Ribosome bypassing at serine codons as a test of the model of selective transfer RNA charging

EMBO Reports

Volumn 6, Issue 2, 2005, Pages 147-150

  Lindsley, Dale ^a   Bonthuis, Paul ^a   Gallant, Jonathan ^a   Tofoleanu, Teodora ^a   Elf, Johan ^b   Ehrenberg, Måns ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Amino acid; Bypassing; Charging; Protein synthesis; tRNA

Indexed keywords

AMINOACYL TRANSFER RNA; BETA GALACTOSIDASE; SERINE; TRANSFER RNA;

AMINO ACID TRANSPORT; ARTICLE; BACTERIUM CULTURE; CODON; CONTROLLED STUDY; ENZYME ASSAY; ENZYME SYNTHESIS; GENETIC CODE; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RIBOSOME;

CODON; ESCHERICHIA COLI K12; GENES, REPORTER; LAC OPERON; RIBOSOMES; RNA, TRANSFER, SER; SERINE;

EID: 14644386964     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400332     Document Type: Article

References (16)

1. Barak Z, Lindsley D, Gallant J (1996) On the mechanism of leftward frameshifting at several hungry codons. J Mol Biol 256: 676-684
2. Elf J, Nilsson D, Tenson T, Ehrenberg M (2003) Selective charging of tRNA isoacceptors explains patterns of codon usage. Science 300: 1718-1722
3. Gallant JA, Lindsley D (1992) Leftward ribosome frameshifting at a hungry codon. J Mol Biol 223: 31-40
4. Gallant JA, Lindsley D (1998) Ribosomes can slide over and beyond 'hungry' codons, resuming protein chain elongation many nucleotides downstream. Proc Natl Acad Sci USA 95: 13771-13776
5. Gallant J, Lindsley D, Masucci JP (2000) The unbearable lightness of peptidyl-tRNA. In The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions, Garrett RA, Douthewaite SR, Liljas A, Matheson AT, Moore PB, Noller HF (eds) pp 385-396. Washington, DC: ASM Press
6. Gallant J, Bonthuis P, Lindsley D (2003) Evidence that the bypassing ribosome travels through the coding gap. Proc Natl Acad Sci USA 100: 13430-13435
7. Gallant J et al (2004) On the role of the starved codon and the takeoff site in ribosome bypassing in Escherichia coli. J Mol Biol 342: 713-724
8. Kaplun A, Chipman DM, Barak Z (2002) Isoleucine starvation caused by sulfometuron methyl in Salmonella typhimurium measured by translational frameshifting. Microbiology 148: 713-717
9. Kurland CG (1992) Translational accuracy and the fitness of bacteria. Annu Rev Genet 26: 29-50
10. Kurland C, Gallant J (1996) Errors of heterologous protein expression. Curr Opin Biotechnol 7: 489-493
11. Lindsley D, Gallant J (1993) On the directional specificity of ribosome frameshifting at a 'hungry' codon. Proc Natl Acad Sci USA 90: 5469-5473
12. Lindsley D, Gallant J, Guarneros G (2003) Ribosome bypassing elicited by tRNA depletion. Mol Microbiol 48: 1267-1274
13. Parker J (1992) Variations in reading the genetic code. In Transfer RNA in Protein Synthesis, Hatfield DL, Lee BJ, Pirtle RM (eds) pp 191-267. Boca Raton, FL: CRC Press
14. Peter K, Lindsley D, Peng L, Gallant JA (1992) Context rules of rightward overlapping reading. New Biol 4: 520-526
15. Pizer LI, Merlie JP (1973) Effect of serine hydroxamate on phospholipid synthesis in Escherichia coli. J Bacteriol 114: 980-987
16. Tosa T, Pizer LI (1971) Effect of serine hydroxamate on the growth of Escherichia coli. J Bacteriol 106: 966-971