Probing the interactions between the folding elements early in the folding of Escherichia coli dihydrofolate reductase by systematic sequence perturbation analysis

Journal of Molecular Biology

Volumn 347, Issue 2, 2005, Pages 337-353

  Arai, Munehito ^a   Iwakura, Masahiro ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Dihydrofolate reductase; Foldability; Folding elements; Protein folding; Systematic sequence perturbation analysis

Indexed keywords

AMINO ACID; ASPARAGINE; BACTERIAL ENZYME; DIHYDROFOLATE REDUCTASE; ISOLEUCINE; TRYPTOPHAN; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; ESCHERICHIA COLI; FLUORESCENCE; HYDROPHOBICITY; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

EID: 14644405526     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.01.033     Document Type: Article

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