By-passing immunization: Building high affinity human antibodies by chain shuffling

Bio/Technology

Volumn 10, Issue 7, 1992, Pages 779-783

  Marks, James D ^a   Griffiths, Andrew D ^a   Malmqvist, Magnus ^a   Clackson, Tim P ^a   Bye, Jacqueline M ^a,b   Winter, Greg ^a,c  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

ARTICLE; BIOTECHNOLOGY; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BIOTECHNOLOGY; COMPARATIVE STUDY; GENE LIBRARY; GENES, IMMUNOGLOBULIN; HUMAN; IMMUNIZATION; IMMUNOGLOBULINS, HEAVY-CHAIN; IMMUNOGLOBULINS, LIGHT-CHAIN; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T;

EID: 14744300211     PISSN: 0733222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0792-779     Document Type: Article

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