Corticosteroid avoidance in pediatric renal transplantation

Pediatric Nephrology

Volumn 20, Issue 3 SPEC. ISS., 2005, Pages 418-426

  Vidhun, Jayakumar R ^a   Sarwal, Minnie M ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Avoidance; Corticosteroid; Daclizumab; Growth; Pediatric; Renal transplant

Indexed keywords

ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; CALCINEURIN INHIBITOR; CORTICOSTEROID; CYCLOSPORIN; CYCLOSPORIN A; DACLIZUMAB; DOPAMINE; DRUG METABOLITE; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH HORMONE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2 RECEPTOR ANTIBODY; LIPID; MANNITOL; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISOLONE; RAPAMYCIN; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY;

ACNE; ACUTE GRAFT REJECTION; AGE; AREA UNDER THE CURVE; ARTHROPATHY; AVASCULAR NECROSIS; BONE DISEASE; CARDIOVASCULAR DISEASE; CATARACT; CATCH UP GROWTH; CHILD GROWTH; CLINICAL PROTOCOL; CLINICAL TRIAL; COHORT ANALYSIS; CUSHINGOID SYNDROME; DEFORMITY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; DRUG BLOOD LEVEL; DRUG CHOICE; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG SAFETY; DRUG USE; DRUG WITHDRAWAL; FIBROSIS; FOLLOW UP; FRACTURE; GLOMERULOSCLEROSIS; GROWTH RETARDATION; HEART INFARCTION; HUMAN; HYALINE DEGENERATION; HYPERLIPIDEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; INFECTION; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MALIGNANT NEOPLASTIC DISEASE; METABOLIC DISORDER; MORBIDITY; MYOPATHY; NEPHROTOXICITY; ORGAN TRANSPLANTATION; OSTEOPENIA; PATIENT COMPLIANCE; PEDIATRIC SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REVIEW; STROKE; WOUND HEALING IMPAIRMENT;

ADRENAL CORTEX HORMONES; CHILD; CLINICAL TRIALS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION;

EID: 14644429718     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-004-1786-4     Document Type: Review

References (59)

