A New Tobacco Mosaic Virus Vector and its Use for the Systemic Production of Angiotensin-I-Converting Enzyme Inhibitor in Transgenic Tobacco and Tomato

Bio/Technology

Volumn 11, Issue 8, 1993, Pages 930-932

  Hamamoto, Hiroshi ^a   Sugiyama, Yoshlnori ^a   Nakagawa, Noriaki ^a   Hashida, Eiji ^a   Matsunaga, Yuji ^a   Takemoto, Shlzume ^a   Watanabe, Yuichlro ^a,b   Okada, Vbshimi ^b  

^a KANEBO LTD   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; VIRUS VECTOR;

ARTICLE; DRUG MANUFACTURE; FRUIT; GENE INSERTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATOR GENE; TOBACCO MOSAIC VIRUS; TOMATO; VIRUS PARTICLE;

AMINO ACID SEQUENCE; BASE SEQUENCE; CAPSID; GENETIC VECTORS; IMMUNOBLOTTING; MOLECULAR SEQUENCE DATA; PLANTS, GENETICALLY MODIFIED; PLANTS, TOXIC; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RNA, VIRAL; TEPROTIDE; TOBACCO; TOBACCO MOSAIC VIRUS;

LYCOPERSICON ESCULENTUM; NICOTIANA TABACUM; TOBACCO MOSAIC VIRUS;

EID: 14744286826     PISSN: 0733222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0893-930     Document Type: Article

References (17)

1. Donson, J., Kearney, C. M., Hilf, M. E. and Dawson, W. O. 1991. Systemic expression of a bacterial gene by a tobacco mosaic virus-based vector. Proc. Natl. Acad. Sci. USA 88:7204-7208.
2. Tkkamatsu, N., Ishikawa, M., Meshi, T. and Okada, Y. 1987. Expression of bacterial chloramphenicol acetyltransferase gene in tobacco plants mediated by TMV-RNA. EMBOJ. 6:307-311.
3. Takamatsu, N., Watanabe, Y., Yanagi, H., Meshi, T. et al. 1990. Production of enkephalin in tobacco protoplasts using tobacco mosaic virus RNA vector. FEBS Lett. 209:73-76.
4. Dawson, W. O., Lewandowski, D. J., Hilf, M. E., Bubrick, P. et al. 1989. A tobacco mosaic virus-hybrid expresses and loses an added gene. Virology 172:285-292.
5. Saito, T., Yfcmanaka, K. and Okada, Y. 1990. Long-distance movement of tobacco mosaic virus mutants. Virology 176:329-336.
6. Kmnagai, M. H., Txirpen, T. H., Weinzettl, N., Della-Cioppa, G., et al. 1993. Rapid, high-level expression of biologically active a-trichosanthin in transfected plants by an RNA viral vector. Proc. Natl. Acad. Sci. USA 90:427-430.
7. Skuzeski, J. M., Nichols, L. M., Gesteland, R. F. and Atkins, F. 1991. The signal for a leaky UAG codon in several plant viruses includes the two downstream codons. J. Mol. Biol. 218:365-373.
8. Karaki, H., Doi, K., Sugano, S., Uchiwa, H. et al. 1990. Antihypertensive effect of tryptic hydrolysate of milk casein in spontaneously hypertensive rats. Comp. Biochem. Physiol. 96C:367-371.
9. Meshi, T., Ishikawa, M., Motoyoshi, F., Semba, K. and Okada, Y. 1986. In vitro transcription of infectious RNAs from full-length cDNAs of tobacco mosaic virus. Proc. Natl. Acad. Sci. USA 83:5043-5047.
10. Meshi, T., Watanabe, Y. and Okada, Y. 1992. Molecular pathology of tobacco mosaic virus revealed by biologically active cDNAs, p. 149-186. in: Genetic Engineering with Plant Viruses. Wilson, T. M. A. and Davis, J. W. (Eds.). CRC Press, Boca Raton. FL.
11. Watanabe, Y., Meshi, T. and Okada, Y. 1987. Infection of tobacco protoplasts with in vitro transcribed tobacco mosaic virus RNA using an improved electroporation method. FEBS Lett. 219:65-69.
12. Mattehews, R. E. F. 1981. Plant Virology. Academic Press, NY.
13. Goelet, P., Lomonossoff, G. P., Butler, P. J. G., Akam, M. E. et al. 1982. Nucleotide sequence of tobacco mosaic virus RNA. Proc. Natl. Acad. Sci. USA 79:5818-5822.
14. Bloomer, A. C., Champness, J. N., Bricogne, G., Staden, R. and Klug, A. 1978. Protein disk of tobacco mosaic virus at 2.8 A resolution showing the interactions within and between subunits. Nature 276:362-368.
15. Sambrook, J., Fritsch, E. F. and Maniatis, T. 1989. Molecular Cloning; A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory, NY.
16. Verver, J., Goldbach, R., Garcia, J. A. and \fos, P. 1987. In vitro expression of a full-length DNA copy of cowpea mosaic virus B RNA: Identification of the BRNA-encoded 24kDa protein as a viral protease. EMBO J. 6:549-554.
17. Otsuki, Y., Tkkebe, I., Ohno, T., Fukuda, M. and Okada, Y. 1977. Reconstitution of tobacco mosaic virus rods occurs bidirectionally from an internal initiation region: Demonstration by electron microscopic serology. Proc. Natl. Acad. Sci. USA 74:1913-1917.