Overexpression of inducible nitric oxide synthase in the kidney of the spontaneously hypertensive rat

Clinical and Experimental Hypertension

Volumn 27, Issue 1, 2005, Pages 17-31

  Kumar, Ujendra ^a   Chen, Jun ^b   Sapoznikhov, Valeriy ^b   Canteros, Griselda ^b   White, Beatrix H ^b   Sidhu, Anita ^b  

^a ROYAL VICTORIA HOSPITAL   (Canada)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Catalase; Free radicals; Glutathione peroxidase; Hypertension; Nitric oxide; Superoxide dismutase

Indexed keywords

3 NITROTYROSINE; CATALASE; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; SODIUM;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIURESIS; ENZYME ACTIVITY; GENE OVEREXPRESSION; KIDNEY; KIDNEY BLOOD FLOW; KIDNEY CORTEX; KIDNEY INJURY; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; MALE; NITRATIVE DAMAGE; NONHUMAN; OXIDATIVE STRESS; PROMOTER REGION; PROTEIN MODIFICATION; RAT; RAT STRAIN; REGULATORY MECHANISM; SODIUM EXCRETION; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; ANTIOXIDANTS; HYPERTENSION, RENAL; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULES, PROXIMAL; MALE; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; TYROSINE;

EID: 14644445184     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.1081/CEH-200044249     Document Type: Article

References (49)