1. Hricik DE, Almawi WY, Strom TB (1994) Trends in the use of glucocorticoids in renal transplantation. Transplantation 57(7):979-989
2. Seikaly M, Ho PL, Emmett L, Tejani A (2001) The 12th Annual Report of the North American Pediatric Renal Transplant Cooperative Study: Renal transplantation from 1987 through 1998. Pediatr Transplant 5(3):215-231 10.1046/j.1397-3142.2001.00001.x
3. NAPRTCS (2002) 2002 Annual report. North American Pediatric Renal Transplant Cooperative Study, Boston, MA
4. Ettenger RB (1992) Age and the immune response in pediatric renal transplantation. Eur J Pediatr 151(Suppl 1):S7-S8
5. Evans EER (1994) Immune response in pediatric renal transplantation. Wiley-Liss, New York
6. Schroeder TJR, Ryckman FC, Hurtubise PE et al. (1991) Immunological monitoring during and following OKT3 therapy in children. Clin Transplant 5:191-196
7. Sarwal MM, Cecka JM, Millan MT, Salvatierra O, Jr. (2000). Adult-size kidneys without acute tubular necrosis provide exceedingly superior long-term graft outcomes for infants and small children: A single center and UNOS analysis. United Network for Organ Sharing. Transplantation 70(12):1728-1736
8. Gjertson DW, Cecka JM (2001) Determinants of long-term survival of pediatric kidney grafts reported to the United Network for Organ Sharing kidney transplant registry. Pediatr Transplant 5(1):5-15
9. Hochberg Z (2002) Mechanisms of steroid impairment of growth. Horm Res 58(Suppl 1):33-38 10.1159/000064764
10. Fryer JP, Benedetti E, Gillingham K, Najarian JS, Matas AJ (1994) Steroid-related complications in pediatric kidney transplant recipients in the cyclosporine era. Transplant P 26(1):91-92
11. Ettenger R (2001) The practical problems of prednisone in pediatric renal transplantation. Transplant P 33(1-2):989-991
12. Veenstra DL, Best JH, Hornberger J, Sullivan SD, Hricik DE (1999) Incidence and long-term cost of steroid-related side effects after renal transplantation. Am J Kidney Dis 33(5):829-839 1:STN:280:DyaK1M3jtVWmsw%3D%3D
13. Tejani A, Butt KM, Rajpoot D, Gonzalez R, Buyan N, Pomrantz A et al. (1989) Strategies for optimizing growth in children with kidney transplants. Transplantation 47(2):229-233 1:STN:280:BiaC2cnosFA%3D
14. Guest G, Berard E, Crosnier H, Chevallier T, Rappaport R, Broyer M (1998) Effects of growth hormone in short children after renal transplantation. French Society of Pediatric Nephrology. Pediatr Nephrol 12(6):437-446
15. Hokken-Koelega AC, Stijnen T, de Jong RC, Donckerwolcke RA, Groothoff JW, Wolff ED et al. (1996) A placebo-controlled, double-blind trial of growth hormone treatment in prepubertal children after renal transplant. Kidney Int Suppl 53:S128-S134
16. Maxwell H, Rees L (1998) Randomised controlled trial of recombinant human growth hormone in prepubertal and pubertal renal transplant recipients. British Association for Pediatric Nephrology. Arch Dis Child 79(6):481-487
17. Fine RN, Stablein D, Cohen AH, Tejani A, Kohaut E (2002) Recombinant human growth hormone post-renal transplantation in children: A randomized controlled study of the NAPRTCS. Kidney Int 62(2):688-696 10.1046/j.1523-1755.2002.00489.x
18. Buckels JA, Barnes AD (1982) Low-dose steroid regimens after renal transplantation. Lancet 1(8283):1250 10.1016/S0140-6736(82)92376-5
19. Broyer M, Guest G, Gagnadoux MF (1992) Growth rate in children receiving alternate-day corticosteroid treatment after kidney transplantation. J Pediatr 120(5):721-725
20. Feldhoff C, Goldman AI, Najarian JS, Mauer SM (1984) A comparison of alternate day and daily steroid therapy in children following renal transplantation. Int J Pediatr Nephrol 5(1):11-14 10.1016/ S0140-6736(82)92376-5
21. Jabs K, Sullivan EK, Avner ED, Harmon WE (1996) Alternate-day steroid dosing improves growth without adversely affecting graft survival or long-term graft function. A report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation 61(1):31-36
