Metalloproteinase-collagenase inhibitor examples

Enzymes and their Inhibitors: Drug Development

Volumn , Issue , 2004, Pages 292-300

  Supuran, Claudiu T ^a   Scozzafava, Andrea ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

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[No Author keywords available]

Indexed keywords

EID: 14644445333     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (12)

1. Barrett, A.J., Rawlings, N.D., and Woessner, J.F., Eds. (1998). Handbook of Proteolytic Enzymes. London: Academic Press (CD-ROM), and references cited therein.
2. Smith, H.J. and Simons, C., Eds. (2002). Proteinase and Peptidase Inhibition -Recent Potential Targets for Drug Development. London: Taylor & Francis.
3. Berger, A. and Schechter, I. (1970). Mapping the active site of papain with the aid of peptide substrates and inhibitors. Philosophical Transactions of the Royal Society of London, 257, 249-264.
4. Whittaker, M., Floyd, C.D., Brown, P., and Gearing, A.J.H. (1999). Design and therapeutic application of matrix metalloproteinase inhibitors. Chemical Reviews, 99, 2735-2776.
5. Supuran, C.T. and Scozzafava, A. (2002). Matrix metalloproteinsases (MMPs), in Proteinase and Peptidase Inhibition - Recent Potential Targets for Drug Development. Smith, H.J. and Simons, C., Eds., 35-61. London: Taylor & Francis.
6. Nagase, H. and Woessner, J.F. Jr. (1999). Matrix metalloproteinases. Journal of Biological Chemistry, 274, 21491-21494.
7. Grams, F., Crimmin, M., Hinnes, L., Huxley, P., Pieper, M., Tschesche, H., and Bode, W. (1995). Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor. Biochemistry, 34, 14012-14020.
8. Lovejoy, B., Hassell, A.M., Luther, M.A., Weigl, D., and Jordan, S.R. (1994). Crystal structures of recombinant 19-kDa human fibroblast collagenase complexed to itself. Biochemistry, 33, 8207-8217.
9. Supuran, C.T., Briganti, F., Mincione, G., and Scozzafava, A. (2000). Protease inhibitors:synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of Clostridium histolyticum collagenase. Journal of Enzyme Inhibition, 15, 111-128.
10. Brandstetter, H., Engh, R.A., Graf von Roedern, E., Moroder, L., Huber, R., Bode, W. et al. (1998). Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data. Protein Science, 7, 1303-1309.
11. Scozzafava, A. and Supuran, C.T. (2000a). Protease inhibitors. Part 9. Synthesis of Clostridium histolyticum collagenase inhibitors incorporating sulfonyl-L-alanine hydroxamate moieties. Bioorganic and Medicinal Chemistry Letters, 10, 499-502.
12. Scozzafava, A. and Supuran, C.T. (2000b). Protease inhibitors. Synthesis of potent matrix metalloproteinase and bacterial collagenase inhibitors incorporating N-4-nitrobenzylsulfonyl glycine hydroxamate moieties. Journal of Medicinal Chemistry, 43, 1858-1865.