H, Kubo T (1995) Mid-trimester fetal sex determination from maternal peripheral blood by fluorescence in situ hybridization without enrichment of fetal cells. Prenat Diagn 15:78-81
7. Hromadnikova I, Karamanov S, Houbova B, Hridelova D, Jofer J, Mrstinova M (2002) Non-invasive fetal sex determination on fetal erythroblasts from the maternal circulation using fluorescence in situ hybridisation. Fetal Diagn Ther 17:193-199
8. Krabchi K, Gros-Louis F, Yan J, Bronsard M, Massé J, Forest J-C, Drouin R (2001) Quantification of all fetal nucleated cells in maternal blood between the 18th and 22nd weeks of pregnancy using molecular cytogenetic techniques. Clin Genet 60:145-150
9. Zhong XY, Laivuori H, Livingston JC, Ylikorkala O, Sibai BM, Holzgreve W, Hahn S (2001) Elevation of both maternal and fetal extracellular circulating deoxyribonucleic acid concentrations in the plasma of pregnant women with preeclampsia. Am J Obstet Gynecol 184:414-419