1. Landmesser U, Harrison DG. Oxidative stress and vascular damage in hypertension. Coron Artery Dis 2001; 12(6):455-461.
2. Zalba G, San Jose G, Moreno MU, Fortune MA, Fortune A, Beaumont FJ, Diez J. Oxidative stress in arterial hypertension: role of NAD(P)H oxidase. Hypertension 2001; 38(6):1395-1399.
3. Hamilton C. Nitric oxide, oxidative stress and hypertension: a complex equation. J Hypertens 2002; 20(6):1055-1056.
4. Leclercq B, Jaimes EA, Raij L. Nitric oxide synthase and hypertension. Curr Opin Nephrol Hypertens 2002; 11(2):185-189.
5. Reckelhoff JF, Romero JC. Role of oxidative stress in angiotensin-induced hypertension. Am J Physiol Regul Integr Comp Physiol 2003; 284(4):R893-R912.
6. Rikans LE, Hornbrook KR. Lipid peroxidation, antioxidant protection and aging. Biochim Biophys Acta 1997; 1362(2-3):116-127.
7. Stamler JS. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 1994; 78(6):931-936.
8. Chou TC, Yen MH, Li CY, Ding YA. Alterations of nitric oxide synthase expression with aging and hypertension in rats. Hypertension 1998; 31(2):643-648.
9. Nava E, Llinas MT, Gonzalez JD, Salazar FJ. Nitric oxide synthase activity in renal cortex and medulla of normotensive and spontaneously hypertensive rats. Am J Hypertens 1996; 9(12 Pt 1):1236-1239.
10. Ischiropoulos H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys 1998; 356(1):1-11.
11. Virag L, Szabo E, Gergely P, Szabo C. Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention. Toxicol Lett 2003; 140-141:113-124.
12. Herce-Pagliai C, Kotecha S, Shuker DE. Analytical methods for 3-nitrotyrosine as a marker of exposure to reactive nitrogen species: a review. Nitric Oxide 1998; 2(5):324-336.
13. Salvemini D, Cuzzocrea S. Superoxide, superoxide dismutase and ischemic injury. Curr Opin Investig Drugs 2002; 3(6):886-895.
14. Alderton WK, Cooper CE, Knowles RG. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001; 357(Pt 3):593-615.
15. Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem 1994; 63:175-195.
16. Busse R, Fleming I, Hecker M. Signal transduction in endothelium- dependent vasodilatation. Eur Heart J 1993; 14(suppl I):2-9.
17. Ruan J, Xie Q, Hutchinson N, Cho H, Wolfe GC, Nathan C. Inducible nitric oxide synthase requires both the canonical calmodulin-binding domain and additional sequences in order to bind calmodulin and produce nitric oxide in the absence of free Ca2+. J Biol Chem 1996; 271(37):22679-22686.
18. Solzbach U, Hornig B, Jeserich M, Just H. Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation 1997; 96(5):1513-1519.
19. Kumar U, Shin Y, Wersinger C, Patel Y, Sidhu A. Diminished expression of constitutive nitric oxide synthases in the kidney of spontaneously hypertensive rat. Clin Exp Hypertens 2003; 25(4):271-282.
20. Romero-Alvira D, Roche E. High blood pressure, oxygen radicals and antioxidants: etiological relationships. Med Hypotheses 1996; 46(4):414-420.
21. White BH, Sidhu A. Increased oxidative stress in renal proximal tubules of the spontaneously hypertensive rat: a mechanism for defective dopamine D1A receptor/G-protein coupling. J Hypertens 1998; 16(11):1659-1665.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-254.
23. Whanger PD, Weswig PH, Schmitz JA, Oldfield JE. Effects of selenium and vitamin E on blood selenium levels, tissue glutathione peroxidase activities and white muscle disease in sheep fed purified or hay diets. J Nutr 1977; 107(7):1298-1307.
24. Salazar FJ, Alberola A, Pinilla JM, Romero JC, Quesada T. Salt-induced increase in arterial pressure during nitric oxide synthesis inhibition. Hypertension 1993; 22(1):49-55.
25. Cowley AW Jr, Mattson DL, Lu S, Roman RJ. The renal medulla and hypertension. Hypertension 1995; 25(4 Pt 2):663-673.
26. Welch WJ, Wilcox CS, Thomson SC. Nitric oxide and tubuloglomerular feedback. Semin Nephrol 1999; 19(3):251-262.
27. Mattson DL, Bellehumeur TG. Neural nitric oxide synthase in the renal medulla and blood pressure regulation. Hypertension 1996; 28(2):297-303.
28. Kone BC. Nitric oxide in renal health and disease. Am J Kidney Dis 1997; 30(3):311-333.
29. Frohlich ED, Arthus C. Corcoran Memorial Lecture: influence of nitric oxide and angiotensin II on renal involvement in hypertension. Hypertension 1997; 29(1 Pt 2): 188-193.
30. Vidal MJ, Romero JC, Vanhoutte PM. Endothelium-derived relaxing factor inhibits renin release. Eur J Pharmacol 1988; 149(3):401-402.
31. Braam B. Renal endothelial and macula densa NOS: integrated response to changes in extracellular fluid volume. Am J Physiol 1999; 276(6 Pt 2):R1551-R1561.
32. Wilcox CS, Welch WJ, Murad F, Gross SS, Taylor G, Levi R, Schmidt HH. Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci U S A 1992; 89(24):11993-11997.
33. Beierwaltes WH. Macula densa stimulation of renin is reversed by selective inhibition of neuronal nitric oxide synthase. Am J Physiol 1997; 272(5 Pt 2):R1359-R1364.
34. Wang X, Lu M, Gao Y, Papapetropoulos A, Sessa WC, Wang W. Neuronal nitric oxide synthase is expressed in principal cell of collecting duct. Am J Physiol 1998; 275(3 Pt 2):F395-F399.
35. Giebisch G, Wang W. Potassium transport: from clearance to channels and pumps. Kidney Int 1996; 49(6):1624-1631.
36. Stoos BA, Garcia NH, Garvin JL. Nitric oxide inhibits sodium reabsorption in the isolated perfused cortical collecting duct. J Am Soc Nephrol 1995; 6(1):89-94.
37. Wilcox CS. Role of macula densa NOS in tubuloglomerular feedback. Curr Opin Nephrol Hypertens 1998; 7(4):443-449.
38. Welch WJ, Tojo A, Lee JU, Kang DG, Schnackenberg CG, Wilcox CS. Nitric oxide synthase in the JGA of the SHR: expression and role in tubuloglomerular feedback. Am J Physiol 1999; 277(1 Pt 2):F130-F138.
39. Cuevas P, Garcia-Calvo M, Carceller F, Reimers D, Zazo M, Cuevas B, Munoz-Willery I, Martinez-Coso V, Lamas S, Gimenez-Gallego G. Correction of hypertension by normalization of endothelial levels of fibroblast growth factor and nitric oxide synthase in spontaneously hypertensive rats. Proc Natl Acad Sci U S A 1996; 93(21):11996-12001.
40. Nava E, Noll G, Luscher TF. Nitric oxide in cardiovascular diseases. Ann Med 1995; 27(3):343-351.
41. Persson AE, Gutierrez A, Pittner J, Ring A, Ollerstam A, Brown R, Liu R, Thorup C. Renal NO production and the development of hypertension. Acta Physiol Scand 2000; 168(1):169-174.
42. Vaziri ND, Ni Z, Oveisi F, Liang K, Pandian R. Enhanced nitric oxide inactivation and protein nitration by reactive oxygen species in renal insufficiency. Hypertension 2002; 39(1):135-141.
43. Vaziri ND, Ding Y, Ni Z. Nitric oxide synthase expression in the course of lead-induced hypertension. Hypertension 1999; 34:558-562.
44. Jenner P, Olanow CW. Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 1996; 47(6 suppl 3):S161-S170.
45. Avissar N, Ornt DB, Yagil Y, Horowitz S, Watkins RH, Kerl EA, Takahashi K, Palmer IS, Cohen HJ. Human kidney proximal tubules are the main source of plasma glutathione peroxidase. Am J Physiol 1994; 266(2 Pt 1):C367-C375.
46. Redon J, Oliva MR, Tormos C, Giner V, Chaves J, Iradi A, Saez GT. Antioxidant activities and oxidative stress byproducts in human hypertension. Hypertension 2003; 41(5):1096-1101.
47. Girelli D, Olivieri O, Stanzial AM, Azzini M, Lupo A, Bernich P, Menini C, Gammaro L, Corrocher R. Low platelet glutathione peroxidase activity and serum selenium concentration in patients with chronic renal failure: relations to dialysis treatments, diet and cardiovascular complications. Clin Sci (Lond) 1993; 84(6):611-617.
48. Shou I, Wang LN, Suzuki S, Fukui M, Tomino Y. Effects of antihypertensive drugs on antioxidant enzyme activities and renal function in stroke-prone spontaneously hypertensive rats. Am J Med Sci 1997; 314(6):377-384.
49. Asahi M, Fujii J, Suzuki K, Seo HG, Kuzuya T, Hori M, Tada M, Fujii S, Taniguchi N. Inactivation of glutathione peroxidase by nitric oxide. Implication for cytotoxicity. J Biol Chem 1995; 270(36):21035-21039.