22. Ponticelli C, Tarantino A, Montagnino G (2001) Steroid withdrawal in renal transplant recipients. Transplant P 33(1-2):987-988
23. Basadonna GP, Matas AJ, Gillingham KJ, Payne WD, Dunn DL, Sutherland DE et al. (1993) Relationship between early vs late acute rejection and onset of chronic rejection in kidney transplantation. Transplant P 25(1 Pt 2):910-911
24. Basadonna GP, Matas AJ, Gillingham KJ, Payne WD, Dunn DL, Sutherland DE et al. (1993) Early versus late acute renal allograft rejection: Impact on chronic rejection. Transplantation 55(5):993-995 1:STN:280:ByyB28bivF0%3D
25. Hricik DE, Schulak JA (1993) Metabolic effects of steroid withdrawal in adult renal transplant recipients. Kidney Int Suppl 43:S26-S29
26. Hricik DE, Whalen CC, Lautman J, Bartucci MR, Moir EJ, Mayes JT et al. (1992) Withdrawal of steroids after renal transplantation - clinical predictors of outcome. Transplantation 53(1):41-45 1:STN:280:By2C38vls1c%3D
27. Sarwal MM, Vidhun JR, Alexander SR, Satterwhite T, Millan M, Salvatierra O Jr (2003) Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation. Transplantation 76(9):1331-1339 10.1097/01.TP.0000092950.54184.67
28. Solez K, Vincenti F, Filo RS (1998) Histopathologic findings from 2-year protocol biopsies from a U.S. multicenter kidney transplant trial comparing tarolimus versus cyclosporine: A report of the FK506 Kidney Transplant Study Group. Transplantation 66(12):1736-1740
29. Rush D, Nickerson P, Gough J, McKenna R, Grimm P, Cheang M et al. (1998) Beneficial effects of treatment of early subclinical rejection: A randomized study. J Am Soc Nephrol 9(11):2129-2134
30. Birkeland SA (1996) Steroid-free immunosuppression in renal transplantation. Lancet 348(9034):1105-1106
31. Birkeland SA (2001) Steroid-free immunosuppression in renal transplantation: A long-term follow-up of 100 consecutive patients. Transplantation 71(8):1089-1090
32. Birkeland SA, Larsen KE, Rohr N (1998) Pediatric renal transplantation without steroids. Pediatr Nephrol 12(2):87-92
33. Cole E, Landsberg D, Russell D, Zaltzman J, Kiberd B, Caravaggio C et al. (2001) A pilot study of steroid-free immunosuppression in the prevention of acute rejection in renal allograft recipients. Transplantation 72(5):845-850 10.1097/00007890-200109150-00018
34. Sarwal MM, Yorgin PD, Alexander S, Millan MT, Belson A, Belanger N et al. (2001) Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation. Transplantation 72(1):13-21
35. Nussenblatt RB, Fortin E, Schiffman R, Rizzo L, Smith J, Van Veldhuisen P et al. (1999) Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: A phase I/II clinical trial. P Natl Acad Sci USA 96(13):7462-7466 10.1073/pnas.96.13.7462
36. Sarwal MVJ, Ho M, Salvatierra O (2003) Single center and NAPRTCS analysis confirm unprecedented growth patterns in steroid-free immunosuppression. Am J Transplant 3(Suppl 5):166
37. Stock PG, Lantz M, Light S, Vincenti F (1996) In vivo (phase I) trial and in vitro efficacy of humanized anti-Tac for the prevention of rejection in renal transplant recipients. Transplant P 28(2):915-916
38. Cattaneo D, Perico N, Gaspari F, Gotti E, Remuzzi G (2002) Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation. Kidney Int 62(3):1060-1067 10.1046/ j.1523-1755.2002.00531.x
39. Chao SM, Jones CL, Powell HR, Johnstone L, Francis DM, Becker GJ et al. (1994) Triple immunosuppression with subsequent prednisolone withdrawal: 6 years' experience in paediatric renal allograft recipients. Pediatr Nephrol 8(1):62-69
40. Ingulli E, Sharma V, Singh A, Suthanthiran M, Tejani A (1993) Steroid withdrawal, rejection and the mixed lymphocyte reaction in children after renal transplantation. Kidney Int Suppl 43:S36-S39
41. Ingulli E, Tejani A, Markell M (1993) The beneficial effects of steroid withdrawal on blood pressure and lipid profile in children posttransplantation in the cyclosporine era. Transplantation 55(5):1029-1033
