Zebrafish: A tool to study hemostasis and thrombosis

Current Opinion in Hematology

Volumn 12, Issue 2, 2005, Pages 149-152

  Jagadeeswaran, Pudur ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Coagulation; Hemostasis; Microparticles; Thrombocytes; Thrombosis; Vascular occlusion; Zebrafish

Indexed keywords

PROTHROMBIN;

ANIMAL MODEL; BLOOD VESSEL OCCLUSION; GENETIC MODEL; HEMOSTASIS; KNOCKOUT MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; THROMBOCYTE; THROMBOGENESIS; THROMBOSIS; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; HEMOSTASIS; MODELS, ANIMAL; THROMBOSIS; ZEBRAFISH;

EID: 14644414234     PISSN: 10656251     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.moh.0000155122.27551.6a     Document Type: Review

References (4)

1. Jagadeeswaran P, Gregory M, Day K, et al. Zebrafish: a genetic model for hemostasis and thrombosis. J Thromb Haemost DOI: 10.1111/j.1538-7836. 2004. 00999.x This is the first comprehensive review that describes the introduction of zebrafish as a model to study hemostasis and thrombosis.
2. Jagadeeswaran P, Cykowski M, Thattaliyath B. Vascular occlusion and thrombosis in zebrafish. Methods Cell Biol 2004; 76:489-500. This is the first detailed methodological description of laser-induced vascular occlusion in zebrafish larvae that could be used to screen hemostasis and thrombosis mutants.
3. Day K, Krishnegowda N, Jagadeeswaran P. Knockdown of prothrombin in zebrafish. Blood Cells Mol Dis 2004; 32:191-198. This paper is a detailed investigation of the utility of knockdown technology in the hemostasis area and marks the beginning of such applications in the hemostasis area.
4. Jagadeeswaran P, Cykowski M, Thattaliyath B. Kinetics of thrombocyte and thrombocyte-microparticle recruitment in laser induced arterial thrombus formation in zebrafish [abstract]. Blood 2004; 104;717a. This abstract presents novel concepts in the physiology of thrombus formation in vertebrates.