Cholesterol detoxification by the nuclear pregnane X receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 8, 2005, Pages 2675-2676

  Kliewer, Steven A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CHOLIC ACID; OXYGENASE; OXYSTEROL; PREGNANE X RECEPTOR; PROGESTERONE; XENOBIOTIC AGENT;

BILE ACID SYNTHESIS; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; DETOXIFICATION; DNA BINDING; LIVER TOXICITY; NONHUMAN; NOTE; PRIORITY JOURNAL; XENOBIOTIC METABOLISM;

ANIMALS; CHOLESTEROL; KIDNEY; LIVER; METABOLIC DETOXICATION, DRUG; MICE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID;

EID: 14544297438     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500159102     Document Type: Note

References (19)

1. Leonarduzzi, G., Sottero, B. & Poli, G. (2002) J. Nutr. Biochem. 13, 700-710.
2. Sonoda, J., Chong, L. W., Downes, M., Barish, G. D., Coulter, S., Liddle, C., Lee, C.-H. & Evans, R. M. (2005) Proc. Natl. Acad. Sci. USA 102, 2198-2203.
3. Xie, W. & Evans, R. M. (2001) J. Biol. Chem. 276, 37739-37742.
4. Kliewer, S. A., Goodwin, B. & Willson, T. M. (2002) Endocr. Rev. 23, 687-702.
5. Dussault, I. & Forman, B. M. (2002) Crit. Rev. Eukaryot. Gene Expr. 12, 53-64.
6. Watkins, R. E., Wisely, G. B., Moore, L. B., Collins, J. L., Lambert, M. H., Williams, S. P., Willson, T. M., Kliewer, S. A. & Redinbo, M. R. (2001) Science 292, 2329-2333.
7. Shenoy, S. D., Spencer, T. A., Mercer-Haines, N. A., Alipour, M., Gargano, M. D., Runge-Morris, M. & Kocarek, T. A. (2004) Drug Metab. Dispos. 32, 66-71.
8. Staudinger, J. L., Goodwin, B., Jones, S. A., Hawkins-Brown, D., MacKenzie, K. I., LaTour, A., Liu, Y., Klaassen, C. D., Brown, K. K., Reinhard, J., et al. (2001) Proc. Natl. Acad. Sci. USA 98, 3369-3374.
9. Xie, W., Radominska-Pandya, A., Shi, Y., Simon, C. M., Nelson, M. C., Ong, E. S., Waxman, D. J. & Evans, R. M. (2001) Proc. Natl Acad. Sci. USA 98, 3375-3380.
10. Kliewer, S. A., Moore, J. T., Wade, L., Staudinger, J. L., Watson, M. A., Jones, S. A., McKee, D. D., Oliver, B. B., Willson, T. M., Zetterstrom, R. H., et al. (1998) Cell 92, 73-82.
11. Shenoy, S. D., Spencer, T. A., Mercer-Haines, N. A., Abdolalipour, M., Wurster, W. L., Runge-Morris, M. & Kocarek, T. A. (2004) Mol. Pharmacol. 65, 1302-1312.
12. Goodwin, B., Gauthier, K. C., Umetani, M., Watson, M. A., Lochansky, M. I., Collins, J. L., Leitersdorf, E., Mangelsdorf, D. J., Kliewer, S. A. & Repa, J. J. (2003) Proc. Natl. Acad. Sci. USA 100, 223-228.
13. Dussault, I., Yoo, H. D., Lin, M., Wang, E., Fan, M., Batta, A. K., Salen, G., Erickson, S. K. & Forman, B. M. (2003) Proc. Natl. Acad. Sci. USA 100, 833-838.
14. Xie, W., Barwick, J. L., Downes, M., Blumberg, B., Simon, C. M., Nelson, M. C., Neuschwander-Tetri, B. A., Brunt, E. M., Guzelian, P. S. & Evans, R. M. (2000) Nature 406, 435-439.
15. Klaassen, C. D. (1969) J. Pharmacol. Exp. Ther. 168, 218-223.
16. Turley, S. D., Spady, D. K. & Dietschy, J. M. (1983) Gastroenterology 84, 253-264.
17. Bodin, K., Andersson, U., Rystedt, E., Ellis, E., Norlin, M., Pikuleva, I., Eggertsen, G., Bjorkhem, I. & Diczfalusy, U. (2002) J. Biol. Chem. 277, 31534-31540.
18. Kullak-Ublick, G. A. & Meier, P. J. (2000) Clin. Liver Dis. 4, 357-385.
19. Bachs, L., Pares, A., Elena, M., Piera, C. & Rodes, J. (1989) Lancet 1, 574-576.