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Volumn 3, Issue 11, 2004, Pages 1352-1354

PPARγ signaling: One size fits all?

Author keywords

Cancer; HER signaling network; Ligands; PPAR signaling

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TRASTUZUMAB; ANTINEOPLASTIC AGENT; LIGAND;

EID: 14644430278     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.3.11.1210     Document Type: Short Survey
Times cited : (5)

References (26)
  • 1
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • Evans RM, Barish GD, Wang YX. PPARs and the complex journey to obesity. Nat Med 2004; 10:355-61.
    • (2004) Nat Med , vol.10 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.X.3
  • 2
    • 0142144332 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARγ) ligands as bifunctional regulators of cell proliferation
    • Na HK, Surh YJ. Peroxisome proliferator-activated receptor gamma (PPARγ) ligands as bifunctional regulators of cell proliferation. Biochem Pharmacol 2003; 66:1381-91.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1381-1391
    • Na, H.K.1    Surh, Y.J.2
  • 4
    • 3042815666 scopus 로고    scopus 로고
    • Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists
    • Grommes C, Landreth GE, Heneka MT. Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists. Lancet Oncol 2004; 5:419-29.
    • (2004) Lancet Oncol , vol.5 , pp. 419-429
    • Grommes, C.1    Landreth, G.E.2    Heneka, M.T.3
  • 7
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
    • Lefebvre AM, Chen I, Desreumaux P, Najib J, Fruchart JC, Geboes K, Briggs M, Heyman R, Auwerx J. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. Nat Med 1998; 4:1053-7.
    • (1998) Nat Med , vol.4 , pp. 1053-1057
    • Lefebvre, A.M.1    Chen, I.2    Desreumaux, P.3    Najib, J.4    Fruchart, J.C.5    Geboes, K.6    Briggs, M.7    Heyman, R.8    Auwerx, J.9
  • 9
    • 0142105505 scopus 로고    scopus 로고
    • Genetic deficiency in PPARγ does not alter development of experimental prostate cancer
    • Saez E, Olson P, Evans RM. Genetic deficiency in PPARγ does not alter development of experimental prostate cancer. Nat Med 2003; 9:1265-6.
    • (2003) Nat Med , vol.9 , pp. 1265-1266
    • Saez, E.1    Olson, P.2    Evans, R.M.3
  • 10
    • 0037458680 scopus 로고    scopus 로고
    • Troglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) ligand, selectively induces the early growth response-1 gene independently of PPARγ. A novel mechanism for its anti-tumorigenic activity
    • Back SJ, Wilson LC, Hsi LC, Eling TE. Troglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) ligand, selectively induces the early growth response-1 gene independently of PPARγ. A novel mechanism for its anti-tumorigenic activity. J Biol Chem 2003; 278:5845-53.
    • (2003) J Biol Chem , vol.278 , pp. 5845-5853
    • Back, S.J.1    Wilson, L.C.2    Hsi, L.C.3    Eling, T.E.4
  • 11
    • 0033537827 scopus 로고    scopus 로고
    • Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorylation of a ligand-independent trans-activating domain
    • Juge-Aubry CE, Hammar E, Siegrist-Kaiser C, Pernin A, Takeshita A, Chin WW, Burger AG, Meier CA. Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorylation of a ligand-independent trans-activating domain. J Biol Chem 1999; 274:10505-10.
    • (1999) J Biol Chem , vol.274 , pp. 10505-10510
    • Juge-Aubry, C.E.1    Hammar, E.2    Siegrist-Kaiser, C.3    Pernin, A.4    Takeshita, A.5    Chin, W.W.6    Burger, A.G.7    Meier, C.A.8
  • 12
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
    • Hu E, Kim JB, Sarraf P, Spiegelman BM. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science 1996; 274:2100-3.
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 13
    • 0032894240 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-γl and negatively regulates its transcriptional activity
    • Camp HS, Tafuri SR, Leff T. c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-γl and negatively regulates its transcriptional activity. Endocrinology 1999; 140:392-7.
    • (1999) Endocrinology , vol.140 , pp. 392-397
