Top-down identification of endogenous peptides up to 9 kDa in cerebrospinal fluid and brain tissue by nanoelectrospray quadrupole time-of-flight tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 40, Issue 2, 2005, Pages 214-226

  Möhnng, Thomas ^a   Kellmann, Markus ^a   Jürgens, Michael ^a   Schrader, Michael ^a,b  

^a BioVisioN AG   (Germany)

^b UNIVERSITY OF APPLIED SCIENCES WEIHENSTEPHAN TRIESDORF   (Germany)

Author keywords

Biomarker; Neuropeptides; Peptidomics; Protein identification; Tandem mass spectrometry

Indexed keywords

BIOMARKERS; BRAIN; DATA REDUCTION; MOLECULAR STRUCTURE; NEUROLOGY; PROTEINS; PURIFICATION; TISSUE;

MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI); MOLECULAR MASS; NANOELECTROSPRAY MEASUREMENTS; TIME-OF FLIGHT MASS SPECTROMETRY (TOFMS);

MASS SPECTROMETRY;

BIOLOGICAL MARKER; NEUROPEPTIDE Y; PEPTIDE FRAGMENT; PROTEIN PRECURSOR; THYMOSIN BETA4; UBIQUITIN;

AMINO ACID SEQUENCE; ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BODY FLUID; BRAIN TISSUE; CEREBROSPINAL FLUID; DEGENERATIVE DISEASE; DISSOCIATION; ENERGY; HUMAN; HUMAN TISSUE; HYPOTHALAMUS; LIQUID CHROMATOGRAPHY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PEPTIDOMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; QUADRUPOLE MASS SPECTROMETRY; RAT; SCREENING; SIGNAL PROCESSING; TIME OF FLIGHT MASS SPECTROMETRY; VALIDATION PROCESS;

AMINO ACID SEQUENCE; ANIMALS; BRAIN CHEMISTRY; CEREBROSPINAL FLUID; CHROMATOGRAPHY, LIQUID; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NANOTECHNOLOGY; NEUROPEPTIDE Y; NEUROPEPTIDES; PEPTIDE MAPPING; PROTEIN ARRAY ANALYSIS; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THYMOSIN; UBIQUITIN;

EID: 14744276328     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.741     Document Type: Article

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