The infection risk of intrathecal drug infusion pumps after multiple refill procedures

Neuromodulation

Volumn 8, Issue 1, 2005, Pages 36-39

  Dario, Alessandro ^a,b   Scamoni, Carlo ^a,b   Picano, Marco ^a,b   Fortini, Gianpaolo ^a   Cuffari, Salvatore ^a   Tomei, Giustino ^a,b  

^a Azienda Ospedaliero Universitaria   (Italy)

^b UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Baclofen; Infection; Intrathecal infusion; Pump

Indexed keywords

BACLOFEN; MORPHINE;

ADULT; ARTICLE; BACTERIUM CULTURE; CHRONIC PAIN; CLINICAL ARTICLE; COMORBIDITY; DEVICE INFECTION; DRUG DELIVERY SYSTEM; FEMALE; HUMAN; INFECTION RISK; INFUSION PUMP; INTRATHECAL DRUG ADMINISTRATION; MALE; NEUROPATHIC PAIN; OUTPATIENT; PERIODICITY; RECURRENT INFECTION; RESPIRATORY TRACT INFECTION; RISK FACTOR; SPASTICITY; URINARY TRACT INFECTION;

EID: 14644406911     PISSN: 10947159     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1094-7159.2005.05218.x     Document Type: Article

References (22)

1. Penn RD. Intrathecal baclofen for spasticity of spinal origin: seven years of experience. J Neurosurg 1992;77:236-240.
2. Winkelmuller M, Winkelmuller W. Long-term effects of continuous intrathecal opioid treatment in chronic pain of nonmalignant etiology. J Neurosurg 1996;85:458-467.
3. Naumann C, Erdine S, Koulousakis A et al. Drug adverse events and system complications of intrathecal opioid delivery for pain: Origins, detection, manifestations, and management. Neuromodulation 1999;2:92-107.
4. Kumar K, Hunter G, Demeria DD. Treatment of chronic pain by using intrathecal drug therapy compared with conventional pain therapies: a cost-effectiveness analysis. J Neurosurg 2002;97:803-810.
5. Erdine S, Yücel A. Intrathecal morphine delivered by implanted manual pump for cancer pain. Pain Digest 1996;6:161-165.
6. Smith TJ, Staats PS, Deer T et al. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: Impact on pain, drug-related toxicity, and survival. J Clin Oncol 2002;20:4040-4049.
7. Ordia JI, Fischer E, Adamski E et al. Continuous intrathecal baclofen infusion by a programmable pump in 131 consecutive patients with severe spasticity of spinal origin. Neuromodulation 2002;5:16-24.
8. Stempien L, Tsai T. Intrathecal baclofen pump use for spasticity. A clinical survey. Am J Phys Med Rehabil 2000;79:536-541.
9. Vidal J, Fenollosa P, Martin E et al. Safety and efficacy of intrathecal baclofen infusion by implantable pump for thr treatment of severe spinal spasticity: a spanish multicenter study. Neuromodulation 2000;3:175-182.
10. Ochs G, Naumann C, Dimitrijevic M. Intrathecal baclofen therapy for spinal origin spasticity: spinal cord injury, spinal cord disease, and multiple sclerosis. Neuromodulation 1999;2:108-119.
11. Zed PJ, Stiver HG, Devonshire V et al. Continuous intrathecal pump infusion of baclofen with antibiotic drugs for treatment of pump-associated meningitis. Case report. J Neurosurg 2000;92:347-349.
12. Bennett MI, Tai YM, Symonds JM. Staphylococcal meningitis following Synchromed intrathecal pump implant: a case report. Pain 1994;56:243-244.
13. Galloway A, Falope FZ. Pseudomonas aeruginosa infection in an intrathecal baclofen pump: successful treatment with adjunct intra-reservoir gentamicin. Spinal Cord 2000;38:126-128.
14. Samuel M, Finnerty GT, Rudge P. Intrathecal baclofen pump infection treated by adjunct intrareservoir antibiotics instillation. J Neurol Neurosurg Psychiatry 1994;57:1146-1147.
15. Boviatis EJ, Kouyialis AT, Boutsikakis I, Korfias S, Sakas DE. Infected CNS infusion pumps. Is there a chance for treatment without removal? Acta Neurochir 2004;146:463-467.
16. Ranchere JY, Rebattu P, Bobin JY. Bacterial meningitis and intrathecal treatment of chronic pain. Ann Fr Anesth Reanim 1985;4:77-78.
17. Ohlsson LJ, Rydberg TS, Eden T et al. Microbiologic and economic evaluation of multiday infusion pumps for control of cancer pain. Ann Pharmacother 1995;29:972-976.
18. Dahm PO, Nitescu PV, Appelgren LK et al. Efficacy and technical complications of long-term continuous intraspinal infusions of opioid and/or bupivacaine in refractory nonmalignant pain: a comparison between the epidural and the intrathecal approach with externalized or implanted catheters and infusion pumps. Clin J Pain 1998;14:4-16.
19. Muller H, Biscoping J, Gips H et al. Hygienic relations and stability of drugs in peridural long-term infusion with implanted or external pumps. Anaesthesist 1985;34:247-251.
20. Cook TM, James PA, Stannard CF. Diamorphine and bupivacaine mixtures: an in vitro study of microbiological safety. Pain 1998;76:259-263.
21. Nitescu P, Hultman E, Appelgren L et al. Bacteriology, drug stability and exchange of percutaneous delivery systems and antibacterial filters in long-term intrathecal infusion of opioid drugs and bupivacaine in "refractory" pain. Clin J Pain 1992;8:324-337.
22. Van Wijngaerden E, Peetermans WE, Vandersmissen J et al. Foreign body infection: a new rat model for prophylaxis and treatment. J Antimicrob Chemother 1999;44:669-674.