Can dietary supplements of conjugated linoleic acids reduce overweight problems?;Kan konjugerte linolsyrer i CLA-produkter løse overvektsproblemer?

Tidsskrift for den Norske Laegeforening

Volumn 124, Issue 23, 2004, Pages 3051-3054

  Haugen, Margaretha ^a   Alexander, Jan ^a  

^a Division for Miljømedisin   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CONJUGATED LINOLEIC ACID; LIPID;

ADIPOSE TISSUE; AMINO ACID BLOOD LEVEL; BIRTH WEIGHT; CARBOHYDRATE METABOLISM; CLINICAL TRIAL; DIET SUPPLEMENTATION; DIET THERAPY; DRUG SAFETY; HUMAN; HYPERLIPIDEMIA; INSULIN RESISTANCE; LACTATION; LIPID METABOLISM; MILK; MUSCLE TISSUE; NONHUMAN; OBESITY; PUBLICATION; REVIEW; SIDE EFFECT; ANIMAL; BLOOD; CHEMISTRY; DRUG EFFECT; FEMALE; FETUS DEVELOPMENT; PREGNANCY; WEIGHT REDUCTION;

ADIPOSE TISSUE; ANIMALS; DIETARY SUPPLEMENTS; FEMALE; FETAL DEVELOPMENT; HUMANS; INSULIN RESISTANCE; LACTATION; LINOLEIC ACIDS, CONJUGATED; LIPIDS; PREGNANCY; WEIGHT LOSS;

EID: 14644426621     PISSN: 00292001     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Ha YL, Grimm NK, Pariza MW. Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid. Carcinogenesis 1987; 8: 1881-7.
2. Evans M, Brown J, McIntosh M. Isomer-specific effects of conjugated linoleic acid (CLA) on adiposity and lipid metabolism. J Nutr Biochem 2002; 13: 508-16.
3. Herbel BK, McGuire MK, McGuire MA et al. Safflower oil consumption does not increase plasma conjugated linoleic acid concentrations in humans. Am J Clin Nutr 1998; 67: 332-7.
4. Chin S, Liu J, Storkson Y et al. Dietary sources of conjugated dienoic isomers of linoleic acid a newly recognized class of anticarcinogens. J Food Comp Anal 1992; 5: 185-97.
5. Fogerty A, Ford G, Svoronos D. Octadeca-9-11-dienoic acid in foodstuff and in lipids of human blood and breast milk. Nutr Reports Int 1988; 38: 937-44.
6. Gaullier JM, Berven G, Blankson H et al. Clinical trial results support a preference for using CLA preparations enriched with two isomers rather than four isomers in human studies. Lipids 2002; 37: 1019-25.
7. Park Y, Albright KJ, Liu W et al. Effect of conjugated linoleic acid on body composition in mice. Lipids 1997; 32: 853-8.
8. Sisk MB, Hausman DB, Martin RJ et al. Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats. J Nutr 2001; 131: 1668-74.
9. Belury MA. Dietary conjugated linoleic acid in health: physiological effects and mechanisms of action. Annu Rev Nutr 2002; 22: 505-31.
10. Tsuboyama-Kasaoka N, Takahashi M, Tanemura K et al. Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. Diabetes 2000; 49: 1534-42.
11. Brown JM, McIntosh MK. Conjugated linoleic acid in humans: regulation of adiposity and insulin sensitivity. J Nutr 2003; 133: 3041-6.
12. Berven G, Bye A, Hals O et al. Safety of conjugated linoleic acid (CLA) in overweight or obese human volunteers. Eur J Lipid Sci Technol 2000; 102: 455-62.
13. Zambell KL, Keim NL, Van Loan MD et al. Conjugated linoleic acid supplementation in humans: effects on body composition and energy expenditure. Lipids 2000; 35: 777-82.
14. Medina EA, Horn WF, Keim NL et al. Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids 2000; 35: 783-8.
15. Thorn E, Wadstein J, Gudmundsen O. Conjugated linoleic acid reduces body fat in healthy exercising humans. J Int Med Res 2001; 29: 392-6.
16. Mougios V, Matsakas A, Petridou A et al. Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat. J Nutr Biochem 2001; 12: 585-94.
17. Blankson H, Stakkestad JA, Fagertun H et al. Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J Nutr 2000; 130: 2943-8.
18. Smedman A, Vessby B. Conjugated linoleic acid supplementation in humans - metabolic effects. Lipids 2001; 36: 773-81.
19. Gaullier JM, Halse J, Hoye K et al. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am J Clin Nutr 2004; 79: 1118-25.
20. Kamphuis MM, Lejeune MP, Saris WH et al. The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects, Int J Obes Relat Metab Disord 2003; 27: 840-7.
21. Basu S, Riserus U, Turpeinen A et al. Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. Clin Sci 2000; 99: 511-6.
22. Riserus U, Berglund L, Vessby B. Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: a randomised controlled trial, Int J Obes Relat Metab Disord 2001; 25: 1129-35.
23. Zambell KL, Horn WF, Keim NL. Conjugated linoleic acid supplementation in humans: effects on fatty acid and glycerol kinetics. Lipids 2001; 36: 767-72.
24. Benito P, Nelson GJ, Kelley DS et al. The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. Lipids 2001; 36: 229-36.
25. Riserus U, Arner P, Brismar K et al. Treatment with dietary trans 10cis l2 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care 2002; 25: 1516-21.
26. Riserus U, Basu S, Jovinge S et al. Supplementation with conjugated linoleic acid causes isomerdependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation 2002; 106: 1925-9.
27. Masters N, McGuire MA, Beerman KA et al. Maternal supplementation with CLA decreases milk fat in humans. Lipids 2002; 37: 133-8.
28. Noone EJ, Roche HM, Nugent AP et al. The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br J Nutr 2002; 88: 243-51.
29. Kreider RB, Ferreira MP, Greenwood M et al. Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers. J Strength Cond Res 2002; 16: 325-34.
30. Clement L, Poirier H, Niot I et al. Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. J Lipid Res 2002; 43: 1400-9.
31. Stangl GI. High dietary levels of a conjugated linoleic acid mixture alter hepatic glycerophospholipid class profile and cholesterol-carrying serum lipoproteins of rats. J Nutr Biochem 2000; 11: 184-91.
32. Smedman A, Vessby B, Basu S. Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitor. Clin Sci 2004; 106: 67-73.
33. Elias SL, Innis SM. Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. Am J Clin Nutr 2001; 73: 807-14.
34. Perfield JW, Bernal-Santos G, Overton TR et al. Effects of dietary supplementation of rumen-protected conjugated linoleic acid in dairy cows during established lactation. J Dairy Sci 2002; 85: 2609-17.