Optimized CMOS photodetector structures for the detection of green luminescent probes in biological applications

Sensors and Actuators, B: Chemical

Volumn 103, Issue 1-2, 2004, Pages 43-49

  Yotter, R A ^a   Warren, M R ^a   Wilson, D M ^a  

^a University of Washington   (United States)

Author keywords

CMOS; Fluorescence detector; Photodetector; Photodiode; Stripe shaped photodiode

Indexed keywords

CATHODES; CMOS INTEGRATED CIRCUITS; DIFFUSION; DOPING (ADDITIVES); INTEGRAL EQUATIONS; LIGHT ABSORPTION; MICROPROCESSOR CHIPS; OPTIMIZATION; PHOTODIODES; PROBES; QUANTUM EFFICIENCY; SIGNAL TO NOISE RATIO;

CMOS TECHNOLOGY; FLUORESCENCE DETECTORS; GAUSSIAN DOPING; STRIPE-SHAPED PHOTODIODES;

PHOTODETECTORS;

EID: 14744287491     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2004.04.035     Document Type: Conference Paper

References (18)

1. D.R. Meldrum, S.E. Moody, Automating high-throughput fluid sample handling for biotechnology and chemistry, in: Proceedings of the IEEE International Conference on Robotics & Automation, San Francisco, CA, 2000, 198-205.
2. D.R. Meldrum, W.H. Pence, S.E. Moody, D.L. Cunningham, M. Holl, P.J. Wiktor, Automated Microfluidics for Genomics, in: Proceedings of the 23rd Annual EMBS International Conference, Istanbul, Turkey, 25-28 October 2001, pp. 2923-2926.
3. Burns M.A., Johnson B.N., Brahmasandra S.N., Handique K., Webster J.R., Krishnan M., Sammarco T.S., Man P.F., Jones D.K., Heldsinger D., Mastrangelo C.H., Burke D.T. An integrated nanoliter DNA analysis device. Science. 282:1998;484-487
4. Selvaganapathy P.R., Carlen E.T., Mastrangelo C.H. Recent progress in microfluidic devices for nucleic acid and antibody assays. Proc. IEEE. 91:2003;954-975
5. Mastrangelo C.H., Burns M.A., Burke D.T. Microfabricated devices for genetic diagnostics. Proc. IEEE. 86:1998;1769-1787
6. J.R. Webster, C.H. Mastrangelo, Large-volume integrated capillary electrophoresis stage fabricated using micromachining of plastics on silicon substrates, in: TRANSDUCERS '97, Chicago, IL, 1997, pp. 503-506.
7. K.D. Kramer, K.W. Oh, C.H. Ahn, J.J. Bao, K.R. Wehmeyer, Optical MEMS-based fluorescence detection scheme with applications to capillary electrophoresis, in: Proceedings of the SPIE - Conference on Microfluidic Development Systems, Santa Clara, CA, 1998, pp. 76-85.
8. Wilson D.M., Hoyt S., Janata J., Booksh K., Obando L. Chemical sensors for portable, handheld field instruments. IEEE Sens. J. 1:2001;256-274
9. D. Meldrum, M. Holl, P. Seriburi, S. Phillips, S.H. Chao, L. Lang, F. Kosar, MEMS modules for life-on-a-chip, in: Proceedings of the 2003 International Symposium Circuits Systems, ISCAS, Bangkok, Thailand, 2003, pp. 638-641.
10. Yotter R.A., Wilson D.M. A review of photodetectors for sensing light-emitting reporters in biological systems. IEEE Sens. J. 3:2003;288-303
11. Pauchard A., Besse P.-A., Popovic R.S. A silicon blue/UV selective stripe-shaped photodiode. Sens. Actuators A. 76:1999;172-177
12. Yin C.S. The p-i-n junction-surface depletion-layer photodiode. IEEE Elect. Dev. Lett. 12:1991;442-443
13. Simpson M.L., Sayler G.S., Applegate B.M., Ripp S., Nivens D.E., Paulus M.J., Jellison G.E. Jr. Bioluminescent-bioreporter integrated circuits form novel whole-cell biosensors. Trends Biotechnol. 16:1998;332-338
14. Simpson M.L., Sayler G.S., Patterson G., Nivens D.E., Bolton E.K., Rochelle J.M., Arnott J.C., Applegate B.M., Ripp S., Guillorn M.A. An integrated CMOS microluminometer for low-level luminescence sensing in the bioluminescence bioreporter integrated circuit. Sens. Actuators B. 72:2001;134-140
15. Bolton E.K., Sayler G.S., Nivens D.E., Rochelle J.M., Ripp S., Simpson M.L. Integrated CMOS photodetectors and signal processing for very low-level chemical sensing with the bioluminescent bioreporter integrated circuit. Sens. Actuators. 85:2002;179-185
16. Molecular Probes Inc. (Online). Data Table-8.1 Nucleic Acid Stains. Available: http://www.probes.com/servlets/datatable?id=32237. 10 September 2003 (date accessed).
17. Molecular Probes Inc. (Online). Data Table-21.2 Probes Useful at Near-Neutral pH. Available: http://www.probes.com/servlets/datatable?id=28859. 10 September 2003 (date accessed).
18. Molecular Probes Inc. (Online). Data Table-15.2 Viability and Cytotoxicity Assay Reagents. Available: http://www.probes.com/servlets/ datatable?id=29279. 10 September 2003 (date accessed).