    • Camp, H.S.1    Tafuri, S.R.2    Leff, T.3
  • 14
    • 0032588866 scopus 로고    scopus 로고
    • PPARγ activators down-regulate the expression of PPARγ in 3T3-L1 adipocytes
    • Camp HS, Whitton AL, Tafuri SR. PPARγ activators down-regulate the expression of PPARγ in 3T3-L1 adipocytes. FEBS Lett 1999; 447:186-90.
    • (1999) FEBS Lett , vol.447 , pp. 186-190
    • Camp, H.S.1    Whitton, A.L.2    Tafuri, S.R.3
  • 15
    • 0037414826 scopus 로고    scopus 로고
    • Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes
    • Teruel T, Hernandez R, Benito M, Lorenzo M. Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes. J Biol Chem 2003; 278:263-9.
    • (2003) J Biol Chem , vol.278 , pp. 263-269
    • Teruel, T.1    Hernandez, R.2    Benito, M.3    Lorenzo, M.4
  • 16
    • 0030965266 scopus 로고    scopus 로고
    • Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells
    • Rokos CL, Ledwith BJ. Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells. J Biol Chem 1997; 272:13452-7.
    • (1997) J Biol Chem , vol.272 , pp. 13452-13457
    • Rokos, C.L.1    Ledwith, B.J.2
  • 17
    • 0033200395 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway contributes to mitogenic and antiapoptotic effects of peroxisome proliferators in vitro
    • Mounho BJ, Thrall BD. The extracellular signal-regulated kinase pathway contributes to mitogenic and antiapoptotic effects of peroxisome proliferators in vitro. Toxicol Appl Pharmacol 1999; 159:125-33.
    • (1999) Toxicol Appl Pharmacol , vol.159 , pp. 125-133
    • Mounho, B.J.1    Thrall, B.D.2
  • 18
    • 0037119433 scopus 로고    scopus 로고
    • MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species
    • Lennon AM, Ramauge M, Dessouroux A, Pierre M. MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. J Biol Chem 2002; 277:29681-5.
    • (2002) J Biol Chem , vol.277 , pp. 29681-29685
    • Lennon, A.M.1    Ramauge, M.2    Dessouroux, A.3    Pierre, M.4
  • 20
  • 21
    • 0037010076 scopus 로고    scopus 로고
    • Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia
    • Arteaga CL. Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia. Semin Oncol 2002; 29:3-9.
    • (2002) Semin Oncol , vol.29 , pp. 3-9
    • Arteaga, C.L.1
  • 23
    • 0344443788 scopus 로고    scopus 로고
    • Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation
    • Gardner OS, Dewar BJ, Earp HS, Samet JM, Graves LM. Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation. J Biol Chem 2003; 278:46261-9.
    • (2003) J Biol Chem , vol.278 , pp. 46261-46269
    • Gardner, O.S.1    Dewar, B.J.2    Earp, H.S.3    Samet, J.M.4    Graves, L.M.5
  • 24
    • 0042525804 scopus 로고    scopus 로고
    • HER2 regulation of peroxisome proliferator-activated receptor gamma (PPARγ) expression and sensitivity of breast cancer cells to PPARγ ligand therapy
    • Yang Z, Bagheri-Yarmand R, Balasenthil S, Hortobagyi G, Sahin AA, Bames CJ, Kumar R. HER2 regulation of peroxisome proliferator-activated receptor gamma (PPARγ) expression and sensitivity of breast cancer cells to PPARγ ligand therapy. Clin Cancer Res 2003; 9:3198-203.
    • (2003) Clin Cancer Res , vol.9 , pp. 3198-3203
    • Yang, Z.1    Bagheri-Yarmand, R.2    Balasenthil, S.3    Hortobagyi, G.4    Sahin, A.A.5    Bames, C.J.6    Kumar, R.7
  • 25
    • 0035199286 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells
    • Pignatelli M, Cortes-Canteli M, Lai C, Santos A, Perez-Castillo A. The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells. J Cell Sci 2001; 114:4117-26.
    • (2001) J Cell Sci , vol.114 , pp. 4117-4126
    • Pignatelli, M.1    Cortes-Canteli, M.2    Lai, C.3    Santos, A.4    Perez-Castillo, A.5
  • 26
    • 2942602908 scopus 로고    scopus 로고
    • Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells
    • Siavash H, Nikitakis NG, Sauk JJ. Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells. Cancer Lett 2004; 211:97-103.
    • (2004) Cancer Lett , vol.211 , pp. 97-103
    • Siavash, H.1    Nikitakis, N.G.2    Sauk, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.