Structure-function relationships of transglutaminases - A contemporary view

Progress in Experimental Tumor Research

Volumn 38, Issue , 2005, Pages 19-36

  Nemes, Zoltán ^a,b   Csosz, Éva ^a   Petrovski, Goran ^a   Fésüs, László ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ISOENZYME; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; GENE EXPRESSION; GENETICS; HUMAN; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVIEW; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; GENE EXPRESSION; HUMANS; ISOENZYMES; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; TRANSGLUTAMINASES;

EID: 14544290552     PISSN: 00796263     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000084231     Document Type: Review

References (44)

1. Robinson NE, Robinson AB: Deamidation of human proteins. Proc Natl Acad Sci USA 2001; 98:12409-12413.
2. Sottrup-Jensen L, Hansen HF, Pedersen HS, Kristensen L: Localization of ε-lysyl-γ-glutamyl cross-links in five human α2-macroglobulin- proteinase complexes. Nature of the high molecular weight cross-linked products. J Biol Chem 1990;265:17727-17737.
3. Hasegawa G, Suwa M, Ichikawa Y, Ohtsuka T, Kumagai S, Kikuchi M, Sato Y, Saito Y: A novel function of tissue-type transglutaminase: Protein disulphide isomerase. Biochem J 2003; 373:793-803.
4. Blaskó B, Mádi A, Fésüs L: Thioredoxin motif of Caenorhabditis elegans PDI-3 provides Cys and His catalytic residues for transglutaminase activity. Biochem Biophys Res Commun 2003; 303:1142-1147.
5. Lorand L: Transglutaminase: Remembering Heinrich Waelsch. Neurochem Int 2002;40:7-12.
6. Folk JE, Finlayson JS: The ε-(-γ-glutamyl)lysine crosslink and the catalytic role of transglutaminases. Adv Protein Chem 1977;31:1-133.
7. Chung SI, Shrager RI, Folk JE: Mechanism of action of guinea pig liver transglutaminase. VII. Chemical and stereochemical aspects of substrate binding and catalysis. J Biol Chem 1970;245: 6424-6435.
8. An G, Meka CS, Bright SP, Veltri RW: Human prostate-specific transglutaminase gene: Promoter cloning, tissue-specific expression, and down-regulation in metastatic prostate cancer. Urology 1999;54:1105-1111.
9. Candi E, Paradisi A, Terrinoni A, Pietroni V, Oddi S, Cadot B, Jogini V, Meiyappan M, Clardy J, Finazzi-Agro A, Melino G: Transglutaminase 5 is regulated by guanine-adenine nucleotides. Biochem J 2004;381:313-319.
10. 2+ and nucleotides. Biochem J 1996;313:803-808.
11. Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM, Rastinejad F: Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium. J Biol Chem 2004;279:7180-7192.
12. Mariniello L, Esposito C, Caputo I, Sorrentino A, Porta R: N-terminus end of rat prostate transglutaminase is responsible for its catalytic activity and GTP binding. Int J Biochem Cell Biol 2003;35:1098-1108.
13. Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM: Roles of calcium ions in the activation and activity of the transglutaminase 3 enzyme. J Biol Chem 2003;278:23834-23841.
14. Nemes Z, Steinert PM: Bricks and mortar of the epidermal barrier. Exp Mol Med 1999;31:5-19.
15. Nemes Z, Marekov LN, Fésüs L, Steinert PM: A novel function for transglutaminase 1: Attachment of long-chain ω-hydroxyceramides to involucrin by ester bond formation. Proc Natl Acad Sci USA 1999;96:8402-8407.
16. Liu S, Cerione RA, Clardy J: Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity. Proc Natl Acad Sci USA 2002; 99:2743-2747.
17. Yee VC, Pedersen LC, Le Trong I, Bishop PD, Stenkamp RE, Teller DC: Three-dimensional structure of a transglutaminase: Human blood coagulation factor XIII. Proc Natl Acad Sci USA 1994;91:7296-7300.
18. Weiss MS, Metzner HJ, Hilgenfeld R: Two non-proline cis peptide bonds may be important for factor XIII function. FEBS Lett 1998;423:291-296.
19. Ahvazi B, Kim HC, Kee SH, Nemes Z, Steinert PM: Three-dimensional structure of the human transglutaminase 3 enzyme: Binding of calcium ions changes structure for activation. EMBO J 2002;21:2055-2067.
