Systematic delivery of chloroquine and promethazine using pH-sensitive polymers

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 12, Issue 2, 2005, Pages 103-107

  Attama, A A ^a   Ezeamama, U F ^a  

^a UNIVERSITY OF NIGERIA   (Nigeria)

Author keywords

Carbopol 940; Chloroquine Phosphate; Eudragits; Preferential Release; Promethazine Hydrochloride

Indexed keywords

CARBOPOL 940; CARBOXYMETHYLCELLULOSE; CHLOROQUINE; EUDRAGIT; PROMETHAZINE;

ARTICLE; DENSITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; FLOW RATE; INTESTINE FLUID; PH; PRIORITY JOURNAL; STOMACH JUICE;

CHLOROQUINE; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; POLYMERS; POLYMETHACRYLIC ACIDS; PROMETHAZINE;

EID: 14644389510     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/10717540590921423     Document Type: Article

References (9)

1. Ashord, M., Fell, J., Allwood, D., Sharms, H., and Woodhead, D. 1993. An evaluation of pectin as a carrier for drug targeting to the colon. J. Control. Rel. 26:213-220.
2. Chacko, A., Szaz, K. F., Howard J., and Cummings, J. H. 1990. Non-invasive method for delivery of traces, subs or small quantities of other materials to the colon. J. Control. Rel. 31:106-110.
3. Dew, M. J., Hughes, P. J., Lee, M. G., Evans, B. K., and Rhodes, J. 1982. An oral preparation to release drugs in the human colon. Br. J. Clin. Pharmacol. 14:405-408.
4. Evans, D. F., Pye, G., Bramley, R., Clark, A. G., Dyson, J. J., and Hard-Castle, J. D. 1988. Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut 29:1035-1041.
5. Milojevic, S., Newton, J. M., Cummings, J. H., Gilson, G. R., Botahm, L. R., Ring, S. G., Stochham, M., and Allwood, M. C. 1994. Amylose as a coating for drug delivery to the colon: preparation and in vitro evaluation using 5-aminosalicylic acid pellets. J. Control. Rel. 38:74-84.
6. Rohm Pharma. 2000. Acrylic polymers for pharmaceutical application, Chemische Fabrick Product Line, Pharma Polymers, Kirschenallee, D-64293 Darmastadt.
7. Saffran, M., Kuman, G. S., Savarian, C., Burnham, J. C., Williams, F., and Neckers, D. C. 1979. A new approach to the oral administration of insulin and other peptide durg. Science 223:1081-1084.
8. Wells, J. J., and Aulton, M. E. 1988. Powder. In Pharmaceutics: The Science of Dosage Form Design. Edinburgh: Churchill Livingstone, 247-248.
9. United States Pharmacopeoia. 1990. United States Pharmacopeoia Convention, Rockville, MD, USA.