Monocytic expression behavior of cytokines in diabetic patients upon inflammatory stimulation

Annals of the New York Academy of Sciences

Volumn 1037, Issue , 2004, Pages 74-78

  Giulietti, Annapaula ^a   Stoffels, Katinka ^a   Decallonne, Brigitte ^a   Overbergh, Lut ^a   Mathieu, Chantal ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Cytokines; Diabetes; IL 12; Monocytes; TNF

Indexed keywords

CD14 ANTIGEN; GLUCOSE; HEMOGLOBIN A1C; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; BODY MASS; CELL DESTRUCTION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; FEMALE; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; TH1 CELL;

EID: 14544285566     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1337.011     Document Type: Conference Paper

References (13)

1. FALCONE, M. & N. SARVETNICK. 1999. Cytokines that regulate autoimmune responses. Curr. Opin. Immunol. 11: 670-676.
2. ROSS, R. 1999. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340: 115-126.
3. GALLEY, H.F. & N.R. WEBSTER. 2004. Physiology of the endothelium. Br. J. Anaesth. 93: 105-113.
4. DANDONA, P., A. ALJADA & A. BANDYOPADHYAY. 2004. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol. 25: 4-7.
5. GIULIETTI, A., L. OVERBERGH, D. VALCKX, et al. 2001. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25: 386-401.
6. HUSSAIN, M.J., M. PEAKMAN, H. GALLATI, et al. 1996. Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Diabetologia 39: 60-69.
7. ADORINI, L. 2001. IL12 and autoimmune diabetes. Nat. Genet. 27: 131-132.
8. ALLEVA, D.G., R.P. PAVLOVICH, C. GRANT, et al. 2000. Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice. Diabetes 49: 1106-1115.
9. MANDRUP-POULSEN, T. 1996. The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 39: 1005-1029.
10. OSTERUD, B. & E. BJORKLID. 2003. Role of monocytes in atherogenesis. Physiol. Rev. 83: 1069-1112.
11. SPRANGER, J., A. KROKE, M. MOHLIG, et al. 2003. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 52: 812-817.
12. HOTAMISLIGIL, G.S., P. ARNER, J.F. CARO, et al. 1995. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J. Clin. Invest. 95: 2409-2415.
13. BORST, S.E. 2004. The role of TNF-alpha in insulin resistance. Endocrine 23: 177-182.