The role of antibiotic prophylaxis in clean incised hand injuries: A prospective randomized placebo controlled double blind trial

Journal of Hand Surgery

Volumn 30, Issue 2, 2005, Pages 162-167

  Whittaker, J P ^a,b   Nancarrow, J D ^a   Sterne, G D ^a  

^a Wordsley Hospital   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

Hand; Infection; Injury; Prophylactic antibiotics

Indexed keywords

ANTIBIOTIC AGENT; FLUCLOXACILLIN; PLACEBO;

ADOLESCENT; ADULT; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BACILLUS CEREUS; BACTERIUM CONTAMINATION; BETA HEMOLYTIC STREPTOCOCCUS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG RESPONSE; DRUG WITHDRAWAL; FEMALE; FINGER INJURY; FOLLOW UP; HAND INJURY; HUMAN; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE INFECTION; RANDOMIZED CONTROLLED TRIAL; STAPHYLOCOCCUS AUREUS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; THUMB INJURY; WOUND INFECTION; WRIST INJURY;

ADOLESCENT; ADULT; AGED; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; FLOXACILLIN; GRAM-POSITIVE BACTERIA; HAND INJURIES; HUMANS; MALE; MIDDLE AGED; PREOPERATIVE CARE; PROSPECTIVE STUDIES; SURGICAL WOUND INFECTION;

EID: 14744301569     PISSN: 02667681     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhsb.2004.10.015     Document Type: Article

References (15)

1. J.N. Brown An audit of prophylactic antibiotic prescribing patterns in orthopaedic practice Journal Royal College of Surgeons of Edinburgh 39 1994 55-59
2. M. Callaham Controversies in antibiotic choices for bite wounds Annals of Emergency Medicine 17 1988 1321-1330
3. J.E. Conte Jr S.N. Cohen B.B. Roe et al. Antibiotic prophylaxis and cardiac surgery: A prospective double-blind comparison of single-dose versus multiple-dose regimens Annals of Internal Medicine 76 1972 943-949
4. P. Cummings Antibiotics to prevent infection in patients with dog bite wounds: A meta-analysis of randomised controlled trials Annals of Emergency Medicine 23 1994 535-540
5. P.J. Drew O.G. Titley Use of antibiotics after complex open hand injury British Journal Clinical Pharmacology 49 1995 297-300
6. R.M. Elenbaas W.K. McNabney W.A. Robinson Evaluation of prophylactic oxacillin in cat bite wounds Annals of Emergency Medicine 13 1984 155-157
7. J.A.I. Grossman J.P. Adams J. Kunec Prophylactic antibiotics in simple hand lacerations Journal American Medical Association 245 1981 1055-1056
8. R.D. Hoffman B.D. Adams The role of antibiotics in the management of elective and post-traumatic hand surgery Hand Clinics 14 1998 657-666
9. J.M. Kleinert J. Hoffmann C.G. Miller et al. Postoperative infection in a double-occupancy operating room: A prospective study of two thousand four hundred and fifty-eight procedures on the extremities Journal of Bone and Joint Surgery 79A 1997 503-513
10. A.L.G. Peel E.W. Taylor Proposed definitions for the audit of postoperative infection: A discussion paper Annals of Royal College of Surgeons of England 73 1991 385-388
11. A.J. Platt R.E. Page Post-operative infection following hand surgery: guidelines for antibiotic use Journal of Hand Surgery 20B 1995 685-690
12. A.H.N. Roberts P.J. Teddy A prospective trial of prophylactic antibiotics in hand lacerations British Journal of Surgery 64 1977 394-396
13. D.B. Shapiro Postoperative infection in hand surgery Hand Clinics 14 1998 669-681
14. J.P. Sloan A.F. Dove M. Maheson et al. Antibiotics in open fractures of the distal phalanx Journal of Hand Surgery 12B 1987 123
15. V.N. Zubowicz M. Gravier Management of early human bites of the hand: A prospective randomised study Plastic and Reconstructive Surgery 88 1991 111