Reduced oxidative metabolic response in dysfunctional myocardium with preserved glucose metabolism but with impaired contractile reserve

Journal of Nuclear Medicine

Volumn 45, Issue 11, 2004, Pages 1885-1891

  Yoshinaga, Keiichiro ^a   Katoh, Chietsugu ^a   Beanlands, Rob S B ^b   Noriyasu, Kazuyuki ^a   Komuro, Kaoru ^a   Yamada, Satoshi ^a   Kuge, Yuji ^a   Morita, Koichi ^a   Kitabatake, Akira ^a   Tamaki, Nagara ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Coronary disease; Dobutamine; Hibernation; Oxidative metabolism; Tomography

Indexed keywords

ACETIC ACID C 11; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; DOBUTAMINE; FLUORODEOXYGLUCOSE F 18; NITRIC ACID DERIVATIVE; ACETIC ACID DERIVATIVE; CARBON; CARBON 11 ACETATE; CARBON-11 ACETATE; DIAGNOSTIC AGENT; GLUCOSE; OXYGEN; RADIOPHARMACEUTICAL AGENT;

ADULT; AEROBIC METABOLISM; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FEMALE; GLUCOSE METABOLISM; HEART CONTRACTION; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE PERFUSION; HEMODYNAMICS; HUMAN; MALE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RISK REDUCTION; CLINICAL TRIAL; COMPARATIVE STUDY; HEART; METABOLIC CLEARANCE RATE; METABOLISM; MIDDLE AGED; SCINTISCANNING; STUNNED HEART MUSCLE;

ACETATES; CARBON; FEMALE; GLUCOSE; HEART; HUMANS; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL STUNNING; MYOCARDIUM; OXYGEN; RADIOPHARMACEUTICALS;

