Asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate with two co-existing, recombinant Escherichia coli strains

Biotechnology Letters

Volumn 27, Issue 2, 2005, Pages 119-125

  Liu, Ying ^a   Xu, Zhinan ^a   Jing, Keju ^a   Jiang, Xiaoxia ^a   Lin, Jianping ^a   Wang, Fang ^a   Cen, Peilin ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Aldehyde reductase; Asymmetric reduction; Ethyl (R) 4 chloro 3 hydroxybutanoate; Glucose dehydrogenase; NADPH regeneration

Indexed keywords

ALDEHYDES; CATALYSTS; ENZYME KINETICS; GENES; GLUCOSE; PURIFICATION;

ASYMMETRIC REDUCTION; BIOTRANSFORMATION; OPTICAL PURITY; RECOMBINANT STRAINS;

ESCHERICHIA COLI;

ACETOACETIC ACID DERIVATIVE; ALDEHYDE REDUCTASE; BUTYRIC ACID DERIVATIVE; ETHYL 4 CHLORO 3 HYDROXYBUTANOATE; ETHYL 4 CHLORO 3 OXOBUTANOATE; ETHYL 4-CHLORO-3-HYDROXYBUTANOATE; ETHYL 4-CHLORO-3-OXOBUTANOATE; GLUCOSE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RECOMBINANT PROTEIN;

ARTICLE; CHEMISTRY; ESCHERICHIA COLI; GENETICS; METABOLISM; METHODOLOGY; MICROBIOLOGY; OXIDATION REDUCTION REACTION;

ACETOACETATES; ALDEHYDE REDUCTASE; BUTYRIC ACIDS; ESCHERICHIA COLI; GLUCOSE DEHYDROGENASES; INDUSTRIAL MICROBIOLOGY; NADP; OXIDATION-REDUCTION; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 14644393049     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10529-004-7336-0     Document Type: Article

References (10)

1. Itamar W, Daniel M (1989) Enzyme-catalysed biotransirmations through photochemical regeneration of nicotinamide cofactors. Enzyme Microb. Technol. 11: 467-483.
2. Kataoka M, Rohani LPS, Yamamoto K, Wada M, Kawabata H, Kita K, Yanase H, Shimizu S (1997) Enzymatic production of ethyl (R)-4-chloro-3-hydroxybutanoate: asymmetric reduction of ethyl 4-chloro-3-oxobutanoate by an Escherichia coli reanstormant expressing the aldehyde reductase gene from yeast. Appl. Microbiol. Biotechnol. 48: 699-703.
3. Kataoka M, Yamamoto K, Kawabata H, Wada M, Kita K, Yanase H, Shimizu S (1999) Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes. Appl. Microbiol. Biotechol. 51: 486-490.
4. Kita K, Kataoka M, Shimizu S (1999) Diversity of 4-chloroacetoacetate ethyl ester-reducing enzymes in yeasts and their application to chiral alcohol synthesis. J. Biosci. Bioeng. 88: 591-598.
5. Langer RS, Hamilton BK, Gardner CR, Archer MC, Colton CK (1976) Enzymatic regeneration of ATP. Am. Inst. Chem. Eng. J. 22: 1079-1085.
6. Lixin S, Dongzhi W, Siliang Z, Erli W (2001) Studies on synthesis of glutathione by E. coli Bl21 (pTrc-gsh) coupled with Saccharomyces cerevisiae. Chinese J. Biotechnol. 17: 452-455.
7. Marino JP, McClure MS, Holub DP, Comasseto JV, Tucci FC (2002) Stereocontrolled synthesis of (-)-macrolactin A. J. Am. Chem. Soc. 124: 1664-1668.
8. Shimizu S, Kataoka M, Morishita A, Katah M, Morikawa T, Miyoshi T, Yamada H (1990) Microbial asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to optically active (R)-4-chloro-3-hydroxybutanoate. Biotechnol Lett. 12: 593-596.
9. Song CE, Lee JK, Lee SH, Lee S (1995) New method for the preparation of (R)-carnitine. Tetrahedron: Asymmetry. 5: 1063-1066.
10. Toshihiro N, Toshihide M, Xiaohui W, Seiji N, Tetsuya Y, Itaru U, Hirosuke O (1992) Cloning, nucleotde sequences, and enzymatic properties of glucose dehydrogenase isozymes from Bacillus megaterium IAM1030. J. Bacteriol. 174: 5013-5020.