Reduction of intrinsic kinetic and thermodynamic barriers for enzyme-catalysed proton transfers from carbon acid substrates

Journal of Theoretical Biology

Volumn 233, Issue 4, 2005, Pages 563-571

  Bearne, Stephen L ^a   Spiteri, Raymond J ^b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Carbon acids; Enzyme catalysis; Evolution; Marcus formalism; Proton transfers

Indexed keywords

ACID; CARBON;

BIOLOGY; CATALYSIS; ENZYME;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME KINETICS; PRIORITY JOURNAL; PROTON TRANSPORT; THERMODYNAMICS;

EID: 14644429661     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtbi.2004.11.003     Document Type: Article

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