20. Ahvazi B, Boeshans KM, Steinert PM: Crystal structure of transglutaminase 3 in complex with GMP: Structural basis for nucleotide specificity. J Biol Chem 2004;279:26716-26725.
21. Noguchi K, Ishikawa K, Yokoyama K, Ohtsuka T, Nio N, Suzuki E: Crystal structure of red sea bream transglutaminase. J Biol Chem 2001;276:12055-12059.
22. Lai TS, Slaughter TF, Koropchak CM, Haroon ZA, Greenberg CS: C-terminal deletion of human tissue transglutaminase enhances magnesium-dependent GTP/ATPase activity. J Biol Chem 1996;271:31191-31195.
23. Murthy SN, Iismaa S, Begg G, Freymann DM, Graham RM, Lorand L: Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity. Proc Natl Acad Sci USA 2002;99:2738-2742.
24. Ahvazi B, Steinert PM: A model for the reaction mechanism of the transglutaminase 3 enzyme. Exp Mol Med 2003;35:228-242.
25. Murthy SN, Wilson JH, Lukas TJ, Veklich Y, Weisel JW, Lorand L: Transglutaminase-catalyzed crosslinking of the Aα and γ constituent chains in fibrinogen. Proc Natl Acad Sci USA 2000;97:44-48.
26. Pedersen LC, Yee VC, Bishop PD, Le Trong I, Teller DC, Stenkamp RE: Transglutaminase factor XIII uses proteinase-like catalytic triad to crosslink macromolecules. Protein Sci 1994;3: 1131-1135.
27. Mariani P, Carsughi F, Spinozzi F, Romanzetti S, Meier G, Casadio R, Bergamini CM: Ligand-induced conformational changes in tissue transglutaminase: Monte Carlo analysis of small-angle scattering data. Biophys J 2000;78:3240-3251.
28. Bergamini CM: GTP modulates calcium binding and cation-induced conformational changes in erythrocyte transglutaminase. FEBS Lett 1988;239:255-258.
29. 43Ca NMR study combined with surface polarity analysis. J Biomol Struct Dyn 2001;19:59-74.
30. Ikura K, Yu C, Nagao M, Sasaki R, Furuyoshi S, Kawabata N: Site-directed mutation in conserved anionic regions of guinea pig liver transglutaminase. Arch Biochem Biophys 1995;318:307-313.
31. Kim HC, Lewis MS, Gorman JJ, Park SC, Girard JE, Folk JE, Chung SI: Protransglutaminase E from guinea pig skin. Isolation and partial characterization. J Biol Chem 1990;265:21971-21978.
32. Balklava Z, Verderio E, Collighan R, Gross S, Adams J, Griffin M: Analysis of tissue transglutaminase function in the migration of Swiss 3T3 fibroblasts: The active-state conformation of the enzyme does not affect cell motility but is important for its secretion. J Biol Chem 2002;277: 16567-16575.
33. Ahvazi B, Boeshans KM, Rastinejad F: The emerging structural understanding of transglutaminase 3. J Struct Biol 2004;147:200-207.
34. h hydrolyzes GTP and ATP. Biochemistry 1997;36:11655-11664.
35. h: A GTP-binding protein with transglutaminase activity and receptor signaling function. Science 1994;264:1593-1596.
36. δ1 and with GTP. Proc Natl Acad Sci USA 1999;96:11815-11819.
37. Feng JF, Readon M, Yadav SP, Im MJ: Calreticulin down-regulates both GTP binding and transglutaminase activities of transglutaminase II. Biochemistry 1999;38:10743-10749.
38. Baek KJ, Das T, Gray CD, Desai S, Hwang KC, Gacchui R, Ludwig M, Im MJ: A 50 KDa protein modulates guanine nucleotide binding of transglutaminase II. Biochemistry 1996;35:2651-2657.
39. 1B-adrenoceptor interacts with multiple sites of transglutaminase II: Characteristics of the interaction in binding and activation. Biochemistry 1999;38:2224-2232.
40. Iismaa SE, Wu MJ, Nanda N, Church WB, Graham RM: GTP binding and signaling by Gh/ transglutaminase II involves distinct residues in a unique GTP-binding pocket. J Biol Chem 2000;275:18259-18265.
41. Lai TS, Hausladen A, Slaughter TF, Eu JP, Stamler JS, Greenberg CS: Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase. Biochemistry 2001;40: 4904-4910.
42. Akimov SS, Krylov D, Fleischman LF, Belkin AM: Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J Cell Biol 2000;148:825-838.
43. Akimov SS, Belkin AM: Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: A role in TGFβ-dependent matrix deposition. J Cell Sci 2001;114:2989-3000.
44. 1 integrin. Exp Cell Res 1999;252:104-113.