42. Roberti I, Reisman L, Lieberman KV, Burrows L (1994) Risk of steroid withdrawal in pediatric renal allograft recipients (a 5-year follow-up). Clin Transplant 8(4):405-408
43. Reisman L, Lieberman KV, Burrows L, Schanzer H (1990) Follow-up of cyclosporine-treated pediatric renal allograft recipients after cessation of prednisone. Transplantation 49(1):76-80
44. Motoyama O, Hasegawa A, Ohara T, Hattori M, Kawaguchi H, Takahashi K et al. (1997) A prospective trial of steroid cessation after renal transplantation in pediatric patients treated with cyclosporine and mizoribine. Pediatr Transplant 1(1):29-36
45. Ellis D (2000) Growth and renal function after steroid-free tacrolimus-based immunosuppression in children with renal transplants. Pediatr Nephrol 14(7):689-694
46. Ratcliffe PJ, Dudley CR, Higgins RM, Firth JD, Smith B, Morris PJ (1996) Randomised controlled trial of steroid withdrawal in renal transplant recipients receiving triple immunosuppression. Lancet 348(9028):643-648 10.1016/S0140-6736(96)02510-X
47. Shapiro R, Jordan ML, Scantlebury VP, Vivas C, Gritsch HA, McCauley J et al. (1998) Outcome after steroid withdrawal in renal transplant patients receiving tacrolimus-based immunosuppression. Transplant P 30(4):1375-1377 10.1016/S0041-1345(98)00280-2
48. Maiorca R, Cristinelli L, Brunori G, Setti G, Salerni B, De Nobili U et al. (1988) Prospective controlled trial of steroid withdrawal after six months in renal transplant patients treated with cyclosporine. Transplant P 20(3 Suppl 3):121-125 1:STN:280:BieB28rjtFQ%3D
49. Mahalati K, Kahan BD (2001) A pilot study of steroid withdrawal from kidney transplant recipients on sirolimus-cyclosporine a combination therapy. Transplant P 33(7-8):3232-3233
50. Chakrabarti P, Wong HY, Scantlebury VP, Jordan ML, Vivas C, Ellis D et al. (2000) Outcome after steroid withdrawal in pediatric renal transplant patients receiving tacrolimus-based immunosuppression. Transplantation 70(5):760-764
51. Guyot C, Karam G, Soulillou JP (1994) Pediatric renal transplantation without maintenance steroids. Transplant P 26(1):97
52. Grewal HP, Thistlethwaite JR, Jr., Loss GE, Bruce DS, Siegel CT, Cronin DC et al. (1998) Corticosteroid cessation 1 week following renal transplantation using tacrolimus/mycophenolate mofetil based immunosuppression. Transplant P 30(4):1378-1379 10.1016/ S0041-1345(98)00281-4
53. Nowacka-Cieciura E, Durlik M, Cieciura T, Lewandowska D, Baczkowska T, Kukula K et al. (2002) Steroid withdrawal after renal transplantation - risks and benefits. Transplant P 34(2):560-563
54. Schulak JA, Mayes JT, Moritz CE, Hricik DE (1990) A prospective randomized trial of prednisone versus no prednisone maintenance therapy in cyclosporine-treated and azathioprine-treated renal transplant patients. Transplantation 49(2):327-332
55. Stratta RJ, Armbrust MJ, Oh CS, Pirsch JD, Kalayoglu M, Sollinger HW et al. (1988) Withdrawal of steroid immunosuppression in renal transplant recipients. Transplantation 45(2):323-328
56. Sinclair NR (1992) Low-dose steroid therapy in cyclosporine-treated renal transplant recipients with well-functioning grafts. The Canadian Multicentre Transplant Study Group. Can Med Assoc J 147(5):645-657
57. Pirsch JD, Armbrust MJ, Knechtle SJ, Reed A, D'Alessandro AM, Sollinger HW et al. (1991) Effect of steroid withdrawal on hypertension and cholesterol levels in living related recipients. Transplant P 23(1 Pt 2):1363-1364
58. Vincenti F, Monaco A, Grinyo J, Kinkhabwala M, Roza A (2003) Multicenter randomized prospective trial of steroid withdrawal in renal transplant recipients receiving basiliximab, cyclosporine microemulsion and mycophenolate mofetil. Am J Transplant 3(3):306-311 10.1034/ j.1600-6143.2003.00005.x
59. Matas AJ, Ramcharan T, Paraskevas S, Gillingham KJ, Dunn DL, Gruessner RW et al. (2001) Rapid discontinuation of steroids in living donor kidney transplantation: A pilot study. Am J Transplant 1(3):278-283 10.1034/j.1600-6143.2001.001003278.x