EID: 14744298196     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Wijns W, Vatner SF, Camici PG. Hibernating myocardium. N Engl J Med. 1998;339:173-181.
2. Schelbert HR. Positron emission tomography for the assessment of myocardial viability. Circulation. 1991;84(suppl I):122-131.
3. Afridi I, Kleiman NS, Raizner AE, et al. Dobutamine echocardiography in myocardial hibernation: optimal dose and accuracy in predicting recovery of ventricular function after coronary angiography. Circulation. 1995;91:663-670.
4. Baer FM, Voth E, Schneider CA, et al. Dobutamine-gradient echo MRI: a functional and morphologic approach to the detection of residual myocardial viability. Circulation. 1995;91:1006-1015.
5. Tamaki N, Yonekura Y, Yamashita K, et al. Positron emission tomography using fluorine-18-fluorodeoxyglucose in evaluation of coronary artery bypass grafting. Am J Cardiol. 1989;64:860-865.
6. Yoshinaga K, Morita K, Yamada S, et al. Low-dose dobutamine electrocardiograph-gated myocardial SPECT for identifying viable myocardium: comparison with dobutamine stress echocardiography and PET. J Nucl Med. 2001;42:838-844.
7. Pagano D, Townend JN, Littler WA, Horton R, Camici PG, Bonser RS. Coronary artery bypass surgery as treatment for ischemic heart failure: the predictive value of viability assessment with quantitative positron emission tomography for symptomatic and functional outcome. J Thorac Cardiovasc Surg. 1998;115:791-799.
8. 18F-FDG SPECT using acipimox for the assessment of myocardial viability. J Nucl Med. 2003;44:877-883.
9. Bax JJ, Poldermans D, Elhendy A, Boersma E, Rahimtoola SH. Sensitivity, specificity, and predictive accuracies of various noninvasive techniques for detecting hibernating myocardium. Curr Probl Cardiol. 2001;26:141-186.
10. Pierard L, De Landsheere CM, Berthe C, et al. Identification of viable myocardium by echocardiography during dobutamine infusion in patients with myocardial infarction after thrombolytic therapy: comparison with positron emission tomography. J Am Coll Cardiol. 1990;15:1021-1031.
11. Baer FM, Voth E, Deutsch HJ, et al. Assessment of viable myocardium by dobutamine transesophageal echocardiography and comparison with fluorine-18-fluorodeoxyglucose positron emission tomography. J Am Coll Cardiol. 1994;24:343-353.
12. Brown M, Marshall DR, Sobel BE, et al. Delineation of myocardial oxygen utilization with carbon-11-labelaed acetate. Circulation. 1987;76:687-696.
13. Gropler RJ, Geltman EM, Sampathkumaran K, et al. Functional recovery after coronary revascularization for chronic coronary artery disease is dependent on maintenance of oxidative metabolism. J Am Coll Cardiol. 1992;20:569-577.
14. Gropler RJ, Geltman EM, Sampathkumaran K, et al. Comparison of carbon-11-acetate with fluorine-18-fluorodeoxyglucose for delineating viable myocardium by positron emission tomography. J Am Coll Cardiol. 1993;22:1587-1597.
15. Hata T, Nohara R, Fujita M, et al. Noninvasive assessment of myocardial viability by positron emission tomography with C-11 acetate in patients with old myocardial infarction: usefulness of low-dose dobutamine infusion. Circulation. 1996;94:1834-1841.
16. Lee HH, Davila-Roman VG, Ludbrook PA, et al. Dependency of contractile reserve on myocardial blood flow: implications for the assessment of myocardial viability with dobutamine stress echocardiography. Circulation. 1997;96:2884-2891.
17. Tamaki N, Magata Y, Takahashi N, et al. Oxidative metabolism in the myocardium in normal subjects during dobutamine infusion. Eur J Nucl Med. 1993;20:231-237.
18. 11C) acetate: an agent for the study of myocardial metabolism by positron emission tomography. Int J Appl Radiat Isot. 1982;33:505-512.
19. 2 PET for the assessment of myocardial oxygen utilization in patients with chronic myocardial infarction. Eur J Nucl Med. 2001;28:334-339.
20. Schiller NB, Shah PM, Crawford M, et al. American Society of Echocardiography Committee on Standards: Subcommittee on Quantitation of Two-Dimensional Echocardiograms - Recommendations for quantification of the left ventricle by two-dimensional echocardiography. J Am Soc Echocardiogr. 1989;5:358-367.
21. Rimoldi O, Burns SM, Rosen SD, et al. Measurement of myocardial blood flow with positron emission tomography before and after transmyocardial laser revascularization. Circulation. 1999;100(suppl II):134-138.
22. Beanlands RSB, Nahmias C, Gordon E, et al. The effects of β1-blockade on oxidative metabolism and the metabolic cost of ventricular work in patients with left ventricular dysfunction: a double-blind, placebo-controlled, positron emission tomography study. Circulation. 2000;102:2070-2075.
23. Armbrecht JJ, Buxton DB, Brunken RC, et al. Regional myocardial oxygen consumption determined noninvasively in humans with (C-11) acetate and dynamic positron tomography. Circulation. 1989;80:863-872.
24. Gropler RJ, Siegel BA, Geltman EM. Myocardial uptake of carbon-11-acetate as an indirect estimate of regional myocardial blood flow. J Nucl Med. 1991;32:245-251.
25. Matsunari I, Fujino S, Taki J, et al. Quantitative rest technetium-99m tetrofosmin imaging in predicting functional recovery after revascularization: comparison with rest-redistribution thallium-201. J Am Coll Cardiol. 1997;29:1226-1233.
26. Maes AF, Werf FVD, Mesitten LV, et al. Early assessment of regional myocardial blood flow and metabolism in thrombolysis in myocardial infarction flow grade 3 reperfused myocardial infarction using carbon-11-acetate. J Am Coll Cardiol. 2001;37:30-36.
27. Germano G, Kiat H, Kavanagh PB, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995;36:2138-2147.
28. Cornel JH, Bax JJ, Elhendy A, et al. Agreement and disagreement between "metabolic viability" and "contractile reserve" in akinetic myocardium. J Nucl Cardiol. 1999;6:383-388.
29. Bax JJ, Poldermans D, Visser FC, et al. Delayed recovery of hibernating myocardium after surgical revascularization: implications for discrepancy between metabolic imaging and dobutamine echocardiography for assessment of myocardial viability. J Nucl Cardiol. 1999;6:685-687.
30. Camici PG, Dutka DP. Repetitive stunning, hibernation, and heart failure: contribution of PET to establishing a link. Am J Physiol Heart Circ Physiol. 2001;280:H929-H936.
31. Vanoverschelde JLJ, Melin JA, Bol A, et al. Regional oxidative metabolism in patients after recovery from reperfused anterior myocardial infarction. Circulation. 1992;85:9-21.
32. Budinger GRS, Duranteaus J, Chandel NS, et al. Hibernation during hypoxia in cardiomyocytes. J Biol Chem. 1998;273:3320-3326.
33. Krivokapich J, Huang SC, Schelbert HR. Assessment of the effects of dobutamine on myocardial blood flow and oxidative metabolism in normal human subjects using nitrogen-13 ammonia and carbon-11 acetate. Am J Cardiol. 1993;71:1351-1356.
34. Baumgartner H, Porenta G, Lau YK, et al. Assessment of myocardial viability by dobutamine echocardiography, positron emission tomography and thallium-201 SPECT: correlation with histopathology in explanted hearts. J Am Coll Cardiol. 1998;32:1701-1708.
35. Elsasser A, Schlepper M, Klovekorn WP, et al. Hibernating myocardium: an incomplete adaptation to ischemia. Circulation. 1997;96:2920-2931.
36. Nagueh SF, Mikati I, Weilbaecher D, et al. Relation of the contractile reserve of hibernating myocardium to myocardial structure in humans. Circulation. 1999;100:490-496.