Comparative study of oral versus subcutaneous B:9-23 insulin peptide in Balb/c mice as an experimental model for autoimmune diabetes

Annals of the New York Academy of Sciences

Volumn 1029, Issue , 2004, Pages 331-333

  Devendra, Devasenan ^a   Paronen, Johanna ^a   Liu, Edwin ^a   Moriyama, Hiroaki ^a   Taylor, Robert ^a   Miao, Dongmei ^a   Yu, Liping ^a   Eisenbarth, George ^a  

^a UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

Autoantibody; Balb c; Diabetes; Insulin; Poly IC

Indexed keywords

AUTOANTIBODY; INSULIN; INSULIN ANTIBODY; INSULIN B PEPTIDE[9-23]; INSULIN DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; AUTOIMMUNE DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOPATHOGENESIS; INSULITIS; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PANCREAS ISLET CELL; PROTEIN TARGETING; SENSITIZATION;

EID: 14544302107     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1309.038     Document Type: Conference Paper

References (3)

1. ZHANG, Z.J., L. DAVIDSON, G. EISENBARTH & H.L. WEINER. 1991. Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin. Proc. Natl. Acad. Sci. USA 88: 10252-10256.
2. WEGMANN, D.R., M. NORBURY-GLASER & D. DANIEL. 1994. Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice. Eur. J. Immunol. 24: 1853-1857.
3. MORIYAMA, H., L. WEN, N. ABIRU, et al. 2002. Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide. Proc. Natl. Acad. Sci. USA 99: 5539-5544.